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1.
Pharmazie ; 68(3): 201-6, 2013 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-23556339

RESUMEN

We investigated the possible association of Interleukin-10 (IL-10) single nucleotide polymorphisms (SNPs) and susceptibility to acute myeloid leukemia (AML) in 115 AML patients and 137 gender- and age-matched controls. Genetic analysis of IL-10 SNPs at -819 and -592 was carried out by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Results revealed that the -819AA genotype frequencies and the -819A allele frequencies of AML group were higher than the controls (59.1% vs 40.9%; 75.6% vs 63.9%, respectively); there were remarkable differences in -819T/C and -592A/C gene distribution (P<0.05) and the TA haploid frequencies were higher in AML group (75.6% vs 63.9%, P<0.05). The IL-10 mRNA expression of AML patients and controls with different genotype was detected by Real-time quantitative Polymerase Chain Reaction (RT-PCR). IL-10 mRNA expression in incipient AML patients increased obviously compared with the non-tumor group and remission group (P<0.05). Further analysis suggested that the IL-10 mRNA expression of TA/TA genotype was the lowest and CC/CC genotype was the highest; the haploid TA and genotype TA/TA may be associated with AML. The research suggested the IL-10 SNPs at -819 and -592 sites were associated with AML and may affect the IL-10 mRNA expression in AML patients in Han people of Hunan province.


Asunto(s)
Interleucina-10/biosíntesis , Interleucina-10/genética , Leucemia Mieloide Aguda/genética , Leucemia Mieloide Aguda/metabolismo , Regiones Promotoras Genéticas/genética , Alelos , Médula Ósea/metabolismo , Cartilla de ADN , Predisposición Genética a la Enfermedad/genética , Genotipo , Haploidia , Desequilibrio de Ligamiento , Reacción en Cadena de la Polimerasa , Polimorfismo de Nucleótido Simple/genética , ARN Mensajero/biosíntesis , ARN Mensajero/genética
2.
Environ Sci Pollut Res Int ; 30(15): 42889-42903, 2023 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-35025050

RESUMEN

Environmental issues have gained the attention of regulators and researchers worldwide. This present study empirically examines the validation of the environmental Kuznets curve (EKC) in the selected ASEAN economies for the period 1995-2018 in the presence of eco-innovations and tourism. This study assesses the short-run and long-run relationship between carbon dioxide emission, tourism, eco-innovations, and economic growth in ASEAN countries. To fulfil the objectives of the study, Westerlund and Edgerton (Oxf Bull Econ Stat 70:665-704, 2008) and Banerjee and Carrion-i-Silvestre (J Time Ser Anal 38:610-636, 2017) co-integration analysis have been applied to estimate the co-integration among variables because cross-sectional dependence (CSD) and slope heterogeneity was present. The short-run and the long-run empirical estimation have been done through cross-sectional auto distributive lag model. The findings provide evidence that an inverted U-shape nexus exists between carbon (CO2) emissions and economic growth in the ASEAN countries, a validation of EKC. Eco-innovations and tourism are found to be the factors that mitigate CO2 emissions. AMG and CCEMG results also confirm the robustness of short-run and long-run results. The findings of the study suggest that governments in ASEAN countries should promote tourism and eco-innovations (i.e., research and development) to mitigate CO2 emission, which poses serious threats to environmental sustainability. Also, tourism and eco-innovations are the drivers of economic growth, and growth reconciles with environmental sustainability in the selected ASEAN countries. This study provides guidelines to the policymakers while formulating the regulations related to environmental degradation.


Asunto(s)
Dióxido de Carbono , Turismo , Masculino , Animales , Bovinos , Estudios Transversales , Desarrollo Económico , Gobierno
3.
J Orthop Surg Res ; 17(1): 255, 2022 May 07.
Artículo en Inglés | MEDLINE | ID: mdl-35526015

