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1.
Worldviews Evid Based Nurs ; 16(5): 362-370, 2019 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-31328379

RESUMEN

BACKGROUND: The importance of change-of-shift handoffs in maintaining patient safety has been well demonstrated. Change-of-shift handoff is an important source of data used in surveillance, a nursing intervention aimed at identifying and preventing complications. Surveillance requires the nurse to acquire, process, and synthesize information (cues) encountered during patient care. Interruptions in handoff have been observed but there is a gap in the evidence concerning how interruptions during nurse-to-nurse handoff impact the change-of-shift handoff process. AIMS: To describe registered nurses' perceptions of interruptions experienced during change-of-shift handoff at the bedside in critical care units and analyze the number, type, and source of interruptions during change-of-shift handoff at the bedside. METHODS: An exploratory descriptive design was used. One hundred nurse-to-nurse handoffs were observed, and four focus groups were conducted. Observation data were analyzed with descriptive statistics and quantitative content analysis. Focus group data were analyzed with qualitative content analysis. RESULTS AND FINDINGS: Of the 1,196 interruptions observed, 800 occurred in the communication between the two nurses involved in the handoff. Over 80% (645) of these interruptions were from the nurse receiving handoff and included questions or clarification of information received. About half of the nurses reported that interruptions occurred during handoff. Focus group findings revealed that whether or not something is an interruption is determined by the individual nurse's appraisal of value added to their knowledge of the patient and/or plan of care at the time of handoff. LINKING EVIDENCE TO ACTION: Interruptions during handoff are evaluated as useful or disruptive based on the value to the nurse at the time. Strict structuring or mandating of handoff elements may limit nurses' ability to communicate information deemed most relevant to the care of a specific unique patient.


Asunto(s)
Relaciones Interprofesionales , Enfermeras y Enfermeros/psicología , Pase de Guardia/normas , Percepción , Práctica Clínica Basada en la Evidencia/métodos , Grupos Focales/métodos , Humanos , Minnesota , Pase de Guardia/tendencias
2.
Matern Child Health J ; 22(10): 1430-1435, 2018 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-29600473

RESUMEN

Objectives Studies examining risk factors for preterm birth (PTB) such as psychosocial stress are often focused on women with a history of PTB; however, most preterm babies are born to women with no history of preterm birth. Our objective was to determine if the relationship between psychosocial stress and PTB is altered by parity. Non-Hispanic black (NHB) women have increased psychosocial stress and PTB; therefore, we further aimed to determine if race alters the relationship between psychosocial stress, parity, and PTB. Methods We performed a secondary analysis of the Healthy Pregnancy, Healthy Baby Study comparing pregnant women who were primiparous (first pregnancy), multiparous with history of preterm birth, or multiparous with history of term birth. Perceived stress, perceived racism, interpersonal support, John Henryism and self-efficacy were measured using validated instruments. Logistic regression was used to model the effect of psychosocial stress on PTB stratified by parity and race. Results The analysis entire cohort included 1606 subjects, 426 were primiparous, 268 had a history of presterm birth, and 912 had a history of term birth. In women with a history of term birth, higher self-efficacy was associated with lower odds of spontaneous PTB, and this association was amplified in NHB women. In women with a history of spontaneous PTB, John Henryism Active Coping was associated with lower odds of spontaneous PTB in the index pregnancy. Conclusions for Practice The relationship between psychosocial stress and PTB may be mediated by parity and race.


Asunto(s)
Etnicidad/estadística & datos numéricos , Paridad , Nacimiento Prematuro/etnología , Grupos Raciales/estadística & datos numéricos , Estrés Psicológico/etnología , Adulto , Femenino , Humanos , Recien Nacido Prematuro , Embarazo , Nacimiento Prematuro/etiología , Apoyo Social , Estrés Psicológico/psicología
3.
Matern Child Health J ; 20(6): 1103-13, 2016 06.
Artículo en Inglés | MEDLINE | ID: mdl-27107859

