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1.
Proc Natl Acad Sci U S A ; 118(6)2021 02 09.
Artículo en Inglés | MEDLINE | ID: mdl-33526686

RESUMEN

To explain the political clout of different social groups, traditional accounts typically focus on the group's size, resources, or commonality and intensity of its members' interests. We contend that a group's penumbra-the set of individuals who are personally familiar with people in that group-is another important explanatory factor that merits systematic analysis. To this end, we designed a panel study that allows us to learn about the characteristics of the penumbras of politically relevant groups such as gay people, the unemployed, or recent immigrants. Our study reveals major and systematic differences in the penumbras of various social groups, even ones of similar size. Moreover, we find evidence that entering a group's penumbra is associated with a change in attitude on group-related policy questions. Taken together, our findings suggest that penumbras are pertinent for understanding variation in the political standing of different groups in society.


Asunto(s)
Política , Opinión Pública , Red Social , Femenino , Humanos , Masculino
2.
J Biomed Opt ; 18(3): 036011, 2013 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-23515866

RESUMEN

First measurements of biomedical imaging using quantum cascade lasers (QCL) are presented. We report spectroscopic imaging of serum proteins using QCLs as an example for monitoring surface biocontamination. We found that dry smears of human serum can be spectroscopically imaged, identified, and quantified with high sensitivity and specificity. The core parts of the imaging platform consist of optically multiplexing three QCLs and an uncooled microbolometer camera. We show imaging of human serum proteins at 6.1, 9.25, and 9.5 µm QCLs with high sensitivity and specificity. The sensitivity limit of 3 µg/cm² of the human serum spot was measured at an S/N=3.The specificity of human serum detection was measured at 99% probability at a threshold of 77 µg/cm². We anticipate our imaging technique to be a starting point for more sophisticated biomolecular diagnostic applications.


Asunto(s)
Proteínas Sanguíneas/química , Láseres de Semiconductores , Imagen Molecular/métodos , Espectrofotometría Infrarroja/métodos , Proteínas Sanguíneas/análisis , Humanos , Sensibilidad y Especificidad , Espectrofotometría Infrarroja/instrumentación
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