RESUMEN
Lymphocyte subpopulations were studied in 18 patients by flow cytometry using monoclonal antibodies before and after surgical repair of the mandible with different transplants. All the transplants used had a stimulating effect on the immunity system. The most marked changes in the time course of immunologic parameters were observed after transplantation of frozen bone and formalin-treated grafts.
Asunto(s)
Trasplante Óseo/inmunología , Procedimientos Quirúrgicos Ortognáticos , Adulto , Femenino , Humanos , Inmunidad Celular , Masculino , Persona de Mediana Edad , Periodo Posoperatorio , Trasplante Autólogo , Trasplante HomólogoRESUMEN
Sixty-three patients with congenital and acquired defects and deformations of facial bones without concomitant diseases were examined. Twenty-eight of them were operated on; auto- and alloplasty was resorted to in 18 patients, and to 10 patients tactivin was administered after common protocols for immunocorrection before or after surgery. Immunologic and clinical studies showed that immunodeficiency states are the most probable causes of postoperative complications following repair surgery on the facial bones. Tactivin normalized the immunity parameters and prevented the development of postoperative complications.