Bio-Inspired Electro-Thermal-Hygro Responsive Rewritable Systems with Temporal/Spatial Control for Environment-Interactive Information Display.

Utilization of rewritable luminescent materials for secure information storage and delivery has long been envisaged to reduce the cost and environmental wastes. However, it remains challenging to realize a temporally/spatially controlled display of the written information, which is crucial for secure information encryption. Here, inspired by bioelectricity-triggered skin pattern switching in cephalopods, an ideal rewritable system consisting of conductive graphene film and carbon dots (CDs) gel with blue-to-red fluorescence-color changes via water-triggered CDs aggregation and re-dispersion is presented. Its rewritability is guaranteed by using water ink to write on the CDs-gel and employing Joule heat of graphene film to evaporate water. Due to the highly controlled electrical stimulus, temporally/spatially controlled display is achieved, enabling on-demand delivery and duration time regulation of the written information. Furthermore, new-concept environment-interactive rewritable system is obtained by integrating sensitive acoustic/optical sensors and multichannel electronic time-delay devices. This work opens unprecedented avenues of rewritable systems and expands potential uses for information encryption/delivery.

Impact of Nd Doping on Electronic, Optical, and Magnetic Properties of ZnO: A GGA + U Study.

The electronic, optical, and magnetic properties of Nd-doped ZnO systems were calculated using the DFT/GGA + U method. According to the results, the Nd dopant causes lattice parameter expansion, negative formation energy, and bandgap narrowing, resulting in the formation of an N-type degenerate semiconductor. Overlapping of the generated impurity and Fermi levels results in a significant trap effect that prevents electron-hole recombination. The absorption spectrum demonstrates a redshift in the visible region, and the intensity increased, leading to enhanced photocatalytic performance. The Nd-doped ZnO system displays ferromagnetic, with FM coupling due to strong spd-f hybridization through magnetic exchange interaction between the Nd-4f state and O-2p, Zn-4s, and Zn-3p states. These findings imply that Nd-doped ZnO may be a promising material for DMS spintronic devices.

Calculation of Mechanical Properties, Electronic Structure and Optical Properties of CsPbX3 (X = F, Cl, Br, I).

We utilized a first-principle density functional theory for a comprehensive analysis of CsPbX3 (X = F, Cl, Br, I) to explore its physical and chemical properties, including its mechanical behavior, electronic structure and optical properties. Calculations show that all four materials have good stability, modulus of elasticity, hardness and wear resistance. Additionally, CsPbX3 demonstrates a vertical electron leap and serves as a semiconductor material with direct band gaps of 3.600 eV, 3.111 eV, 2.538 eV and 2.085 eV. In examining its optical properties, we observed that the real and imaginary components of the dielectric function exhibit peaks within the low-energy range. Furthermore, the dielectric function gradually decreases as the photon energy increases. The absorption spectrum reveals that the CsPbX3 material exhibits the highest UV light absorption, and as X changes (with the increase in atomic radius within the halogen group of elements), the light absorption undergoes a red shift, becoming stronger and enhancing light utilization. These properties underscore the material's potential for application in microelectronic and optoelectronic device production. Moreover, they provide a theoretical reference for future investigations into CsPbX3 materials.

Photoelectrochemical Detection of Exosomal miRNAs by Combining Target-Programmed Controllable Signal Quenching Engineering.

MicroRNAs extracted from exosomes (exosomal miRNAs) have recently emerged as promising biomarkers for early prognosis and diagnosis. Thus, the development of an effective approach for exosomal miRNA monitoring has triggered extensive attention. Herein, a sensitive photoelectrochemical (PEC) biosensing platform is demonstrated for exosomal miRNA assay via the target miRNA-powered λ-exonuclease for the amplification strategy. The metal-organic framework (MOF)-decorated WO3 nanoflakes heterostructure is constructed and implemented as the photoelectrode. Also, a target exosomal miRNA-activatable programmed release nanocarrier was fabricated, which is responsible for signal control. Hemin that acted as the electron acceptor was prior entrapped into the programmed control release nanocarriers. Once the target exosomal miRNAs-21 was introduced, the as-prepared programmed release nanocarriers were initiated to trigger the release of hemin, which enabled the quenching of the photocurrent. Under the optimized conditions, the level of exosomal miRNAs-21 could be accurately tracked ranging from 1 fM to 0.1 µM with a low detection limit of 0.5 fM. The discoveries illustrate the possibility for the rapid and efficient diagnosis and prognosis prediction of diseases based on the detection of exosomal miRNAs-21 and would provide feasible approaches for the fabrication of an efficient platform for clinical applications.

