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1.
Int J Surg ; 110(5): 2535-2544, 2024 May 01.
Artículo en Inglés | MEDLINE | ID: mdl-38349204

RESUMEN

BACKGROUND: The impact of quality improvement initiatives program (QIP) on coronary artery bypass grafting surgery (CABG) remains scarce, despite improved outcomes in other surgical areas. This study aims to evaluate the impact of a package of QIP on mortality rates among patients undergoing CABG. MATERIALS AND METHODS: This prospective cohort study utilized data from the multicenter database Registro Paulista de Cirurgia Cardiovascular II (REPLICCAR II), spanning from July 2017 to June 2019. Data from 4018 isolated CABG adult patients were collected and analyzed in three phases: before-implementation, implementation, and after-implementation of the intervention (which comprised QIP training for the hospital team). Propensity Score Matching was used to balance the groups of 2170 patients each for a comparative analysis of the following outcomes: reoperation, deep sternal wound infection/mediastinitis ≤30 days, cerebrovascular accident, acute kidney injury, ventilation time >24 h, length of stay <6 days, length of stay >14 days, morbidity and mortality, and operative mortality. A multiple regression model was constructed to predict mortality outcomes. RESULTS: Following implementation, there was a significant reduction of operative mortality (61.7%, P =0.046), as well as deep sternal wound infection/mediastinitis ( P <0.001), sepsis ( P =0.002), ventilation time in hours ( P <0.001), prolonged ventilation time ( P =0.009), postoperative peak blood glucose ( P <0.001), total length of hospital stay ( P <0.001). Additionally, there was a greater use of arterial grafts, including internal thoracic ( P <0.001) and radial ( P =0.038), along with a higher rate of skeletonized dissection of the internal thoracic artery. CONCLUSIONS: QIP was associated with a 61.7% reduction in operative mortality following CABG. Although not all complications exhibited a decline, the reduction in mortality suggests a possible decrease in failure to rescue during the after-implementation period.


Asunto(s)
Puente de Arteria Coronaria , Mejoramiento de la Calidad , Humanos , Puente de Arteria Coronaria/mortalidad , Puente de Arteria Coronaria/efectos adversos , Femenino , Masculino , Estudios Prospectivos , Anciano , Persona de Mediana Edad , Tutoría , Complicaciones Posoperatorias/mortalidad , Complicaciones Posoperatorias/epidemiología , Puntaje de Propensión
2.
World Neurosurg ; 87: 663.e1-8, 2016 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-26585725

RESUMEN

OBJECTIVE: Infection of a subdural hematoma is an unusual cause of subdural empyema, with fewer than 50 cases reported in the literature. The appropriate surgical option for this entity has not been determined because of its rarity. We present a case report of a post-traumatic subdural hematoma infected with Escherichia coli that was successfully treated with craniotomy. In addition, we performed a PubMed search to comprehensively illustrate the causative organism, source of infection, clinical picture, surgical treatment, and outcome for this condition. This article presents an update on the condition. CASE DESCRIPTION: A 55-year-old man was admitted to our hospital complaining of headache, seizure, and urinary incontinence. He had a history of alcoholism and several hospitalizations for mild head trauma. Neuroimaging studies revealed a chronic hematic collection in the left frontal-parietal region. Laboratory tests showed increased C-reactive protein levels. In addition, surgical results revealed an infected subdural hematoma. A bacterial culture of the purulent specimen identified E. coli. In view of the urinary complaint and leukocyturia, the cause of the infected subdural hematoma was postulated as a urinary tract infection. CONCLUSIONS: Infected subdural hematoma is an unusual disorder. We must keep in mind the possibility of this complication when seeing a patient who presents with any of the 3 most common symptoms in this review. In these patients, craniotomy should be the method of surgical drainage, especially in adults. It ensures maximal drainage of the loculated pus and allows the total removal of the infected hematoma capsule.


Asunto(s)
Infecciones del Sistema Nervioso Central/etiología , Infecciones del Sistema Nervioso Central/terapia , Hematoma Intracraneal Subdural/complicaciones , Hematoma Intracraneal Subdural/terapia , Antibacterianos/uso terapéutico , Infecciones del Sistema Nervioso Central/tratamiento farmacológico , Infecciones por Escherichia coli/terapia , Hematoma Intracraneal Subdural/tratamiento farmacológico , Humanos , Masculino , Persona de Mediana Edad
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