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J Clin Neurosci ; 72: 485-486, 2020 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-31694779

RESUMEN

Giant cell arteritis (GCA) is the most common vasculitis in patients older than 50 years, and it is occasionally a cause of ischemic stroke. GCA as a paraneoplastic manifestation has been rarely described. We describe a 77-year-old man with a sudden onset of dizziness, vomiting, and gait disturbances. Following imaging studies, a diagnosis of bulbar ischemic stroke with left vertebral artery stenosis was made. Based on a history of polymyalgia rheumatica, on laboratory tests, and brain digital subtraction angiography, a diagnosis of GCA was advanced and the patient underwent high-dose steroidal therapy. After a total body 18-FGD PET imaging, a pulmonary adenocarcinoma was found. Vertebral artery involvement is a rare but important occurrence in GCA as it carries a high mortality rate, and may require a vigorous therapeutic approach. The association of lung cancer and GCA is infrequent, and the relationship between malignancy and GCA remains unclear. Whereas the search for a malignancy in the setting of a GCA is not routinely performed, the use of total body PET when a large vessel vasculitis is suspected may provide useful information on disease and help recognize occult neoplasms.


Asunto(s)
Adenocarcinoma del Pulmón/complicaciones , Isquemia Encefálica/etiología , Arteritis de Células Gigantes/complicaciones , Neoplasias Pulmonares/complicaciones , Accidente Cerebrovascular/etiología , Anciano , Humanos , Masculino , Persona de Mediana Edad , Polimialgia Reumática , Tomografía de Emisión de Positrones , Arteria Vertebral/patología
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