Cu-doped CaFeO3 perovskite oxide as oxygen reduction catalyst in air cathode microbial fuel cells.

Cathode electrocatalyst is quite critical to realize the application of microbial fuel cells (MFCs). Perovskite oxides have been considered as potential MFCs cathode catalysts to replace Pt/C. Herein, Cu-doped perovskite oxide with a stable porous structure and excellent conductivity was successfully prepared through a sol-gel method. Due to the incorporation of Cu, CaFe0.9Cu0.1O3 has more micropores and a larger surface area, which are more conducive to contact with oxygen. Doping Cu resulted in more Fe3+ in B-site and thus enhanced its binding capability to oxygen molecules. The data from electrochemical test demonstrated that the as-prepared catalyst has good conductivity, high stability, and excellent ORR properties. Compared with Pt/C catalyst, CaFe0.9Cu0.1O3 exhibits a lower overpotential, which had an onset potential of 0.195 V and a half-wave potential of -0.224 V, respectively. CaFe0.9Cu0.1O3 displays an outstanding four-electron pathway for ORR mechanism and demonstrates superiors corrosion resistance and stability. The MFC with CaFe0.9Cu0.1O3 has a greater maximum power density (1090 mW m-3) rather than that of Pt/C cathode (970 mW m-3). This work demonstrated CaFe0.9Cu0.1O3 is an economic and efficient cathodic catalyst for MFCs.

Comparison between endoscopic mucosal resection with a cap and endoscopic submucosal dissection for rectal neuroendocrine tumors.

BACKGROUND: The aim of this study is to evaluate and compare the safety and efficacy of endoscopic mucosal resection with a cap (EMR-c) with those of endoscopic submucosal dissection (ESD) for rectal neuroendocrine tumors (R-NETs) ≤ 15 mm in diameter, and to analyze the risk factors of incomplete resection. METHODS: A total of 122 patients who underwent EMR-c or ESD for R-NETs at the Fourth Hospital of Hebei Medical University between February 2007 and December 2020 were invovled in this study. The clinical outcomes of two groups were compared and evaluated. RESULTS: A total of 122 patients with 128 R-NETs underwent endoscopic resection (EMR-c, 80; ESD, 48). In terms of duration of operation, EMR-c was significantly shorter than ESD (p < 0.001). Univariate analysis and multivariate analysis suggested that tumor diameter ≥ 8 mm was an independent risk factor for incomplete resection in patients with R-NETs in this study. CONCLUSIONS: Both EMR-c and ESD were safe and effective treatments for R-NETs ≤ 15 mm in diameter. In addition, tumor diameter ≥ 8 mm was an independent risk factor for incomplete resection.

In situ controllable heterojunction conversion strategy driven by oriented paper-based fluid transfer for human immunoglobulin G detection.

Mercury ions (Hg2+) mediating in situ heterojunction formation strategy based on spatially separated dual working areas was developed to achieve sensitive detection of human immunoglobulin G. To be specific, the complex of antibody, the silicon dioxide, and thymine-rich hairpin DNA were immobilized onto the antigen and antibody-modified electrodes, forming a special sandwich type where T-Hg2+-T structure could accommodate Hg2+. The zinc ions from zinc sulfide (ZnS) photoelectric materials were captured by Hg2+ to convert ZnS to zinc sulfide-mercuric sulfide nanocomposite. Such ion exchange approach with spatially separated working electrodes endowed the sensing platform with lower background interference and high selectivity, which also avoided damage of illumination on biomolecules. In addition, by regulating the ion recognition probe, the protocol could be extended to numerous other fields like clinical diagnosis, environmental monitoring, and public safety.

Aggregation-Induced Emissive Carbon Dots Gels for Octopus-Inspired Shape/Color Synergistically Adjustable Actuators.

