Use of Polymyxin B Hemoperfusion in a Patient with Septic Shock and Septic Cardiomyopathy Who Was Placed on Extracorporeal Membrane Oxygen Support / 대한구급학회지
The Korean Journal of Critical Care Medicine
; : 123-128, 2016.
Article
en En
| WPRIM
| ID: wpr-770936
Biblioteca responsable:
WPRO
ABSTRACT
Although shock in sepsis is usually managed successfully by conventional medical treatment, a subset of cases do not respond and may require salvage therapies such as veno-arterial extracorporeal membrane oxygenation (VA ECMO) support as well as an attempt to remove endotoxins. However, there are limited reports of attempts to remove endotoxins in patients with septic shock on VA ECMO support. We recently experienced a case of septic shock with severe myocardial injury whose hemodynamic improvement was unsatisfactory despite extracorporeal membrane oxygenation (ECMO) support. Since the cause of sepsis was acute pyelonephritis and blood cultures grew gram-negative bacilli, we additionally applied polymyxin B direct hemoperfusion (PMX-DHP) to the ECMO circuit and were able to successfully taper off vasopressors and wean off ECMO support. To the best of our knowledge, this is the first adult case in which PMX-DHP in addition to ECMO support was successfully utilized in a patient with septic shock. This case indicates that additional PMX-DHP therapy may be beneficial and technically feasible in patients with septic shock with severe myocardial injury refractory to ECMO support.
Palabras clave
Texto completo:
1
Banco de datos:
WPRIM
Asunto principal:
Oxígeno
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Polimixina B
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Pielonefritis
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Choque
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Choque Séptico
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Oxigenación por Membrana Extracorpórea
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Hemoperfusión
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Terapia Recuperativa
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Polimixinas
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Sepsis
Límite:
Adult
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Humans
Idioma:
En
Revista:
The Korean Journal of Critical Care Medicine
Año:
2016
Tipo del documento:
Article