Búsqueda | OPS/OMS Uruguay

1.

Tumor-Derived Retinoic Acid Regulates Intratumoral Monocyte Differentiation to Promote Immune Suppression.

Devalaraja, Samir; To, Tsun Ki Jerrick; Folkert, Ian W; Natesan, Ramakrishnan; Alam, Md Zahidul; Li, Minghong; Tada, Yuma; Budagyan, Konstantin; Dang, Mai T; Zhai, Li; Lobel, Graham P; Ciotti, Gabrielle E; Eisinger-Mathason, T S Karin; Asangani, Irfan A; Weber, Kristy; Simon, M Celeste; Haldar, Malay.

Cell ; 180(6): 1098-1114.e16, 2020 03 19.

Artículo en Inglés | MEDLINE | ID: mdl-32169218

2.

BACH1 Orchestrates Lung Cancer Metastasis.

Anderson, Nicole M; Simon, M Celeste.

Cell ; 178(2): 265-267, 2019 07 11.

Artículo en Inglés | MEDLINE | ID: mdl-31257029

3.

Cellular adaptation to hypoxia through hypoxia inducible factors and beyond.

Lee, Pearl; Chandel, Navdeep S; Simon, M Celeste.

Nat Rev Mol Cell Biol ; 21(5): 268-283, 2020 05.

Artículo en Inglés | MEDLINE | ID: mdl-32144406

4.

SnapShot: Hypoxia-Inducible Factors.

Lee, Kyoung Eun; Simon, M Celeste.

Cell ; 163(5): 1288-1288.e1, 2015 Nov 19.

Artículo en Inglés | MEDLINE | ID: mdl-26590427

5.

BACH1 Orchestrates Lung Cancer Metastasis.

Anderson, Nicole M; Simon, M Celeste.

Cell ; 179(3): 800, 2019 Oct 17.

Artículo en Inglés | MEDLINE | ID: mdl-31626776

6.

Moonlighting functions of metabolic enzymes and metabolites in cancer.

Pan, Chaoyun; Li, Bo; Simon, M Celeste.

Mol Cell ; 81(18): 3760-3774, 2021 09 16.

Artículo en Inglés | MEDLINE | ID: mdl-34547237

7.

Activation of Î³-globin expression by hypoxia-inducible factor 1α.

Feng, Ruopeng; Mayuranathan, Thiyagaraj; Huang, Peng; Doerfler, Phillip A; Li, Yichao; Yao, Yu; Zhang, Jingjing; Palmer, Lance E; Mayberry, Kalin; Christakopoulos, Georgios E; Xu, Peng; Li, Chunliang; Cheng, Yong; Blobel, Gerd A; Simon, M Celeste; Weiss, Mitchell J.

Nature ; 610(7933): 783-790, 2022 10.

Artículo en Inglés | MEDLINE | ID: mdl-36224385

8.

HIF: a master regulator of nutrient availability and metabolic cross-talk in the tumor microenvironment.

Missiaen, Rindert; Lesner, Nicholas P; Simon, M Celeste.

EMBO J ; 42(6): e112067, 2023 03 15.

Artículo en Inglés | MEDLINE | ID: mdl-36808622

9.

Even Cancer Cells Watch Their Cholesterol!

Riscal, Romain; Skuli, Nicolas; Simon, M Celeste.

Mol Cell ; 76(2): 220-231, 2019 10 17.

Artículo en Inglés | MEDLINE | ID: mdl-31586545

10.

Epidermal sensing of oxygen is essential for systemic hypoxic response.

Boutin, Adam T; Weidemann, Alexander; Fu, Zhenxing; Mesropian, Lernik; Gradin, Katarina; Jamora, Colin; Wiesener, Michael; Eckardt, Kai-Uwe; Koch, Cameron J; Ellies, Lesley G; Haddad, Gabriel; Haase, Volker H; Simon, M Celeste; Poellinger, Lorenz; Powell, Frank L; Johnson, Randall S.

Cell ; 133(2): 223-34, 2008 Apr 18.

Artículo en Inglés | MEDLINE | ID: mdl-18423195

11.

Hypoxia-Inducible Factor Signaling in Macrophages Promotes Lymphangiogenesis in Leishmania major Infection.

Bowlin, Anne; Roys, Hayden; Wanjala, Humphrey; Bettadapura, Manjunath; Venugopal, Gopinath; Surma, Jessica; Simon, M Celeste; Weinkopff, Tiffany.

Infect Immun ; 89(8): e0012421, 2021 07 15.

Artículo en Inglés | MEDLINE | ID: mdl-34031127

12.