Some living organisms such as the octopus have fantastic abilities to simultaneously swim away and alter body color/morphology for disguise and self-protection, especially when there is a threat perception. However, it is still quite challenging to construct artificial soft actuators with octopus-like synergistic shape/color change and directional locomotion behaviors, but such systems could enhance the functions of soft robotics dramatically. Herein, we proposed to utilize unique hydrophobic carbon dots (CDs) with rotatable surficial groups to construct the aggregation-induced emission (AIE) active glycol CDs polymer gel, which could be further employed to be interfacially bonded to an elastomer to produce anisotropic bilayer soft actuator. When putting the actuator on a water surface, glycol spontaneously diffused out from the gel layer to allow water intake, resulting in a color change from a blue dispersion fluorescence to red AIE and a shape deformation, as well as a large surface tension gradient that can promote its autonomous locomotion. Based on these findings, artificial soft swimming robots with octopus-like synergistic shape/color change and directional swimming motion were demonstrated. This study provides an elegant strategy to develop advanced multi-functional bio-inspired intelligent soft robotics.

Recent Advances in Complex Coacervation Design from Macromolecular Assemblies and Emerging Applications.

Coacervation is a process during which a homogeneous aqueous solution undergoes liquid-liquid phase separation, giving rise to two immiscible liquid phases composed of a colloid-rich coacervate phase in equilibrium with a colloid-poor phase simultaneously. Recent attempts to develop complex coacervation from macromolecular self-assemblies have diversified a large group of novel coacervate-related materials with sophisticated properties and emerging applications. In this review, the most recent progress in the design strategies of macromolecular complex coacervation is discussed with respect to different key parameters, including macromolecular structure, mixing ratio, ionic strength, pH, and temperature, etc. Furthermore, the applications of these multiple-functional coacervate materials, oriented toward advanced encapsulation, are further summarized into several active domains in wastewater treatment, protein purification, food formulation, underwater adhesives, drug delivery, and cellular mimics. Finally, perspectives and future challenges related to the further advancement of macromolecular complex coacervates are proposed.

Enhanced Antiglioblastoma Efficacy of Neovasculature and Glioma Cells Dual Targeted Nanoparticles.

Combining treatment of anticancer cells and antiangiogenesis is considered to be a potential targeted strategy for brain glioblastoma therapy. In this study, by utilizing the overexpression of Interleukin 13 receptor α2 (IL-13Rα2) on the glioma cells and heparan sulfate on neovascular endothelial cells, we developed a paclitaxel (PTX) loaded Pep-1 and CGKRK peptide-modified PEG-PLGA nanoparticle (PC-NP-PTX) for glioma cells and neovasculature dual-targeted chemotherapy to enhance the antiglioma efficacy. There were significant differences both on the enhancement of cellular uptake in HUVEC and C6 cells and on the improvement of in vitro antiglioma activity in the respect of proliferation, tumor spheroid growth, tube formation, and migration between PC-NP-PTX and Taxol and NP-PTX. As for C6 cells, the IC50 were 3.59 ± 0.056, 2.37 ± 0.044, 1.38 ± 0.028, 1.82 ± 0.035, and 1.00 ± 0.016 µg/mL of Taxol, NP-PTX, Pep-NP-PTX, CGKRK-NP-PTX, and PC-NP-PTX, and for HUVEC cells, the IC50 were 0.44 ± 0.006, 0.33 ± 0.005, 0.25 ± 0.005, 0.19 ± 0.004, and 0.16 ± 0.004 µg/mL of Taxol, NP-PTX, Pep-NP-PTX, CGKRK-NP-PTX, and PC-NP-PTX, respectively. In vivo distribution assays confirmed that PC-NP-PTX targeted and accumulated effectively at glioma site. PC-NP-PTX showed a longer median survival time of 61 days when compared with Taxol (22 days), NP-PTX (24 days), Pep-NP-PTX (32 days), and CGKRK-NP-PTX (34 days). The in vivo antiglioma efficacy and safety evaluation showed PC-NP-PTX significantly enhanced the antiglioma efficacy and displayed negligible acute toxicity.

A pre-formulation study of a polymeric solid dispersion of paclitaxel prepared using a quasi-emulsion solvent diffusion method to improve the oral bioavailability in rats.

