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1.
Am J Phys Anthropol ; 157(1): 71-80, 2015 May.
Artículo en Inglés | MEDLINE | ID: mdl-25546319

RESUMEN

Xinjiang is at the crossroads between East and West Eurasia, and it harbors a relatively complex genetic history. In order to better understand the population movements and interactions in this region, mitochondrial and Y chromosome analyses on 40 ancient human remains from the Tianshanbeilu site in eastern Xinjiang were performed. Twenty-nine samples were successfully assigned to specific mtDNA haplogroups, including the west Eurasian maternal lineages of U and W and the east Eurasian maternal lineages of A, C, D, F, G, Z, M7, and M10. In the male samples, two Y chromosome haplogroups, C* and N1 (xN1a, N1c), were successfully assigned. Our mitochondrial and Y-chromosomal DNA analyses combined with the archaeological studies revealed that the Di-qiang populations from the Hexi Corridor had migrated to eastern Xinjiang and admixed with the Eurasian steppe populations in the early Bronze Age.


Asunto(s)
Pueblo Asiatico/genética , Cromosomas Humanos Y/genética , ADN Mitocondrial/genética , Migración Humana , Antropología Física , China , Femenino , Humanos , Masculino , Repeticiones de Microsatélite/genética , Polimorfismo de Nucleótido Simple/genética
2.
Am J Phys Anthropol ; 144(2): 258-68, 2011 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-20872743

RESUMEN

Han Chinese is the largest ethnic group in the world. During its development, it gradually integrated with many neighboring populations. To uncover the origin of the Han Chinese, ancient DNA analysis was performed on the remains of 46 humans (1700 to 1900 years ago) excavated from the Taojiazhai site in Qinghai province, northwest of China, where the Di-Qiang populations had previously lived. In this study, eight mtDNA haplogroups (A, B, D, F, M*, M10, N9a, and Z) and one Y-chromosome haplogroup (O3) were identified. All analyses show that the Taojiazhai population presents close genetic affinity to Tibeto-Burman populations (descendants of Di-Qiang populations) and Han Chinese, suggesting that the Di-Qiang populations may have contributed to the Han Chinese genetic pool.


Asunto(s)
Pueblo Asiatico/genética , ADN Mitocondrial/genética , Fósiles , Análisis de Varianza , Secuencia de Bases , Huesos/química , China , Cromosomas Humanos Y , Análisis por Conglomerados , ADN Mitocondrial/aislamiento & purificación , Femenino , Pool de Genes , Humanos , Masculino , Datos de Secuencia Molecular , Polimorfismo de Nucleótido Simple , Análisis de Componente Principal , Diente/química
3.
Am J Phys Anthropol ; 133(4): 1128-36, 2007 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-17506489

RESUMEN

Ancient DNA analysis was conducted on the dental remains of specimens from the Lajia site, dating back 3,800-4,000 years. The Lajia site is located in Minhe county, Qinghai province, in northwestern China. Archaeological studies link Lajia to the late period of the Qijia culture, one of the most important Neolithic civilizations of the upper Yellow River region, the cradle of Chinese civilization. Excavations at the site revealed that the inhabitants died in their houses as the result of a sudden flood. The Lajia site provides a rare chance to study the putative families, all of whom died at the same instant. Possible maternal familial relationships were investigated through mitochondrial DNA (mtDNA) sequence analysis. Twelve sequences from individuals found in one house were assigned to only five haplotypes, consistent with a possible close kinship. Results from analyses of RFLP typing and HVI motifs suggest that the Lajia people belonged to the haplogroups B, C, D, M*, and M10. This study, combined with archaeological and anthropological investigations, provides a better understanding of the genetic history of the Chinese people.


Asunto(s)
Pueblo Asiatico/historia , ADN Mitocondrial/química , Pueblo Asiatico/genética , China , ADN Mitocondrial/clasificación , Femenino , Haplotipos , Historia Antigua , Humanos , Masculino , Filogenia , Polimorfismo de Longitud del Fragmento de Restricción , Análisis de Secuencia de ADN
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