RESUMEN

BACKGROUND: Since Mohamed et al. analyzed 2326 orthopedic cases in 2002 and believed that the POSSUM formula can be directly used to predict postoperative morbidity and mortality in orthopedic patients, applications of POSSUM and P-POSSUM scores in the hip fracture surgery have been mostly reported in the field of orthopedics, but there are still some inconsistencies in the related reports. METHODS: The electronic library was searched for all literature that met the purpose from its inception to 2021. Relative risk (RR) was selected to evaluate whether the model could be used to assess the risk of surgery in patients with elderly hip fractures. Finally, sensitivity analyses and subgroup analyses were performed. RESULTS: Thirteen studies were finally included, including 9 retrospective and 4 prospective studies.The morbidity analysis includes 11 studies, and the result was RR = 1.07 (95% CI 0.93-1.24), The mortality analysis includes 11 studies on POSSUM and 5 studies on P-POSSUM. The results of mortality by POSSUM and by P-POSSUM were RR = 1.93 (95% CI 1.21-3.08) and RR = 1.15 (95% CI 0.89-1.50), respectively. POSSUM had more accuracy to predict mortality for sample < 200 subgroup(RR = 2.45; 95% CI 0.71-8.42) than sample > 200 subgroup(RR = 1.59; 95% CI 1.06-2.40), and in the subgroup of hip fractures that did not distinguish between specific fracture types(RR = 1.69, 95% CI 0.87-3.32) than intertrochanteric neck fracture subgroup(RR = 5.04, 95% CI 1.07-23.75) and femoral femoral fracture subgroup(RR = 1.43,95% CI 1.10-1.84). CONCLUSION: POSSUM can be used to predict morbidity in elderly hip fractures. The P-POSSUM was more accurate in predicting mortality in elderly hip fracture patients compared to the POSSUM, whose predictive value for mortality was influenced by the sample size and type of fracture studied. In addition, we believe that appropriate improvements to the POSSUM system are needed to address the characteristics of orthopedic surgery.


Asunto(s)
Fracturas de Cadera , Anciano , Fracturas de Cadera/cirugía , Humanos , Morbilidad , Estudios Prospectivos , Estudios Retrospectivos , Medición de Riesgo
4.
J Hazard Mater ; 389: 121914, 2020 05 05.
Artículo en Inglés | MEDLINE | ID: mdl-31879114

RESUMEN

Dry flue gas desulfurization is an increasingly attractive technique in SO2 emission control. However, the low efficiency in dry desulphurization is the bottleneck of this technology. To find a high-performance desulfurizer is an urgent task. This research utilized a steam jet mill digestion to prepare a desulfurizer at steam temperature of 220 ℃ and pressure of 0.45 MPa, and compared this product with the conventional digestion desulfurizer. Our results show that the digestion in steam jet mill can transform all the calcium oxide into calcium hydroxide. The calcium hydroxide had good fluidity and with honeycomb morphological characteristics. The experiments of dry flue gas desulfurization demonstrated that under the relative humidity of 15, 30 and 45%, the total dead times were 340, 640 and 720 min, the working time for keeping a 100% desulfurization efficiency were 120, 420 and 580 min, and the total sulfur fixation were 124.05, 274.58 and 332.09 mg. Compared with the desulfurizer by conventional dry digestion, the desulfurizer prepared in this research had a significantly superior performance. This experiment provides a new method for high-performance desulfurizer via quicklime digestion, which is an important step in pushing forward the application of dry flue gas desulfurization.

5.
Microvasc Res ; 78(1): 128-31, 2009 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-19289136

RESUMEN

Several lines of evidence supported the involvement of ECE-1 in the development of atherosclerosis disease. We investigated the C-338A polymorphism of the ECE-1b gene in carotid atherosclerosis. A cohort of 518 Chinese carotid atherosclerosis patients and 518 controls matched by age and sex were examined for the ECE-1b C-338A polymorphism. The ECE-1b-338 A allele was significantly frequent in carotid atherosclerosis patients than in controls (chi(2)=9.167; P=0.002). A alleles had a 26% increased risk of carotid atherosclerosis compared with C alleles (OR=1.26; 95% CI=1.05-1.52). In stratified analyses, the A allele carrying genotypes was significantly associated with an increased risk of carotid atherosclerosis in females (adjusted OR=1.57; 95% CI=1.14-2.23) and a subject with age >or=64 years (adjusted OR=1.72; 95% CI=1.23-1.41). Our results suggested that ECE-1b-338 A allele carrying genotypes might be associated with increased risk of carotid atherosclerosis in the Chinese population.