OBJECTIVE: To preliminarily develop a surfactant-free, polymeric solid dispersion (PSD) of paclitaxel suitable for oral administration. METHODS: A co-solvent quench method was applied to screen the proper polymer matrix of the PSD which were prepared in a liquid system using a quasi-emulsion solvent diffusion method (QESDM). Three dissolution experiments and two in vivo tests in rats were used to explain the differences among the formulations. RESULTS: The theoretical solubility ratio of amorphous/crystalline PTX was 92.6 (37 °C). Hydroxypropyl methylcellulose acetate succinate (HPMCAS) was chosen as the polymer carrier of the PSD and a porous silicon dioxide [called white carbon black (WCB)] was selectable to be used to further adjust the dissolution rate. The absolute oral bioavailability (AOB, 20 mg/kg) of the three formulas [HPMCAS/paclitaxel/WCB = 4/1/0 (F1), 8/1/0 (F2) and 4/1/4 (F3), w/w/w] were 11.8, 13.6 and 25.6%, respectively. The AOB of F3 is nearly seven times higher than that (3.8%) of paclitaxel material (a control). The advantage of higher HPMCAS/paclitaxel ratio of F2 in a dissolution test was not reflected in the first in vivo test due to the relatively higher dose of polymer which could not be effectively dissolved under the limitation of intestinal environment. This was deduced from the dissolution tests and was finally validated when the oral dose of PTX (and thus polymer) was reduced. The relevant AOBs (10 mg/kg) were 10.4, 20.8 and 19.6%, respectively. CONCLUSION: The PSD is a promising formulation strategy and the QESDM is a practical preparation method to implement such formulation design.

[Preparation of solid dispersion of triterpenoid acids from Eriobotrya japonica leaf and study on their dissolution in vitro].

UNLABELLED: To prepare the solid dispersion of Eriobotrya japonica leaf triterpenoid acids(EJA) in order to enhance their dissolution characteristics in vitro. METHODS: Taking ursolic acid and oleanolic acid in vitro dissolution as an indicator, the influence of factors including different water-soluble carriers (PEG 6000, PVPk30 and P188) and the drug/carrier weight ratio for the preparation of solid dispersion were examined using single factor experiment. Differential scanning calorimetry (DSC) and X-ray diffraction (X-RD) were used to describe the characterization of solid dispersion. RESULTS: P188 was used as appropriate carrier for the preparation of solid dispersion and the drug/carrier weight ratio was 1:5. The X-RD and DSC showed EJA existed in the solid dispersion as the way of amorphous. The dissolution rate of EJA solid dispersion was significantly higher than physical mixture and EJA. CONCLUSION: The solid dispersion prepared with P188 can significantly increase the solubility and dissolution of EJA in vitro. This study provides the scientific evidence for further preparation of solid dispersion tablet.

Methylation of SSTR4 promoter region in multiple mental health disorders.

The existence of a shared genetic basis for mental disorders has long been documented, yet research on whether acquired epigenetic modifications exhibit common alterations across diseases is limited. Previous studies have found that abnormal methylation of cg14631053 at the SSTR4 promoter region mediates the onset of alcohol use disorder. However, whether aberrant methylation of the SSTR4 gene promoter is involved in other mental health disorders remains unclear. In this study, leveraging publicly available data, we identified that changes in methylation of cg14631053 from the SSTR4 promoter region are involved in the development of bipolar disorder and schizophrenia. Furthermore, the direction of methylation changes in the SSTR4 promoter region is disease-specific: hypomethylation is associated with the onset of bipolar disorder and schizophrenia, rather than major depressive disorder. Methylation levels of cg14631053 correlate with chronological age, a correlation that can be disrupted in patients with mental health disorders including schizophrenia and bipolar disorder. In conclusion, SSTR4 promoter methylation may serve as a marker for identifying bipolar disorder and schizophrenia, providing insights into a transdiagnostic mechanism for precision medicine in the future.

Anti-BCMA CAR-T therapy for multiple myeloma with extramedullary disease: A case report and review of the literature.

INTRODUCTION: Multiple myeloma (MM) with extramedullary disease (EMD) is rare in clinical practice, and B cell maturation antigen (BCMA) CAR-T cell therapy is a novel therapy for hematologic malignancies. Very few reports have been published on the effect of CAR-T-cell therapy in MM with EMD. Here, we report a case of MM with extramedullary lesions treated with BCMA CAR-T therapy. CASE PRESENTATION: A 66-year-old female patient presented to our hospital with an enlarged left maxillary gingiva. DIAGNOSIS: Diagnosis of indolent MM stage III (DS staging) and stage III (ISS and R ISS) with extramedullary lesions. INTERVENTION: The patient underwent a clinical trial of humanized anti-BCMA CAR T cell therapy. RESULTS: Symptoms improved; left gingival hyperplasia and swelling resolved; left buccal mass resolved; and neck and submandibular masses resolved. Pathological examination of the exfoliated masses showed necrotic tissue. CONCLUSION: MM with extramedullary lesions often has limited treatment options, and traditional chemotherapy methods are ineffective; however, BCMA CAR-T cell therapy can significantly improve the symptoms of extramedullary lesions in MM.

