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1.
A single extraction 96-well method for LC-MS/MS quantification of urinary eicosanoids, steroids and drugs.
Prostaglandins Other Lipid Mediat
; 170: 106789, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-37879396
2.
Development of a Chiral Supercritical Fluid Chromatography-Tandem Mass Spectrometry and Reversed-Phase Liquid Chromatography-Tandem Mass Spectrometry Platform for the Quantitative Metabolic Profiling of Octadecanoid Oxylipins.
Anal Chem
; 94(42): 14618-14626, 2022 10 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-36219822
3.
Synthesis and SAR of potent inhibitors of the Hepatitis C virus NS3/4A protease: exploration of P2 quinazoline substituents.
Bioorg Med Chem Lett
; 20(14): 4004-11, 2010 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20541405
4.
Solid-phase parallel synthesis and SAR of 4-amidofuran-3-one inhibitors of cathepsin S: effect of sulfonamides P3 substituents on potency and selectivity.
Bioorg Med Chem
; 17(3): 1307-24, 2009 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19124252
5.
Preclinical evaluation of 1H-benzylindole derivatives as novel human immunodeficiency virus integrase strand transfer inhibitors.
Antimicrob Agents Chemother
; 52(8): 2861-9, 2008 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-18541726
6.
Automated nano-electrospray mass spectrometry for protein-ligand screening by noncovalent interaction applied to human H-FABP and A-FABP.
J Biomol Screen
; 8(3): 247-56, 2003 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-12857378
7.
Influence of droplet size, capillary-cone distance and selected instrumental parameters for the analysis of noncovalent protein-ligand complexes by nano-electrospray ionization mass spectrometry.
J Mass Spectrom
; 39(9): 1059-67, 2004 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-15386746
8.
Design and synthesis of potent and selective BACE-1 inhibitors.
J Med Chem
; 53(4): 1458-64, 2010 Feb 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-20128595
9.
The design, synthesis, and antiviral activity of 4'-azidocytidine analogues against hepatitis C virus replication: the discovery of 4'-azidoarabinocytidine.
J Med Chem
; 52(1): 219-23, 2009 Jan 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-19055482
10.
The design, synthesis, and antiviral activity of monofluoro and difluoro analogues of 4'-azidocytidine against hepatitis C virus replication: the discovery of 4'-azido-2'-deoxy-2'-fluorocytidine and 4'-azido-2'-dideoxy-2',2'-difluorocytidine.
J Med Chem
; 52(9): 2971-8, 2009 May 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-19341305
11.
Investigation of multiple binding sites on ribonuclease A using nano-electrospray ionization mass spectrometry.
Rapid Commun Mass Spectrom
; 19(8): 1011-6, 2005.
Artículo
en Inglés
| MEDLINE | ID: mdl-15768372
12.
Electrospray ionization mass spectrometry as a tool for determination of drug binding sites to human serum albumin by noncovalent interaction.
Rapid Commun Mass Spectrom
; 19(12): 1637-43, 2005.
Artículo
en Inglés
| MEDLINE | ID: mdl-15915474
13.
On-line microdialysis for enhanced resolution and sensitivity during electrospray mass spectrometry of non-covalent complexes and competitive binding studies.
Rapid Commun Mass Spectrom
; 16(21): 2054-9, 2002.
Artículo
en Inglés
| MEDLINE | ID: mdl-12391580
14.
Mechanism of action of pyridazine analogues on protein tyrosine phosphatase 1B (PTP1B).
Bioorg Med Chem Lett
; 14(4): 891-5, 2004 Feb 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-15012988
15.
Determination of dissociation constants for protein-ligand complexes by electrospray ionization mass spectrometry.
Anal Chem
; 76(15): 4325-31, 2004 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-15283568
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