RESUMEN

Objectives Domains of psychosocial health have been separately connected to pregnancy outcomes. This study explores the relationship between five domains of psychosocial health and their joint association with prenatal health and pregnancy outcomes. Methods Women from a prospective cohort study in Durham, North Carolina were clustered based on measures of paternal support, perceived stress, social support, depression, and self-efficacy. Clusters were constructed using the K-means algorithm. We examined associations between psychosocial health and maternal health correlates, pregnancy intention, and pregnancy outcomes using Chi square tests and multivariable models. Results Three psychosocial health profiles were identified, with the first (Resilient; n = 509) characterized by low depression and perceived stress and high interpersonal support, paternal support, and self-efficacy. The second profile (Vulnerable; n = 278) was marked by high depression and perceived stress, and low interpersonal support, paternal support, and self-efficacy. The third profile (Moderate, n = 526) fell between the other profiles on all domains. Health correlates, pregnancy intention, and pregnancy outcomes varied significantly across profiles. Women with the vulnerable profile were more likely to have risky health correlates, have an unintended pregnancy, and deliver preterm. Women with the resilient profile had better birth outcomes and fewer deleterious health correlates, preconception and prenatally. Conclusions We posit that vulnerable psychosocial health, deleterious health correlates, and the stress which often accompanies pregnancy may interact to magnify risk during pregnancy. Identifying and intervening with women experiencing vulnerable psychosocial health may improve outcomes for women and their children.


Asunto(s)
Depresión , Intención , Resultado del Embarazo/psicología , Embarazo no Planeado/psicología , Mujeres Embarazadas/psicología , Apoyo Social , Estrés Psicológico , Adulto , Análisis por Conglomerados , Depresión/etiología , Depresión/prevención & control , Femenino , Conductas Relacionadas con la Salud , Humanos , North Carolina , Embarazo , Complicaciones del Embarazo/psicología , Embarazo no Deseado/psicología , Estudios Prospectivos , Psicología , Factores de Riesgo , Factores Socioeconómicos , Estrés Psicológico/complicaciones , Estrés Psicológico/etiología
4.
J Wound Ostomy Continence Nurs ; 41(2): 181-6, 2014.
Artículo en Inglés | MEDLINE | ID: mdl-24595182

RESUMEN

BACKGROUND: Surgical wounds are at increased risk of infection when left open to heal through secondary intention; they increase length of hospital stay, hospital costs, readmission rates, and patient morbidity. New technologies and methods of treating acute and chronic wounds are emerging. Two recent developments for the treatment of open wounds are noncontact low-frequency ultrasound (NCLFU) treatment and negative pressure wound therapy (NPWT). METHODS: This case series reports findings from 4 hospitalized patients with complex conditions who underwent colorectal surgery resulting in open abdominal wounds. The wounds were treated with NCLFU in combination with NPWT. Data were collected via retrospective review of medical records. RESULTS: After concurrent treatment with NPWT (range, 13-18 days) and NCLFU (range, 5-9 treatments), wound areas in these 4 cases were reduced by 4.5% to 37% and wound volume decreased by 17% to 62%. Granulation tissue increased in the open tissue areas in all patients. In addition, 3 of the cases received a mesh graft. CONCLUSIONS: Combination treatment with NPWT and NCLFU therapy with or without sharp debridement enhanced wound healing in the open abdominal wounds of these 4 patients.


Asunto(s)
Abdomen/cirugía , Terapia de Presión Negativa para Heridas/métodos , Terapia por Ultrasonido/métodos , Cicatrización de Heridas/fisiología , Adulto , Femenino , Humanos , Persona de Mediana Edad
5.
Medsurg Nurs ; 23(2): 111-6, 2014.
Artículo en Inglés | MEDLINE | ID: mdl-24933789

RESUMEN

Discharge planning rounds done at the bedside is an effective patient-centered approach to discharge planning and does not take any longer than traditional rounds apart from the patient and caregiver. Bedside rounds may decrease patient utilization of health care resources after discharge.