Asunto(s)
Pueblo Asiatico/genética , Ácido Aspártico Endopeptidasas/genética , Enfermedades de las Arterias Carótidas/genética , Predisposición Genética a la Enfermedad , Metaloendopeptidasas/genética , Polimorfismo Genético , Factores de Edad , Anciano , Alelos , Estudios de Casos y Controles , Distribución de Chi-Cuadrado , China , Estudios de Cohortes , Intervalos de Confianza , Enzimas Convertidoras de Endotelina , Femenino , Frecuencia de los Genes , Humanos , Masculino , Persona de Mediana Edad , Oportunidad Relativa , Factores de Riesgo , Factores Sexuales
6.
Chinese Journal of Nursing ; (12): 117-123, 2024.
Artículo en Zh | WPRIM | ID: wpr-1027821

RESUMEN

Acute coronary syndrome(ACS)is a common type of acute and critical disease in Coronary Heart Disease(CHD).It is characterized by multiple and severe symptoms and rapid progression of the disease,which seriously threatens the life safety of patients.In this paper,the relevant studies on symptom cluster of patients with ACS were systematically searched at home and abroad,and the composition of symptom cluster,symptom assessment tools,symptom cluster establishment methods,influencing factors and intervention methods were reviewed,in order to provide references for nurses to manage ACS symptom cluster.

7.
Modern Hospital ; (6): 250-253,257, 2024.
Artículo en Zh | WPRIM | ID: wpr-1022250

RESUMEN

Objective Toexplore a path to improving surgical operation statistical indexes during the expansion of multi-campus hospitals.Methods In this study we selected the data from the medical records of two surgical departments(A1 and A2)from two campuses of a hospital in the first half of 2023,following by analyzing patients'general information,fourth-level surgical procedures,non-fourth-level surgical procedures,and disease types to identify the reasons for the discrepancies in the in-dicators between the two departments and make suggestions for improvement.Results The A2 department in the branch hospital performed significantly more laparoscopic procedures than the A1 department in the home hospital(P<0.01).Moreover,the prevalence of the patients diagnosed with chemotherapy and malignant melanoma in the A2 department was significantly higher than in the A1 department(P<0.01),impacting the surgical rate indicator for the branch area.Conclusion A systematic anal-ysis of medical record data can effectively pinpoint the reasons for indicator discrepancies among different campuses within the same surgical departments of a hospital.Implementing outpatient-specific disease management and encouraging admission of com-plex and critically ill patients can effectively enhance the surgical rate as well as the fourth-level surgical rate in a department.It is suggested for the home hospital and its branches to set a respective indicator management target as long as the gap in the factors influencing the surgical rate indicators is unbridgeable between the campuses.

8.
Artículo en Zh | WPRIM | ID: wpr-1020460

RESUMEN

Patients with chronic obstructive pulmonary disease have the disease phenomenon of fear of exercise because of dyspnea, which can accelerate the body degradation rate, weaken muscle strength, reverse increase dyspnea, and delay the recovery of the disease. As a result, this article examines the theoretical underpinnings and specific measures of dyspnea belief intervention programs for chronic obstructive pulmonary disease patients at home and abroad, summarizes the limitations of previous studies, and makes pertinent recommendations in an effort to serve as a guide for early patient prevention and the development of scientific and feasible intervention programs.