Exosomal biomarkers in the differential diagnosis of ovarian tumors: the emerging roles of CA125, HE4, and C5a.

OBJECTIVE: Investigating the utility of serum exosomal markers CA125, HE4, and C5a, both individually and in combination, for distinguishing between benign and malignant ovarian tumors. METHODS: In this study, we selected a total of 234 patients diagnosed with ovarian tumors, including 34 with malignant tumors, 10 with borderline ovarian tumors, and 190 with benign tumors. This study conducted comparisons of exosomal levels of CA125, HE4, and C5a among distinct groups, as well as making comparisons between serum and exosomal levels of CA125 and HE4. Furthermore, the diagnostic performance was assessed through Receiver Operating Characteristic (ROC) curve analysis. The Area Under the Curve (AUC) was computed, and a comparative evaluation of sensitivity and specificity was conducted to ascertain their effectiveness in determining the nature of ovarian tumors across different markers. RESULTS: Serum CA125 and HE4 levels, the ROMA index, exosomal CA125, HE4, C5a levels, and their combined applied value (OCS value) were notably elevated in the ovarian non-benign tumor group compared to the benign tumor group, with statistical significance (P < 0.05). Exosomal and serum levels of CA125 and HE4 exhibited a positive correlation, with concentrations of these markers in serum surpassing those in exosomes. The combined OCS (AUC = 0.871) for CA125, HE4, and C5a in exosomes demonstrated superior sensitivity (0.773) and specificity (0.932) compared to serum tumor markers (CA125, HE4) and the ROMA index. The tumor stage represents an autonomous risk factor influencing the prognosis of individuals with ovarian malignancies. CONCLUSION: The stage of ovarian malignancy is an independent risk factor for its prognosis. The combination of exosomal CA125, HE4 and C5a has a higher clinical value for the identification of the nature of ovarian tumours.

PDE3B regulates KRT6B and increases the sensitivity of bladder cancer cells to copper ionophores.

Cuproptosis is a new Cu-dependent programmed cell death manner that has shown regulatory functions in many tumor types, however, its mechanism in bladder cancer remains unclear. Here, we reveal that Phosphodiesterase 3B (PDE3B), a cuproptosis-associated gene, could reduce the invasion and migration of bladder cancer. PDE3B is downregulated in bladder cancer tissues, which is correlated with better prognosis. Conversely, overexpression of PDE3B in bladder cancer cell could significantly resist invasion and migration, which is consistent with the TCGA database results. Future study demonstrate the anti-cancer effect of PDE3B is mediated by Keratin 6B (KRT6B) which leads to the keratinization. Therefore, PDE3B can reduce KRT6B expression and inhibit the invasion and migration of bladder cancer. Meanwhile, increased expression of PDE3B was able to enhance the sensitivity of Cuproptosis drug thiram. This study show that PDE3B/KRT6B is a potential cancer therapeutic target and PDE3B activation is able to increase the sensitivity of bladder cancer cells to copper ionophores.

Using Er/Cd-Codoped Bi4O5Br2 Microspheres to Enhance Antibiotic Degradation under Visible Illumination: A Combined Experimental and DFT Investigation.

High levels of antibiotic accumulation and the difficulty of degradation can have serious consequences for the environment and, therefore, require urgent attention. To solve this problem, a synergistic Er and Cd ion-codoped Bi4O5Br2 photocatalyst was proposed. The degradation rate of sulfamethoxazole (SMX) by Er/Cd-Bi4O5Br2 was eight times higher than that of pure Bi4O5Br2, exceeding that of single Er-doped or Cd-doped Bi4O5Br2, which was attributed to the ability of Er/Cd-Bi4O5Br2 to generate a variety of free radicals. Experimental results and theoretical calculations suggested a possible mechanism for the improved photocatalytic degradation rate. The reduction of the band gap can facilitate the production of electron-hole pairs, which play a significant role in the production of reactive radicals. Furthermore, an optimal stabilized structure of the ErCd-Bi4O5Br2 dopant system was identified based on the formation energy formulas of different ligand configurations. These findings offer promising potential for the degradation of broad-spectrum antibiotics and provide valuable insights for the design and modification of photocatalytic materials.