Asunto(s)
Alta del Paciente , Atención Dirigida al Paciente/métodos , Adulto , Anciano , Investigación en Enfermería Clínica , Estudios de Factibilidad , Femenino , Humanos , Masculino , Persona de Mediana Edad , Readmisión del Paciente/estadística & datos numéricos , Atención Dirigida al Paciente/organización & administración
6.
J Clin Transl Sci ; 8(1): e121, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-39345710

RESUMEN

Multisector stakeholders, including, community-based organizations, health systems, researchers, policymakers, and commerce, increasingly seek to address health inequities that persist due to structural racism. They require accessible tools to visualize and quantify the prevalence of social drivers of health (SDOH) and correlate them with health to facilitate dialog and action. We developed and deployed a web-based data visualization platform to make health and SDOH data available to the community. We conducted interviews and focus groups among end users of the platform to establish needs and desired platform functionality. The platform displays curated SDOH and de-identified and aggregated local electronic health record data. The resulting Social, Environmental, and Equity Drivers (SEED) Health Atlas integrates SDOH data across multiple constructs, including socioeconomic status, environmental pollution, and built environment. Aggregated health prevalence data on multiple conditions can be visualized in interactive maps. Data can be visualized and downloaded without coding knowledge. Visualizations facilitate an understanding of community health priorities and local health inequities. SEED could facilitate future discussions on improving community health and health equity. SEED provides a promising tool that members of the community and researchers may use in their efforts to improve health equity.

7.
J Urban Health ; 90(5): 857-71, 2013 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-22907713

RESUMEN

The determinants that underlie a healthy or unhealthy pregnancy are complex and not well understood. We assess the relationship between the built environment and maternal psychosocial status using directly observed residential neighborhood characteristics (housing damage, property disorder, tenure status, vacancy, security measures, violent crime, and nuisances) and a wide range of psychosocial attributes (interpersonal support evaluation list, self-efficacy, John Henryism active coping, negative partner support, Perceived Stress Scale, perceived racism, Center for Epidemiologic Studies-Depression) on a pregnant cohort of women living in the urban core of Durham, NC, USA. We found some associations between built environment characteristic and psychosocial health varied by exposure categorization approach, while others (residence in environments with more rental property is associated with higher reported active coping and negative partner support) were consistent across exposure categorizations. This study outlines specific neighborhood characteristics that are modifiable risk markers and therefore important targets for increased research and public health intervention.


Asunto(s)
Ambiente , Salud Mental , Embarazo/psicología , Características de la Residencia/estadística & datos numéricos , Población Urbana , Adaptación Psicológica , Adolescente , Adulto , Crimen/estadística & datos numéricos , Femenino , Humanos , Resultado del Embarazo/epidemiología , Racismo/psicología , Autoeficacia , Medio Social , Factores Socioeconómicos , Estrés Psicológico/epidemiología , Salud de la Mujer , Adulto Joven
8.
Urol Nurs ; 33(1): 9-14, 37; quiz 14, 2013.
Artículo en Inglés | MEDLINE | ID: mdl-23556373

RESUMEN

Radical prostatectomy is the most common cause of urinary incontinence in males. Urinary slings are a relatively new treatment option for men. This article describes two urinary sling procedures as possible surgical approaches for incontinence in men.


Asunto(s)
Enfermería Perioperatoria/métodos , Cabestrillo Suburetral , Incontinencia Urinaria de Esfuerzo/enfermería , Incontinencia Urinaria de Esfuerzo/cirugía , Procedimientos Quirúrgicos Urológicos Masculinos/enfermería , Educación Continua en Enfermería , Humanos , Masculino , Hiperplasia Prostática/enfermería , Hiperplasia Prostática/cirugía , Procedimientos Quirúrgicos Urológicos Masculinos/métodos
9.
Urol Nurs ; 33(6): 289-98, 2013.
Artículo en Inglés | MEDLINE | ID: mdl-24592522

RESUMEN

In a nonrandomized prospective study, significant decreases in patient anxiety with home urinary catheter management and in length of stay were reported when patients attended the preoperative prostatectomy class with standard postoperative education versus standard postoperative education.