9.
Tianjin Medical Journal ; (12): 278-284, 2024.
Artículo en Zh | WPRIM | ID: wpr-1021010

RESUMEN

Objective To explore the mechanism of Wumei pill on ulcerative colitis(UC)in mice based on the anti oxidative stress pathway of nuclear factor erythroid 2-related factor 2(Nrf2)/antioxidant response element(ARE).Methods Seventy SPF male C57BL/6 mice were randomly divided into the control group,the UC group,the mesalazine group(MES group,0.82 g/kg MES),the low dose Wumei pill group(WMW-L group,5 g/kg crude drug),the middle dose Wumei pill group(WMW-M group,10 g/kg crude drug),the high dose Wumei pill group(WMW-H group,20 g/kg crude drug)and the high dose Wumei pills+Nrf2 inhibitor ML-385 group(WMW-H+ML-385 group,Wumei pills crude drug 20 g/kg+20 mg/kg ML-385),with 10 rats in each group.The disease activity index(DAI)score and colonic mucosa injury score were performed in mice after the last administration.Pathological changes of colonic mucosa in mice were observed by HE staining.The levels of interleukin(IL)-1β,tumor necrosis factor-α(TNF-α)and IL-6 in serum and colon tissue of mice were measured by enzyme-linked immunosorbent assay(ELISA).The content of malondialdehyde(MDA)in serum and colon tissue of mice was determined by thiobarbituric acid colorimetry(TBA).The activity of superoxide dismutase(SOD)in serum and colon tissue of mice was measured by xanthine oxidase method.The activity of glutathione peroxidase(GSH-px)in serum and colon tissue of mice was determined by direct method with dithiodinitrobenzoic acid(DTNB).The positive expression of Nrf2 in colon tissue of mice was observed by immunohistochemistry.The expression of heme oxygenase-1(HO-1)and NAD(P)H:quinone oxidoreductase-1(NQO1)proteins in colon tissue of mice were detected by Western blot assay.Results Compared with the control group,the DAI score,colonic mucosa injury score,colonic histopathology score,levels of IL-1β,TNF-α,IL-6 and MDA in serum and colonic tissue,and expression levels of Nrf2,HO-1 and NQO1 protein in colonic tissue of mice were increased in the UC group,levels of SOD and GSH-px in serum and colon tissue decreased(P<0.05),the colon mucosa of mice was seriously damaged.Compared with the UC group,changes of corresponding indexes were contrary to the above in the MES group,the WMW-M group and the WMW-H group.However,the expression levels of Nrf2,HO-1 and NQO1 proteins in colon tissue were increased(P<0.05),and the damage of colon mucosa in mice was alleviated.Changes of the above indexes were dose-dependent in the WMW-L group,the WMW-M group and the WMW-H group.There were no significant differences in the above indexes between the WMW-H group and the MES group.ML-385 attenuated the improvement effect of high dose Wumei pill on colon mucosa injury.Conclusion Wumei pill may alleviate the colon mucosal damage of UC mice by activating Nrf2/ARE antioxidant stress pathway.

10.
Artículo en Zh | WPRIM | ID: wpr-1039892

RESUMEN

ObjectiveTo understand the current status of human immunodeficiency virus (HIV), Treponema pallidum (TP), hepatitis C virus (HCV) and hepatitis B virus (HBV) infections among patients undergoing screening tests in a specialized cancer hospital in South China, and to analyze the completion of further testing for confirmation, so as to provide a reference for management of common infectious diseases and prevention of nosocomial infections. MethodsWe analyzed the positive rates of HIV antigen/antibody combination assay (HIV-comb), TP antibody (anti-TP), HCV antibody (anti-HCV) and hepatitis B surface antigen (HBsAg) among the outpatients and inpatients who underwent the screening tests in 2022. Then we examined the percentage of those patients with seropositivity for further confirmation. ResultsIn patients who underwent the screening tests, the positive rate, percentage of patients for further confirmation test and overall prevalence for HIV-comb were were 0.07%, 100% and 0.06%, respectively; for Anti-PT 1.99%, 100% and 0.51%, respectively. Positive rate of anti-HCV was 0.90% and 26.61% of patients completed further HCV RNA quantitative assay, in 26.44% of whom, HCV RNA levels were above the detection limit. Positive rate of HBsAg was 21.06% and 54.40% of patients completed further HBV DNA quantitative assay, in 51.60% of whom, HBV DNA levels were above the detection limit. As for the nucleic acid testing among the suspected hepatitis patients, we found smaller coverage in outpatients than in inpatients and larger coverage in liver cancer patients than in other patients. ConclusionsCompared with general population, patients in this specialized cancer hospital had similar infection levels of HIV and syphilis, and 100% of them completed further confirmation testing. Hepatitis C and hepatitis B infections were at a relatively high level, but which could not accurately reflect the level of virus replication due to insufficient coverage of nucleic acid testing. Specialized cancer hospitals should prompt medical staff to attach more importance to screening and further confirmation of common infectious diseases among tumor patients. While offering anti-cancer treatment, hospitals should also actively refer the confirmed cases with infectious diseases to designated or general hospitals for a better outcome and quality of medical services.

