The past tense inflection project (PTIP): speeded past tense inflections, imageability ratings, and past tense consistency measures for 2,200 verbs.

The processes involved in past tense verb generation have been central to models of inflectional morphology. However, the empirical support for such models has often been based on studies of accuracy in past tense verb formation on a relatively small set of items. We present the first large-scale study of past tense inflection (the Past Tense Inflection Project, or PTIP) that affords response time, accuracy, and error analyses in the generation of the past tense form from the present tense form for over 2,000 verbs. In addition to standard lexical variables (such as word frequency, length, and orthographic and phonological neighborhood), we have also developed new measures of past tense neighborhood consistency and verb imageability for these stimuli, and via regression analyses we demonstrate the utility of these new measures in predicting past tense verb generation. The PTIP can be used to further evaluate existing models, to provide well controlled stimuli for new studies, and to uncover novel theoretical principles in past tense morphology.

A feasibility study of several 3D printing methods for applications in epilepsy surgery.

OBJECTIVE: To describe the process of three-dimensional printing in epilepsy surgery using three different methods: low-force stereolithography (SLA), filament deposition modeling (FDM), and Polyjet Stratasys, while comparing them in terms of printing efficiency, cost, and clinical utility. MRI and CT images of patient anatomy have been limited to review in the two-dimensional plane, which provides only partial representation of intricate intracranial structures. There has been growing interest in 3D printing of physical models of this complex anatomy to be used as an educational tool and for surgical visualization. One specific application is in epilepsy surgery where there are challenges in visualizing complex intracranial anatomy in relation to implanted surgical tools. METHODS: MRI and CT data from patients with refractory epilepsy from a single center that underwent surgery are converted into 3D volumes, or stereolithography files. These were then printed using three popular 3D printing methods: SLA, FDM, and Polyjet. Faculty were surveyed on the impact of 3D modeling on the surgical planning process. RESULTS: All three methods generated physical models with an increasing degree of resolution, transparency, and clinical utility directly related to cost of production and accurate representation of anatomy. Polyjet models were the most transparent and clearly represented intricate implanted electrodes but had the highest associated cost. FDM produced relatively inexpensive models that, however, were nearly completely opaque, limiting clinical utility. SLA produced economical and highly transparent models but was limited by single material capacity. SIGNIFICANCE: Three-dimensional printing of patient-specific anatomy is feasible with a variety of printing methods. The clinical utility of lower-cost methods is limited by model transparency and lack of multi-material overlay respectively. Polyjet successfully generated transparent models with high resolution of internal structures but is cost-prohibitive. Further research needs to be done to explore cost-saving methods of modeling.