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1.
Ir Med J ; 116(No.1): 10, 2023 01 19.
Artículo en Inglés | MEDLINE | ID: mdl-36916784

RESUMEN

A 21 item questionnaire was disseminated to psychiatry NCHDs working Ireland via the Whatsapp messaging platform, with 63 respondents. The survey initially assessed respondent demographics, with the second part of the survey focused on whether respondents were provided with a work phone. Only respondents who indicated that they were not provided with a work phone were then asked further questions about their mobile phone usage at work.


Asunto(s)
Teléfono Celular , Teléfono Inteligente , Humanos , Encuestas y Cuestionarios , Irlanda
3.
Psychol Med ; 46(15): 3199-3211, 2016 11.
Artículo en Inglés | MEDLINE | ID: mdl-27576609

RESUMEN

BACKGROUND: Many medications administered to patients with schizophrenia possess anticholinergic properties. When aggregated, pharmacological treatments may result in a considerable anticholinergic burden. The extent to which anticholinergic burden has a deleterious effect on cognition and impairs ability to participate in and benefit from psychosocial treatments is unknown. METHOD: Seventy patients were followed for approximately 3 years. The MATRICS consensus cognitive battery (MCCB) was administered at baseline. Anticholinergic burden was measured with the Anticholinergic Cognitive Burden (ACB) scale. Ability to benefit from psychosocial programmes was measured using the DUNDRUM-3 Programme Completion Scale (D-3) at baseline and follow-up. Psychiatric symptoms were measured using the PANSS. Total antipsychotic dose was measured using chlorpromazine equivalents. Functioning was measured using the Social and Occupational Functioning Assessment Scale (SOFAS). RESULTS: Mediation analysis found that the influence of anticholinergic burden on ability to participate and benefit from psychosocial programmes was completely mediated by the MCCB. For every 1-unit increase on the ACB scale, change scores for DUNDRUM-3 decreased by -0.27 points. This relationship appears specific to anticholinergic burden and not total antipsychotic dose. Moreover, mediation appears to be specific to cognition and not psychopathology. Baseline functioning also acted as mediator but only when MCCB was not controlled for. CONCLUSIONS: Anticholinergic burden has a significant impact on patients' ability to participate in and benefit from psychosocial treatment programmes. Physicians need to be mindful of the cumulative effect that medications can have on patient cognition, functional capacity and ability to benefit from psychosocial treatments.


Asunto(s)
Antipsicóticos/uso terapéutico , Antagonistas Colinérgicos/efectos adversos , Cognición , Rehabilitación Psiquiátrica , Esquizofrenia/terapia , Psicología del Esquizofrénico , Adulto , Estudios de Cohortes , Femenino , Humanos , Masculino , Persona de Mediana Edad , Pruebas Neuropsicológicas , Pronóstico , Estudios Prospectivos
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