11.
Artículo en Zh | WPRIM | ID: wpr-1017040

RESUMEN

Objective To investigate the radioactivity levels of gross α and gross β in foods around Zhangzhou nuclear power plant, China before operation. Methods Forty-nine samples from 33 kinds of foods in 5 categories of daily food around Zhangzhou nuclear power plant were collected, pretreated, dried, and ashed. The radioactivity levels of gross α and gross β were measured by the low-background α and β measuring instrument. The atomic absorption technique was employed to measure the level of potassium (K), and the radioactivity level of gross β (subtracting 40K) was calculated with K concentrations in different foods consulted from the nutritional dietary system. Results The radioactivity levels of gross α in vegetables and fruits, grain, poultry and livestock, aquatic products, and tea around Zhangzhou nuclear power plant were < minimum detectable level (MDL)-7.97, < MDL-6.82, < MDL, < MDL-20.76, and 11.90-23.08 Bq/kg, respectively; the radioactivity levels of gross β were 34.56-122.81, 13.05-188.96, 56.00-108.34, 17.86-169.01, and 123.74-171.63 Bq/kg, respectively; the radioactivity levels of gross β (subtracting 40K) were not detected (ND)-14.27, ND-27.86, ND-48.72, ND-45.85, and 6.69-13.79 Bq/kg, respectively. Conclusion The radioactivity of gross α and gross β in foods around Zhangzhou nuclear power plant before operation is basically at the same level as that in other areas of China.

12.
Artículo en Inglés | WPRIM | ID: wpr-1043918

RESUMEN

Background/Aims@#Previous studies have shown that diet and physical activity can influence constipation. However, the combined effect of diet and physical activity on constipation remains unclear. @*Methods@#Constipation was defined based on stool consistency and frequency, while overall diet quality was assessed using Healthy Eating Index (HEI)-2015 scores. Participants were categorized into low (metabolic equivalent [MET]-min/wk < 500) and high physical activitygroups (MET-min/wk ≥ 500). The association between diet and constipation across physical activity groups was analyzed using surveylogistic regression and restricted cubic splines. @*Results@#Higher HEI-2015 scores were associated with reduced constipation risk in the high physical activity group when constipation was defined by stool consistency (odds ratio [OR], 0.98; 95% confidence interval [CI], 0.97-0.99). However, in the low physical activity group, increased HEI-2015 scores did not significantly affect constipation risk (OR, 1.01; 95% CI, 0.97-1.05). Similar results were found when constipation was defined based on stool frequency. In the high physical activity group, increased HEI-2015 scores were significantly associated with a reduced constipation risk (OR, 0.96; 95% CI, 0.94-0.98). Conversely, in the low physical activity group, increased HEI-2015 scores did not affect the risk of constipation (OR, 0.96; 95% CI, 0.90-1.03). @*Conclusions@#Our findings suggest that a higher HEI-2015 score is negatively associated with constipation among individuals with high physical activity levels but not among those with low physical activity levels. This association was consistent when different definitions of constipation were used. These results highlight the importance of combining healthy diet with regular physical activity to alleviate constipation.

13.
Artículo en Zh | WPRIM | ID: wpr-990445

RESUMEN

Objective:To investigate the status of participation in treatment and nursing decision-making in patients with chronic obstructive pulmonary disease (COPD), and analyze its influencing factors.Methods:A cross-sectional survey was conducted on 230 COPD patients hospitalized in the Affiliated Hospital of Hangzhou Normal University from October 2021 to May 2022 by using the general situation questionnaire, questionnaire of patients′ decision-making regarding treatment and care, Patient Doctor Relationship Questionnaire, 13-Item Version, Nursing-Patient Relationship Trust Scale and Chronic Obstructive Pulmonary Disease knowledge Questionnaire, Logistic regression was used to analyze the influencing factors of patients′ participation in treatment and nursing decision-making.Results:The participation attitude score of COPD patients′ treatment decision-making was (1.93 ± 0.55) points, the participation degree score of COPD patients′ treatment decision-making was (2.29 ± 0.46) points, the participation attitude score of COPD patients′nursing decision-making was (1.84 ± 0.42) points, and the participation degree score of COPD patients′ nursing decision-making was (2.03 ± 0.35) points. Gender, education level, occupation or occupation before retirement, the number of hospitalizations due to acute exacerbation of COPD in the past year, modified medical research council, doctor-patient relationship, and nurse-patient relationship were the influencing factors for patients to participate in treatment and nursing decision-making ( OR values were 0.070 to 18.368, all P<0.05). Conclusions:The participation attitude of COPD patients in treatment and nursing decision-making is negative and the degree of participation is low. Medical staff should correctly assess the reasons for the low participation of patients, and take targeted individualized measures to support patients to actively participate in treatment and nursing decision-making.

