RESUMEN
Coronavirus infection (SARS-CoV-2), is a pandemic disease declared by the World Health Organization (WHO). This disease reports a high risk of contagion, especially by the transmission of aerosols in health care workers. In this scenario, aerosol exposure is increased in various procedures related to the airway, lungs, and pleural space. For this reason, it is important to have recommendations that reduce the risk of exposure and infection with COVID-19. In this document, a team of international specialists in interventional pulmonology elaborated a series of recommendations, based on the available evidence to define the risk stratification, diagnostic methods and technical considerations on procedures such as bronchoscopy, tracheostomy, and pleural procedures among others. As well as the precautions to reduce the risk of contagion when carrying out pulmonary interventions.
Asunto(s)
Humanos , Transmisión de Enfermedad Infecciosa de Paciente a Profesional/prevención & control , Infecciones por Coronavirus/prevención & control , Pandemias , Control de InfeccionesRESUMEN
This review of the immunogenetics of cord blood transplantation attempts to highlight the connections between classical studies and conclusions of the tissue transplantation field as a scholarly endeavor, exemplified by the work of Professor Hoecker, with the motivations and some recent and key results of clinical cord blood transplantation. The authors review the evolution of understanding of transplantation biology and find that the results of the application of cord blood stem cells to Transplantation Medicine are consistent with the careful experiments of the pioneers in the field, from the results of tumor and normal tissue transplants, histocompatibility immunogenetics, to cell and molecular biology. Recent results of the National Cord Blood Program of the New York Blood Center describe the functioning in cord blood transplantation of factors, well known in transplantation immunogenetics, like the Fl anti-parent effect and the tolerance-like status of donors produced by non-inherited maternal HLA antigens. Consideration of these factors in donor selection strategies can improve the prognosis of transplantation by characterizing "permissibility" in HLA-incompatible transplantation thereby increasing the probability of survival and reducing the likelihood of leukemic relapse.
Asunto(s)
Humanos , Trasplante de Células Madre de Sangre del Cordón Umbilical , Antígenos HLA/genética , Antígenos HLA/inmunología , Histocompatibilidad/inmunología , Fenómenos Inmunogenéticos/inmunología , Inmunología del Trasplante/inmunología , Histocompatibilidad/genética , Fenómenos Inmunogenéticos/genética , Inmunología del Trasplante/genéticaRESUMEN
Prólogo. Historia de la transfusión sanguínea. Fuentes de sangre. La extracción de sangre. Dadores y extracciones especilaes. Conservación de la sangre. Criopreservación de la sangre. Principios báscios de inmunología. Sistema de grupo sanguíneo ABO. Nociones básicas de genética. El sistema RH-HR. Otros sistemas de grupos sanguíneos. Sistema HLA. Terapéutica transfusional: uso racional de la sangre, sus componentes y derivados. Citoferesis: plaquetoferesis y leucoferesis. Plasmaferesis masiva. Reacciones desfavorables de la transfusión. Enfermedades transmisibles. Sustitutos del plasma y de los eritrocitos. Enfermedad hemolítica del recién nacido. Automatización en inmunohematología. Métodos y técnicas. Apéndice. Bibliografía. Glosario. Indice alfabético