Asunto(s)
Educación del Paciente como Asunto/métodos , Enfermería Perioperatoria/métodos , Prostatectomía/enfermería , Cateterismo Urinario/enfermería , Cateterismo Urinario/psicología , Ansiedad/enfermería , Humanos , Masculino , Persona de Mediana Edad , Alta del Paciente , Estudios Prospectivos , Encuestas y Cuestionarios
10.
JAMA Netw Open ; 6(12): e2348914, 2023 12 01.
Artículo en Inglés | MEDLINE | ID: mdl-38127347

RESUMEN

Importance: Studies elucidating determinants of residential neighborhood-level health inequities are needed. Objective: To quantify associations of structural racism indicators with neighborhood prevalence of chronic kidney disease (CKD), diabetes, and hypertension. Design, Setting, and Participants: This cross-sectional study used public data (2012-2018) and deidentified electronic health records (2017-2018) to describe the burden of structural racism and the prevalence of CKD, diabetes, and hypertension in 150 residential neighborhoods in Durham County, North Carolina, from US census block groups and quantified their associations using bayesian models accounting for spatial correlations and residents' age. Data were analyzed from January 2021 to May 2023. Exposures: Global (neighborhood percentage of White residents, economic-racial segregation, and area deprivation) and discrete (neighborhood child care centers, bus stops, tree cover, reported violent crime, impervious areas, evictions, election participation, income, poverty, education, unemployment, health insurance coverage, and police shootings) indicators of structural racism. Main Outcomes and Measures: Outcomes of interest were neighborhood prevalence of CKD, diabetes, and hypertension. Results: A total of 150 neighborhoods with a median (IQR) of 1708 (1109-2489) residents; median (IQR) of 2% (0%-6%) Asian residents, 30% (16%-56%) Black residents, 10% (4%-20%) Hispanic or Latino residents, 0% (0%-1%) Indigenous residents, and 44% (18%-70%) White residents; and median (IQR) residential income of $54 531 ($37 729.25-$78 895.25) were included in analyses. In models evaluating global indicators, greater burden of structural racism was associated with greater prevalence of CKD, diabetes, and hypertension (eg, per 1-SD decrease in neighborhood White population percentage: CKD prevalence ratio [PR], 1.27; 95% highest density interval [HDI], 1.18-1.35; diabetes PR, 1.43; 95% HDI, 1.37-1.52; hypertension PR, 1.19; 95% HDI, 1.14-1.25). Similarly in models evaluating discrete indicators, greater burden of structural racism was associated with greater neighborhood prevalence of CKD, diabetes, and hypertension (eg, per 1-SD increase in reported violent crime: CKD PR, 1.15; 95% HDI, 1.07-1.23; diabetes PR, 1.20; 95% HDI, 1.13-1.28; hypertension PR, 1.08; 95% HDI, 1.02-1.14). Conclusions and Relevance: This cross-sectional study found several global and discrete structural racism indicators associated with increased prevalence of health conditions in residential neighborhoods. Although inferences from this cross-sectional and ecological study warrant caution, they may help guide the development of future community health interventions.


Asunto(s)
Diabetes Mellitus , Hipertensión , Insuficiencia Renal Crónica , Humanos , Estudios Transversales , Teorema de Bayes , Prevalencia , Racismo Sistemático , Enfermedad Crónica , Hipertensión/epidemiología
11.
Medsurg Nurs ; 21(3): 140-4; quiz 145, 2012.
Artículo en Inglés | MEDLINE | ID: mdl-22866433

RESUMEN

UNLABELLED: Nurse-to-nurse beside handoff allows the oncoming nurse to visualize the patient and ask questions of the previous nurse. It encourages pateints to be involved actively in their care and allows standardized communication between nursing shifts. BACKGROUND: Patient handoff between nurses at shift change has been an important process in clinical nursing practice, allowing nurses to exchange necessary patient information to ensure continuity of care and patient safety. Bedside handoff allows the patient the ability to contribute to his or her plan of care. It also allows the oncoming nurse an opportunity to visualize the patient and ask questions. This is critical in meeting the Joint Commission's 2009 National Patient Safety Goals. It encourages patients to be involved actively in their care and it implements standardized handoff communication between nursing shifts. Bedside handoff promotes patient safety and allows an opportunity for patients to correct misconceptions. METHODS: A convenience sample of 60 patients was enrolled, 30 before the practice change and 30 after the change. All nursing staff were invited to participate. Both patients and staff were given self-designed surveys before and after the practice change. RESULTS: Fifteen nurses with a mean of 2 years in the profession completed the pre- and post-survey. A majority of staff were not satisfied with the current shift change report, but statistical improvement was achieved after the practice change. Also, statistical improvement was achieved with patients' satisfaction with involvement in their plan of care. CONCLUSIONS: Use of bedside nursing handoff promotes staff accountability, two-person IV medication reconciliation, and patient satisfaction.