Single-atom Pt-CeO2/Co3O4 catalyst with ultra-low Pt loading and high performance for toluene removal.

The design and manufacture of high activity and thermal stability catalysts with minimal precious metal loading is essential for deep degradation of volatile organic compounds (VOCs). In this paper, a novel single-atom Pt-CeO2/Co3O4 catalyst with ultra-low Pt loading capacity (0.06 wt%, denoted as 0.06Pt-SA) was fabricated via one-step co-precipitation method. The 0.06Pt-SA exhibited excellent toluene degradation activity of T90 = 169 °C, matched with the nanoparticle Pt-supported CeO2/Co3O4 catalyst with more than six times higher Pt loading (0.41 wt%, denoted as 0.41Pt-NP). Moreover, the ultra-long durability (toluene conversion remains 99% after 120 h stability test) and excellent toluene degradation ability in a wide space speed range of 0.06Pt-SA were superior to that of 0.41Pt-NP catalyst. The excellent performance was derived from the strong metal-support interaction (SMSI) between the single atomic Pt and the carrier, which induced more Pt0 and Ce3+ for oxygen activation and more Co3+ for toluene removal. The in situdiffuse reflectance infrared spectroscopy (DRIFTS) experiments confirmed that the conversion of intermediates was accelerated in the reaction process, thereby promoting the toluene degradation. Our results should inspire the exploitation of noble single-atomic modification strategy for developing the low cost and high performance VOCs catalyst.

Visual/Photoelectrochemical Off-On Sensor Based on Cu/Mn Double-Doped CeO2 and Branched Sheet Embedded Cu2O/CuO Nanocubes.

An integrated dual-signal bioassay was devised to fulfil thrombin (TB) ultrasensitive detection by integrating visualization with the photoelectrochemical technique based on G-quadruplex/hemin. During the process, branched sheet embedded copper-based oxides prepared with illumination and alkaline condition play a vital role in obtaining the desirable photocurrent. The switchover of photoelectrochemical signal was realized by the adjustable distance between electron acceptor G-quadruplex/hemin and interface materials due to dissociation of the Cu/Mn double-doped cerium dioxide (CuMn@CeO2)/DNA caused by the addition of TB. Then, CuMn@CeO2 transferred onto visual zones triggered catalytic reactions under the existence of 3,3',5,5'-tetramethylbenzidine and hydrogen peroxide, making a variation in color recognized by the naked eye and providing visual prediction. Under optimized conditions, this bioassay protocol demonstrated wide linear ranges (0.0001-50 nM), high selectivity, stability, and reproducibility. More importantly, the proposed visual/photoelectrochemical transduction mechanism platform exhibits a lower background signal and more reliable detection results, which also offers an effective way for detecting other proteins and nucleic acids.

Light-Writing and Projecting Multicolor Fluorescent Hydrogels for On-Demand Information Display.

Intelligent rewritable display systems have been long expected to reduce the heavy consumption of single-use or transient devices in the age of Internet-of-Things. However, it remains challenging to construct such systems with integrated functionality of remote control, rapid activation, multicolor and multimode display. Herein, by learning from the unique multilayer arrangement of chromatophores in chameleon skins, a promising kind of rewritable hydrogel multicolor systems is presented that can combine the merits of near-infrared (NIR) light-writing and projecting modes for on-demand information display. Specifically, the systems have typical multilayer layout consisting of poly(dimethylsiloxane) (PDMS)-sealed carbon nanotubes (CNTs) film as photothermal control unit and embedded fluorescent hydrogels as multicolor display unit, in which thermoresponsive hydrogel is constrained within non-responsive hydrogel. Such rational structure design results in the establishment of one promising display mechanism via the cascading "light trigger-heat generation-fluorescence output" process. On this basis, rapid and reversible hand-written display of arbitrary information is achieved within 5 s. Also, sustainable light-projecting display of predesigned multicolor patterns is demonstrated due to the multilayer design that ensures easy patterning of photothermal control or hydrogel display layer. This study brings functional-integrated merits for novel rewritable display systems and open new possibility to construct high-end products for information display/transmission.