14.
Artículo en Inglés | WPRIM | ID: wpr-928650

RESUMEN

Neurocognitive impairment is a group of clinical syndromes characterized by impaired cognitive function and decreased motor ability. Non-pharmacological interventions such as physical exercise have advantages in the treatment of patients with neurocognitive impairment. Multicomponent exercise is a combination of various physical exercises, including strength training, endurance training, balance training and flexibility training, that can improve gait, balance and cardiopulmonary function by increasing muscle mass, strength and endurance in people with neurocognitive impairment, while also reducing the risk of falls in elders. This article reviews the benefits of multicomponent exercise for patients with neurocognitive impairment and its evaluation methods; also describes 4 intervention programs and their clinical application, to provide evidence for clinical practice and promote the application of multicomponent exercise in patients with neurocognitive impairment.


Asunto(s)
Anciano , Humanos , Accidentes por Caídas , Cognición , Ejercicio Físico/fisiología , Marcha , Entrenamiento de Fuerza
15.
Artículo en Zh | WPRIM | ID: wpr-957246

RESUMEN

Objective:To summarize the best evidence of physical activity (PA) in patients with chronic obstructive pulmonary disease (COPD).Methods:According to the 6S evidence model, BMJ Best Practice, UpToDate, Joanna Briggs Institute (JBI) database, National Guideline Clearinghouse (NGC), National Institute for Health and Clinical Excellence (NICE) network, Scottish Intercollegiate Guidelines Network (SIGN), Guidelines International Network (GIN), New Zealand Guideline Group (NZGG) network, Registered Nurses′ Association of Ontario (RNAO) network, Medlive, PubMed, Web of Science, Cochrane Library, CNKI, Wanfang Knowledge Data Service Platform, VIP database and Chinese Biomedical Database and European Respiratory Society/American Thoracic Society were searched systematically to obtain guidelines, expert consensus, best practice information book, clinical decision-making, recommended practice, and systematic review on PA management in patients with COPD. The data retrieval time was from the establishment of the databases to April 30, 2022. Two researchers with evidence-based medicine background evaluated the quality and extracted evidence of the included literature.Results:A total of 19 articles were selected including 4 guidelines, 2 clinical decision, 9 systematic reviews, 3 expert consensus and 1 randomized controlled trial. Finally, 33 pieces of best evidence were formed from 10 themes, namely pre-exercise assessment, exercise prescription, exercise style, time, intensity, PA location, safety and effectiveness of PA, intervention strategies, effect evaluation and quality control.Conclusions:This study summarizes the best evidence of PA in patients with COPD. Health professionals should choose and apply the best evidence with consideration of the clinical situation and patient preference.

16.
Artículo en Zh | WPRIM | ID: wpr-930579

RESUMEN

Occupational contact dermatitis is the most common occupational skin disease. It has a high incidence among healthcare workers, especially nurses. It has an impact on work and life. This paper reviews the research progress, risk factors, intervention measures, evaluation indicators of nurses′ hand occupational contact dermatitis, and provides references for the future researches.

17.
Artículo en Zh | WPRIM | ID: wpr-932601

RESUMEN

Objective:To investigate the differences in applicability of both the portable high-purity germanium (HPGe) γ spectrometer and the portable lanthanum bromide (LaBr) γ spectrometer for measuring thyroid 131I activity and internal exposure monitoring for radiation workers. Method:Both DETECTIVE-DX100-KT portable HPGe γ spectrometer and InSpector 1000 portable LaBr γ spectrometer were used to measure the 131I content in thyroid of radiation workers for comparison of the measuring result, minimum detectable activity (MDA) and corresponding annual committed effective doses between two types of spectrometers. Results:The detection rate of 131I in thyroid of radiation workers was 67.7% for HPGe γ spectrometer and 26.2% for LaBr γ spectrometer, respectively. The MDA was 12.26-14.74 Bq (measuring time: 3-5 min) for HPGe γ spectrometer and 56.56-80.37 Bq for LaBr γ spectrometer (measuring time: 2-4 min). The annual committed effective dose corresponding to MDA was 0.07-0.08 mSv (3-5 min) for HPGe and 0.31-0.45 mSv (2-4 min) for LaBr, respectively, in the case of using chronic continuous intake mode and 7 d monitoring period. Conclusions:The minimum detectable activity (MDA) of the two types of portable spectrometers could meet the requirements specified in GBZ 129-2016 Specifications for individual monitoring of occupational internal exposure for thyroid monitoring equipment. The two types of spectrometers could be used for routine monitoring of internal contamination. The difference between the monitoring result of LaBr γ and HPGe γ spectrometers might be due to such factors as large uncertainty in short measuring time and low activity concentrations, incomplete identical of distance between probe and neck, probe angle setting, different response of equipment to the environment, background deduction method.