Asunto(s)
Continuidad de la Atención al Paciente , Relaciones Interprofesionales , Atención de Enfermería/organización & administración , Evaluación de Procesos y Resultados en Atención de Salud , Planificación de Atención al Paciente/organización & administración , Seguridad del Paciente , Actitud del Personal de Salud , Femenino , Humanos , Masculino , Satisfacción del Paciente , Estados Unidos
12.
Am J Crit Care ; 31(3): 181-188, 2022 05 01.
Artículo en Inglés | MEDLINE | ID: mdl-35466352

RESUMEN

BACKGROUND: Nursing handoff is a communication activity with a high risk for loss or omission of information. Efforts to improve handoffs include standardization of the processes and content of handoff communications. OBJECTIVES: To examine nurses' perspectives on the structure and organization of change-of-shift handoffs. METHODS: A qualitative descriptive approach was used to conduct a secondary analysis of focus group data. Thirty-four nurses from 4 critical care units participated in focus groups. RESULTS: Three themes emerged: handoff elements are defined by practice and culture; a clear, consistent, identified structure supports handoff; and personal preferences can disrupt handoff. CONCLUSIONS: A standardized approach to handoff based on unit and organizational needs will be more successful than a broad mandate of content and organization. Individual preference is prevalent and strongly influences the information conveyed and the structure of handoff communication.


Asunto(s)
Enfermeras y Enfermeros , Pase de Guardia , Comunicación , Práctica Clínica Basada en la Evidencia , Grupos Focales , Humanos
13.
J Contin Educ Nurs ; 42(5): 197-8, 2011 May.
Artículo en Inglés | MEDLINE | ID: mdl-21534509

RESUMEN

This is the second part of a three-part series describing how an enhanced recovery clinical pathway uses a multidisciplinary team to reduce postoperative stress and complications, improve recovery, and decrease hospital length of stay without affecting patient safety for patients undergoing colorectal surgery. Last month, patient education and discharge planning were discussed. This part discusses multimodal analgesia and standardized postoperative nausea and vomiting prophylaxis. Next month, fluids, diet, tubes and drains, and early mobilization will be discussed.


Asunto(s)
Cirugía Colorrectal/enfermería , Vías Clínicas , Enfermería Basada en la Evidencia/organización & administración , Enfermería Perioperatoria/métodos , Humanos
14.
J Contin Educ Nurs ; 42(4): 152-3, 2011 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-21462907

RESUMEN

This is the first part of a three-part series describing how an enhanced recovery clinical pathway uses a multidisciplinary team to reduce postoperative stress and complications, improve recovery, and decrease hospital length of stay without affecting patient safety for patients undergoing colorectal surgery. This part discusses patient education and discharge planning. Next month, pain and postoperative nausea and vomiting will be discussed.


Asunto(s)
Colon/cirugía , Alta del Paciente , Educación del Paciente como Asunto , Cuidados Posoperatorios/enfermería , Recto/cirugía , Enfermería Basada en la Evidencia , Humanos
15.
J Contin Educ Nurs ; 42(6): 246-7, 2011 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-21627056

RESUMEN

This is the third part of a three-part series describing how an enhanced recovery clinical pathway uses a multidisciplinary team to reduce postoperative stress and complications, improve recovery, and decrease hospital length of stay without affecting patient safety for patients undergoing colorectal surgery. Last month, multimodal analgesia and standardized postoperative nausea and vomiting prophylaxis were discussed. This part discusses fluids, diet, tubes and drains, and early mobilization.


