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BACKGROUND: The use of self-expanding biodegradable prosthesis treatment of refractory benign stenosis is still undefined. OBJECTIVE: To determine the utility and safety of biodegradable polydioxanone prostheses as treatment of gastrointestinal tract refractory benign strictures. METHODS: Consecutive patients diagnosed with refractory benign stricture of gastrointestinal tract following Kochman's criteria were included. The type of stenosis were anastomotic (n = 5), peptic (n = 1), post-radiotherapy (n = 1) and they were located in proximal esophagus-hypofarynge (n = 2), esophagus medium (n = 1), distal esophagus (n = 2) and rectum (n = 2). The prosthesis was placed under endoscopic and fluoroscopic control under conscious sedation with propofol. RESULTS: Seven patients (8 prosthesis) were included. Mean patient age was 49 years-old (range: 37-70). Insertion prosthesis was successful in all cases. Distal migration of prosthesis was observed in both rectal stenosis and was the indication of a second prosthesis placement in one case. At the end of follow-up (median follow-up 30 weeks for esophageal stricture, 33 weeks for rectal stricture) 5 patients remained asymptomatic. Eighty per cent of patients with esophageal stenosis showed partial and transient re-stenosis due to hyperplastic reaction during the degradation of the prosthesis, with transient dysphagia in two patients resolved medically. Complete prosthesis degradation was confirmed by endoscopy in all cases. CONCLUSIONS: The use of self-expanding biodegradable polydioxanone prosthesis is a safe and utile therapeutic option for refractory benign gastrointestinal stenosis.
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Estenosis Esofágica/terapia , Prótesis e Implantes , Implantación de Prótesis/métodos , Implantes Absorbibles , Adulto , Anciano , Sedación Consciente , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Polidioxanona , Enfermedades del Recto/terapiaRESUMEN
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Humanos , Masculino , Adulto , Enfermedad de Crohn/complicaciones , Inmunosupresores/efectos adversos , Infecciones Oportunistas/diagnóstico , Infecciones por Citomegalovirus/diagnóstico , Citomegalovirus/patogenicidadRESUMEN
Objetivos. Estudiar la prevalencia de la infección por Helicobacter pylori en el personal sanitario de dos Servicios hospitalarios del Hospital Clínico San Cecilio de Granada. Casuística. Se estudian 60 personas; 30 de ellas del Servicio de Aparato Digestivo (personal facultativo y no facultativo ) y otras 30 de personal de los Servicios de Oftalmología y endocrinología. Métodos. Se empleo el test del aliento con urea marcada con C13 (no radiactivo). UB test. Resultados: En el personal del Servicio Digestivo la posibilidad del test fue del 65,5% (19 casos) y en los Servicios no digestivos del 73% (19 casos); no hubo diferencias estadísticamente significativas entre ellos. Según el tipo de personal las proporciones fueron en el Servicio de Digestivo: médicos adjuntos 68,4% (13 casos+), médicos residentes, 50% (7 casos+) ayudantes técnicos sanitarios 75% (9 casos+) y personal auxiliar 90% (9 casos+). Hubo diferencias estadísticas significativas (p<0.05) entre el personal auxiliar y los médicos adjuntos y personal auxiliar y médicos residentes. Conclusiones. La prevalencia de la infección por Helicobacter pylori en el Servicio de Aparato Digestivo es del 69,1% similar a la de otros servicios del Hospital. El personal del Servicio de Aparato Digestivo es el más expuesto a la infección por Helycobacter pylori, que es el más expuesto al contacto directo con los pacientes
Objetives: To study the infection due to Helicobacter pylori among the health personnel in two hospital services at the University Hospital San Cecilio in Granada, Spain.Casuistry. A total of 60 individuals were studied; 30 of them belonged to the Gastroenterology Unit (medical and nonmedical staff) and 30 belonged to the Endocinology and the Ophthalmology Units. Methods. The Carbon 13- labeled urea breath test (non radioactive) (C-13 UBT) was used. Results. Among the staff from the Gastroenterology Unit, the positive result of the test was 65% (19 cases), while it was 73% among the personnel from the other two Units (19 cases). There were no statistically significant differences among them. In the Gastroenterology Unit, the ratios were as follows: attending physicians, 68% (13 cases +); resident physicians , 50% (7 cases +); nursing assistant, 75% (9 cases +); and assistant staff, 90% (9 cases +). There were statistically significant differences (p< 0.05) between the assistant staff and the attending physicians and the assistant staff and the resident physicians. Conclusions. Prevalence of Helicobacter pylori infection in the Gastroenterology Unit is similar to other hospitals (69.1%). The assistant staff in the Gastroenterology Unit is the most exposed to infection by Helicobacter pylori due to the direct contact with the patient
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Humanos , Helicobacter pylori/aislamiento & purificación , Infecciones por Helicobacter/epidemiología , Personal de Salud/estadística & datos numéricos , Departamentos de Hospitales/estadística & datos numéricos , Transmisión de Enfermedad Infecciosa de Paciente a Profesional/estadística & datos numéricosRESUMEN
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Humanos , Trasplante de Hígado/estadística & datos numéricos , Donantes de Tejidos , Obtención de Tejidos y Órganos , Selección de PacienteRESUMEN
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