[The impact of the first pandemic waves of COVID-19 in older people with dementia]. / El impacto de las primeras olas pandémicas de la COVID-19 en las personas mayores con demencia.

Patients with dementia are in themselves more vulnerable, and have been especially affected by the effect of the COVID-19 pandemic, both directly due to the disease itself, and indirectly due to the deprivation of cognitive stimulation due to isolation social due to confinement. SARS-CoV-2 virus infection has given rise to a wide variety of symptoms, including neurological symptoms and especially delirium in the elderly with dementia. The virus has affected the central nervous system, both directly due to the neurotropism of the virus, and indirectly due to inflammation and tissue hypoxia of vascular origin. The different causes that have been able to lead, in the different waves prior to the omicron variant, to the significant increase in morbidity and mortality in patients with dementia, especially the elderly, are analyzed.

El impacto de las primeras olas pandémicas de la COVID-19 en las personas mayores con demencia / The impact of the first pandemic waves of COVID-19 in older people with dementia

Los pacientes con demencia son de por sí más vulnerables, y se han visto especialmente afectados por el efecto de la pandemia por COVID-19, tanto de manera directa por la propia enfermedad como de manera indirecta por la privación de estimulación cognitiva debido al aislamiento social por el confinamiento.La infección por el virus SARS-CoV-2 ha dado lugar a una gran variedad de síntomas, entre ellos, síntomas neurológicos, siendo uno de los principales el delirium, especialmente en los ancianos con demencia. La afectación del virus sobre el sistema nervioso central ha sido tanto directa, por el neurotropismo del virus, como indirecta, por la inflamación y la hipoxia tisular de origen vascular.Se analizan las diferentes causas que han podido conducir, en las diferentes olas previas a la variante ómicron, al importante aumento de la morbimortalidad en los pacientes con demencia, especialmente en los más mayores.(AU)

Patients with dementia are in themselves more vulnerable, and have been especially affected by the effect of the COVID-19 pandemic, both directly due to the disease itself, and indirectly due to the deprivation of cognitive stimulation due to isolation social due to confinement.SARS-CoV-2 virus infection has given rise to a wide variety of symptoms, including neurological symptoms and especially delirium in the elderly with dementia. The virus has affected the central nervous system, both directly due to the neurotropism of the virus, and indirectly due to inflammation and tissue hypoxia of vascular origin.The different causes that have been able to lead, in the different waves prior to the omicron variant, to the significant increase in morbidity and mortality in patients with dementia, especially the elderly, are analyzed.(AU)