Asunto(s)
Cirugía Colorrectal/enfermería , Vías Clínicas , Enfermería Basada en la Evidencia/métodos , Enfermería Perioperatoria/métodos , Cuidados Posoperatorios/métodos , Humanos , Recuperación de la Función
16.
J Contin Educ Nurs ; 42(8): 347-57; quiz 358-9, 2011 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-21332106

RESUMEN

BACKGROUND: This study was undertaken to determine whether interdisciplinary high-fidelity simulation training improves group cohesion in nurse-physician teams. In addition, perceptions of collaboration and satisfaction with patient care decisions were measured in nurse-physician participants. METHODS: Clinical scenarios relevant to the general surgical urology inpatient unit were conducted in an interdisciplinary high-fidelity simulation center. Participants included physicians and staff nurses. RESULTS: Participants reported a positive shift in group cohesion over time. In addition, the results suggested a positive shift in perceptions of collaboration and satisfaction with patient care decisions over time. The youngest participants (Millennial Generation, born in the 1980s and 1990s) showed the most significant growth in response to the training. CONCLUSION: This study provides evidence of benefits of high-fidelity simulation that extend beyond the training. Simulation training may be a strategy to build and strengthen relationships across nurse-physician teams. In addition, this type of training may positively affect collaboration and satisfaction with patient care decisions. When data were analyzed by generational grouping, the most significant growth occurred in the Millennial Generation participants. These influences need to be explored further.


Asunto(s)
Educación Continua en Enfermería/métodos , Cuerpo Médico de Hospitales/educación , Personal de Enfermería en Hospital/educación , Grupo de Atención al Paciente , Simulación de Paciente , Adulto , Educación Continua en Enfermería/organización & administración , Femenino , Humanos , Masculino , Persona de Mediana Edad , Investigación en Evaluación de Enfermería , Desarrollo de Personal/métodos , Desarrollo de Personal/organización & administración
17.
Public Health Rep ; 125(4): 579-87, 2010.
Artículo en Inglés | MEDLINE | ID: mdl-20597458

RESUMEN

OBJECTIVES: To better understand disparities in pregnancy outcomes, we analyzed data from North Carolina to determine how the pattern of maternal hypertensive disorders differs among non-Hispanic white (NHW), non-Hispanic black (NHB), and Hispanic women across the range of maternal ages. In addition, we explored whether rates of poor birth outcomes, including low birthweight (LBW) and preterm birth (PTB), among hypertensive women differed by race. METHODS: We restricted our analyses to births occurring between 1994 and 2003, constructing six five-year maternal age categories: 15-19 years, 20-24 years, 25-29 years, 30-34 years, 35-39 years, and 40-44 years. We used logistic regression to determine the relative contribution of race and age to incidence of maternal hypertension. All analyses controlled for the standard covariates of maternal education, marital status, and tobacco use. To assess the impact of maternal hypertension on birth outcomes, we limited the dataset to women with any hypertensive disorder and used linear regression to determine how particular race-age combinations affected outcomes. We also used logistic regression to find out how particular race-age combinations affected the likelihood of LBW and PTB. RESULTS: The risk of hypertension differed by race, with NHB women exhibiting the highest risk and Hispanic women the lowest risk. Further, rates of hypertension increased with age. Among hypertensive women, pregnancy outcomes differed by race and age, with NHB women having the poorest outcomes (i.e., LBW and PTB) and age exhibiting a dose-response relationship in PTB and very PTB. CONCLUSIONS: Patterns of maternal hypertension and subsequent outcomes are important contributors to persistent disparities in pregnancy outcomes.


Asunto(s)
Disparidades en el Estado de Salud , Hipertensión/etnología , Complicaciones Cardiovasculares del Embarazo/etnología , Resultado del Embarazo/etnología , Adolescente , Adulto , Negro o Afroamericano/estadística & datos numéricos , Femenino , Hispánicos o Latinos/estadística & datos numéricos , Humanos , Hipertensión/epidemiología , Hipertensión Inducida en el Embarazo/epidemiología , Hipertensión Inducida en el Embarazo/etnología , Mortalidad Infantil/etnología , Recién Nacido de Bajo Peso , Recién Nacido , Modelos Logísticos , Edad Materna , North Carolina/epidemiología , Embarazo , Complicaciones Cardiovasculares del Embarazo/epidemiología , Nacimiento Prematuro/etnología , Población Blanca/estadística & datos numéricos , Adulto Joven
18.
J Clin Transl Sci ; 5(1): e13, 2020 Jun 23.
Artículo en Inglés | MEDLINE | ID: mdl-33948239