18.
Artículo en Zh | WPRIM | ID: wpr-908251

RESUMEN

Objective:To translate the English version and cross-cultural adaptation of Readiness for Return-To-Work Scale (RRTW) into Chinese and tested the reliability and validity of the Chinese version of RRTW in young and middle-aged stroke patients.Methods:RRTW was translated into Chinese with standard translation-retroversion. From August to December 2020, 235 stroke patients in the First Affiliated Hospital, College of Medicine, Zhejiang University were recruited by convenient sampling. The scale was tested by the reliability and validity.Results:The Chinese version of RRTW for stroke was composed of two parts: The first part was divided into four dimensions, with a total of 13 entries; For the unworked stroke population, the second part was divided into two dimensions, with a total of nine entries for the reworked stroke population. The content validity index (CVI) for each item was from 0.875 to 1.000. The total CVI for all items was 0.994. The Pearson correlation coefficient between dimension and scale was from 0.523 to 0.876. Four common factors were obtained from the first part and the cumulative contribution rate was 62.563%. Two common factors were obtained from the second part and the cumulative contribution rate was 49.908%. The Cronbach α coefficient in the first part was 0.760 and in the second part was 0.693.Conclusions:The Chinese version of RRTW for stroke patients has good reliability and validity, which can be used to assess the readiness level of stroke patients to return to work in Chinese society.

19.
Artículo en Zh | WPRIM | ID: wpr-910414

RESUMEN

Objective:To explore the assessment methodology for internal dose to workers exposed to 131I radionuclide. Methods:Workers were chosen in a 131I radiopharmaceutial manufacturer and a nuclear medicine department in a hospital using 131I to treat hyperthyroidism and thyroid cancer. A portable high purity germanium (HPGe) gamma spectrometer was used to measure the content of 131I in the thyroid for 4 consecutive times in a period of 7 d. The internal dose was estimated combining with the work rotation mode for workers dealing with 131I. Results:When the monitoring month was used as a typical month to estimate the internal dose, the annual committed effective dose was 0.09-1.93 mSv for the production staff engaged in the repackaging of 131I radiopharmaceuticals in the surveyed enterprise, and 0.06-0.58 mSv for the nuclear medicine staff in the surveyed hospital. After adjusting the monitoring result of the current monitoring period based on the rotation mode, the annual committed effective dose was estimated to be 0.06-1.22 mSv for radiopharmaceutical production workers and 0.03-0.15 mSv for nuclear medicine workers, respectively. Conclusions:In the assessment of internal dose to radiation workers exposed to 131I, using a single time measurement result to estimate the annual dose would lead to a larger error. In the case of continuous monitoring, the result of subsequent monitoring periods should be corrected according to the result of previous monitoring periods. In order to accurately estimate the internal dose of workers exposed to 131I, it is necessary to take full account of the 131I exposure pattern, time and frequency and the internal contamination route. For workers who may be exposed to 131I with potential internal dose greater than 1 mSv/year, a 14 day-routine monitoring period was appropriate.

20.
Artículo en Zh | WPRIM | ID: wpr-974572

RESUMEN

Objective To investigation the radioactivity level of 90Sr in tea leaves within and outside 30 km range of Ningde nuclear power plant. Methods The tea leaves within and outside the 30 km range of Ningde Nuclear Power Plant were collected from 2013 to 2018. According to“Radiochemical analysis of strontium-90 in water and ash of biological samples” (HJ 815—2016), the separation and analysis of 90Sr-90Y were carried outusing the method of di (2-ethylhexyl) phosphate (HDEHP) chromatography. Results During the period of 2013-2018, the radioactivity concentrations of 90Sr in the tea leaves within the range of 30 km around the Ningde nuclear power plant were 0.486~13.29 Bq/kg and that of 90Sr in the tea leaves outside the range of 30 km around the nuclear power station were 1.021~17.19 Bq/kg. Conclusion During the six years of operation in Ningde Nuclear Power Plant, there was no increase in the radioactivity level of 90Sr in the tea leaves around the nuclear power plant.

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