RESUMEN
BACKGROUND: COVID-19 pandemic has strained human and material resources around the world. Practices in surgical oncology had to change in response to these resource limitations, triaging based on acuity, expected oncologic outcomes, availability of supportive resources, and safety of health care personnel. METHODS: The MD Anderson Head and Neck Surgery Treatment Guidelines Consortium devised the following to provide guidance on triaging head and neck cancer (HNC) surgeries based on multidisciplinary consensus. HNC subsites considered included aerodigestive tract mucosa, sinonasal, salivary, endocrine, cutaneous, and ocular. RECOMMENDATIONS: Each subsite is presented separately with disease-specific recommendations. Options for alternative treatment modalities are provided if surgical treatment needs to be deferred. CONCLUSION: These guidelines are intended to help clinicians caring for patients with HNC appropriately allocate resources during a health care crisis, such as the COVID-19 pandemic. We continue to advocate for individual consideration of cases in a multidisciplinary fashion based on individual patient circumstances and resource availability.
Asunto(s)
Infecciones por Coronavirus/epidemiología , Neoplasias de Cabeza y Cuello/cirugía , Evaluación de Resultado en la Atención de Salud , Pandemias/estadística & datos numéricos , Neumonía Viral/epidemiología , Guías de Práctica Clínica como Asunto/normas , Oncología Quirúrgica/normas , Betacoronavirus , COVID-19 , Instituciones Oncológicas , Control de Enfermedades Transmisibles/normas , Consenso , Infecciones por Coronavirus/prevención & control , Femenino , Neoplasias de Cabeza y Cuello/diagnóstico , Humanos , Masculino , Salud Laboral , Pandemias/prevención & control , Seguridad del Paciente , Selección de Paciente , Neumonía Viral/prevención & control , SARS-CoV-2 , Triaje/normas , Estados UnidosRESUMEN
OBJECTIVE: To evaluate the long-term outcomes and prognostic value of our sonographically based surgical approach to the lateral neck for recurrences in papillary thyroid cancer (PTC). DESIGN: Retrospective medical chart review. SETTING: Tertiary cancer institution. PATIENTS: The study population comprised 331 consecutive patients primarily treated for papillary thyroid carcinoma (PTC) at a tertiary cancer institution between 1996 and 2003. The lateral neck compartments were surgically addressed only in the presence of abnormalities on ultrasonography (US). MAIN OUTCOME MEASURES: Recurrence-free interval and overall, disease-specific, and recurrence-free survival. RESULTS: There were 112 male and 219 female patients, with a median age of 44.7 years (range, 11-87 years). The median follow-up time for the series was 77.9 months (range, 12.7-148.7 months). Preoperative US abnormalities were found in the right neck in 13.3%, in the left neck in 12.3%, and bilaterally in 11.2%; all of these patients underwent a lateral neck dissection at the time of the thyroidectomy. There were 11 recurrences in the series (0.3%), with a median time to presentation of 22.8 months (range, 6.0-55.3 months). Predictors of lateral neck disease-free interval were T stage and distant disease at presentation (P = .01 and P < .001, respectively) and the sonographic status of the ipsilateral and central neck (P = .001 and P < .001). The number of abnormal neck compartments in US correlated with the risk of regional failure (P = .01). The presence of US abnormalities in the lateral neck decreased the 10-year disease-specific survival from 98.3% to 66.9% (P < .001). CONCLUSIONS: Preoperative US is an excellent outcome predictor for lateral neck disease-free interval and for disease-specific survival in PTC. Sonographically based surgical approach provides excellent long-term regional control and validates current treatment guidelines.