RESUMEN

INTRODUCTION: Electronic health record (EHR) data have emerged as an important resource for population health and clinical research. There have been significant efforts to leverage EHR data for research; however, given data security concerns and the complexity of the data, EHR data are frequently difficult to access and use for clinical studies. We describe the development of a Clinical Research Datamart (CRDM) that was developed to provide well-curated and easily accessible EHR data to Duke University investigators. METHODS: The CRDM was designed to (1) contain most of the patient-level data elements needed for research studies; (2) be directly accessible by individuals conducting statistical analyses (including Biostatistics, Epidemiology, and Research Design (BERD) core members); (3) be queried via a code-based system to promote reproducibility and consistency across studies; and (4) utilize a secure protected analytic workspace in which sensitive EHR data can be stored and analyzed. The CRDM utilizes data transformed for the PCORnet data network, and was augmented with additional data tables containing site-specific data elements to provide additional contextual information. RESULTS: We provide descriptions of ideal use cases and discuss dissemination and evaluation methods, including future work to expand the user base and track the use and impact of this data resource. CONCLUSIONS: The CRDM utilizes resources developed as part of the Clinical and Translational Science Awards (CTSAs) program and could be replicated by other institutions with CTSAs.

19.
Epidemiol Rev ; 31: 67-83, 2009.
Artículo en Inglés | MEDLINE | ID: mdl-19846592

RESUMEN

One of the most persistent disparities in American health status is the pronounced difference in birth outcomes between non-Hispanic black and non-Hispanic white women. Poor pregnancy outcomes have a substantial impact on mortality, morbidity, and health care costs. Increasing evidence indicates that environmental exposures are associated with poor birth outcomes. This paper reviews the latest research on how environmental exposures affect pregnancy outcomes and then discusses how these exposures may be embedded within a context of significant social and host factor stress. The analysis suggests that environmental, social, and host factors are cumulatively stressing non-Hispanic black women and that this cumulative stress may be a cause of the persistent disparities in pregnancy outcomes.


Asunto(s)
Exposición a Riesgos Ambientales/efectos adversos , Disparidades en el Estado de Salud , Resultado del Embarazo , Femenino , Humanos , Recién Nacido de Bajo Peso , Recién Nacido , Embarazo , Salud Pública , Estados Unidos
20.
J Expo Sci Environ Epidemiol ; 25(4): 427-32, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-25073434

RESUMEN

The objectives of this study were to examine cadmium (Cd) levels and relationships to demographics in an observational, prospective pregnancy cohort study in Durham County, North Carolina. Multivariable models were used to compare blood Cd levels across demographic characteristics. The relative risk of having a blood Cd level that exceeds the US national median (0.32 µg/l) was estimated. Overall, >60% of the women had an elevated (>0.32 µg/l) blood Cd level. Controlling for confounding variables, smoking was associated with 21% (95% CI: 15-28%) increased risk for an elevated blood Cd level. High Cd levels were also observed in non-smokers and motivated smoking status-stratified models. Race, age, education, relationship status, insurance status and cotinine level were not associated with risk of elevated Cd levels among smokers; however, older age and higher cotinine levels were associated with elevated Cd levels among non-smokers. Taken together, more than half of pregnant women in this cohort had elevated blood Cd levels. Additionally, among non-smokers, 53% of the women had elevated levels of Cd, highlighting other potential sources of exposure. This study expands on the limited data describing Cd levels in pregnant populations and highlights the importance of understanding Cd exposures among non-smokers. Given the latent health risks of both smoking and Cd exposure, this study further highlights the need to biomonitor for exposure to toxic metals during pregnancy among all women of child-bearing age.


Asunto(s)
Cadmio/sangre , Monitoreo del Ambiente , Contaminantes Ambientales/sangre , Exposición Materna/estadística & datos numéricos , Embarazo/sangre , Adolescente , Adulto , Femenino , Humanos , Persona de Mediana Edad , Análisis Multivariante , North Carolina , Estudios Prospectivos , Factores de Riesgo , Adulto Joven
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