The mouse 5-HT2B receptor: homologous subtype or species variant?
Behav Brain Res
; 73(1-2): 253-7, 1996.
Article
en En
| MEDLINE
| ID: mdl-8788513
ABSTRACT
The recently characterized 5-HT2B subfamily of serotonin receptors has now been reported from three different species human, rat and mouse. Their genomic structures include 2 introns present at identical positions. Despite this similarity, their respective protein sequences show some diversities. In addition, the pharmacology of these receptors is distantly related, and their sites of expression vary amongst species. Thus, it appears difficult at present to unambiguously classify these receptors into the same subfamily, raising the possibility of the existence of other 5-HT2B-like receptors, yet to be discovered.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Receptores de Serotonina
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Behav Brain Res
Año:
1996
Tipo del documento:
Article
País de afiliación:
Francia