[The surgical treatment of haemophilic arthropathy (author's transl)]. / Indications du traitement chirurgical dans l'arthropathie hémophilique.

The authors have operated on 13 haemophilic joints. The operation included 5 knee synovectomies of the knee, 2 corrective osteotomies, 4 soft tissue procedures on the knee or foot (tendon lengthening, capsulotomy), 1 arthrodesis of knee and 1 excision of heterotopic ossification. The type of operation needed varied with the degree of involvement. Indications for associated haematological treatment are given. The indications were both preventive and curative. The results were gratifying, although two cases of post-operative infection were seen.

Human parvovirus B19: a new emerging pathogen of inflammatory cardiomyopathy.

The human parvovirus B19 (PVB19), an erythrovirus causing diverse clinical manifestations ranging from asymptomatic or mild to more severe outcomes such as hydrops fetalis, is the only known human pathogenic parvovirus so far. Although enteroviruses have long been considered the most common cause of inflammatory cardiomyopathy, PVB19 is emerging as a important candidate. Recent studies have indicated an association of PVB19 with paediatric and adult inflammatory cardiac disease. However, whether or not PVB19 has an impact on inflammatory cardiomyopathy in adult patients is still unclear. The first hints for a possible aetiopathogenetic role of the PVB19-infection and the development of cardiac dysfunction were demonstrated by molecular biology utilizing in situ hybridization (ISH) and polymerase chain reaction (PCR). According to available evidence, PVB19-associated inflammatory cardiomyopathy is characterized by infection of endothelial cells of small intracardiac arterioles and venules, which may be associated with endothelial dysfunction, impairment of myocardial microcirculation, and penetration of inflammatory cells into the myocardium.

[Possibilities of surgical treatment in hemophiliac arthropathy]. / Posibilitatile tratamentului chirurgical în artropatia hemofilica.

The possibilities are discussed of the surgical treatment in haemophiliac arthropathies. The cases that have been treated totalled 11 patients with type A haemophilia and one patient with type B haemophilia. The treatment was aimed either at an arrest of deterioration in the involved joint (in the early, I and II stages), or at correcting the vicious positions that had developed in the late stages (III and IV).