Dysregulated mTORC1 renders cells critically dependent on desaturated lipids for survival under tumor-like stress.

Young, Regina M; Ackerman, Daniel; Quinn, Zachary L; Mancuso, Anthony; Gruber, Michaela; Liu, Liping; Giannoukos, Dionysios N; Bobrovnikova-Marjon, Ekaterina; Diehl, J Alan; Keith, Brian; Simon, M Celeste.

Genes Dev ; 27(10): 1115-31, 2013 May 15.

Artículo en Inglés | MEDLINE | ID: mdl-23699409

13.

Endothelial Hypoxia-Inducible Factor-2α Is Required for the Maintenance of Airway Microvasculature.

Jiang, Xinguo; Tian, Wen; Tu, Allen B; Pasupneti, Shravani; Shuffle, Eric; Dahms, Petra; Zhang, Patrick; Cai, Haoliang; Dinh, Thanh T; Liu, Bo; Cain, Corey; Giaccia, Amato J; Butcher, Eugene C; Simon, M Celeste; Semenza, Gregg L; Nicolls, Mark R.

Circulation ; 139(4): 502-517, 2019 01 22.

Artículo en Inglés | MEDLINE | ID: mdl-30586708

14.

The role of oxygen availability in embryonic development and stem cell function.

Simon, M Celeste; Keith, Brian.

Nat Rev Mol Cell Biol ; 9(4): 285-96, 2008 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-18285802

15.

Fructose-1,6-bisphosphatase opposes renal carcinoma progression.

Li, Bo; Qiu, Bo; Lee, David S M; Walton, Zandra E; Ochocki, Joshua D; Mathew, Lijoy K; Mancuso, Anthony; Gade, Terence P F; Keith, Brian; Nissim, Itzhak; Simon, M Celeste.

Nature ; 513(7517): 251-5, 2014 Sep 11.

Artículo en Inglés | MEDLINE | ID: mdl-25043030

16.

Intratumoral oxygen gradients mediate sarcoma cell invasion.

Lewis, Daniel M; Park, Kyung Min; Tang, Vitor; Xu, Yu; Pak, Koreana; Eisinger-Mathason, T S Karin; Simon, M Celeste; Gerecht, Sharon.

Proc Natl Acad Sci U S A ; 113(33): 9292-7, 2016 08 16.

Artículo en Inglés | MEDLINE | ID: mdl-27486245

17.

Oxygen availability and metabolic reprogramming in cancer.

Xie, Hong; Simon, M Celeste.

J Biol Chem ; 292(41): 16825-16832, 2017 10 13.

Artículo en Inglés | MEDLINE | ID: mdl-28842498

18.

HIF modulation of Wnt signaling regulates skeletal myogenesis in vivo.

Majmundar, Amar J; Lee, David S M; Skuli, Nicolas; Mesquita, Rickson C; Kim, Meeri N; Yodh, Arjun G; Nguyen-McCarty, Michelle; Li, Bo; Simon, M Celeste.

Development ; 142(14): 2405-12, 2015 Jul 15.

Artículo en Inglés | MEDLINE | ID: mdl-26153230

19.

Hypoxia-inducible factors and the response to hypoxic stress.

Majmundar, Amar J; Wong, Waihay J; Simon, M Celeste.

Mol Cell ; 40(2): 294-309, 2010 Oct 22.

Artículo en Inglés | MEDLINE | ID: mdl-20965423

20.

Deregulation of the Hippo pathway in soft-tissue sarcoma promotes FOXM1 expression and tumorigenesis.

Eisinger-Mathason, T S Karin; Mucaj, Vera; Biju, Kevin M; Nakazawa, Michael S; Gohil, Mercy; Cash, Timothy P; Yoon, Sam S; Skuli, Nicolas; Park, Kyung Min; Gerecht, Sharon; Simon, M Celeste.

Proc Natl Acad Sci U S A ; 112(26): E3402-11, 2015 Jun 30.

Artículo en Inglés | MEDLINE | ID: mdl-26080399

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Tumor-Derived Retinoic Acid Regulates Intratumoral Monocyte Differentiation to Promote Immune Suppression.

BACH1 Orchestrates Lung Cancer Metastasis.

Cellular adaptation to hypoxia through hypoxia inducible factors and beyond.

SnapShot: Hypoxia-Inducible Factors.

BACH1 Orchestrates Lung Cancer Metastasis.

Moonlighting functions of metabolic enzymes and metabolites in cancer.

Activation of Î³-globin expression by hypoxia-inducible factor 1α.

HIF: a master regulator of nutrient availability and metabolic cross-talk in the tumor microenvironment.

Even Cancer Cells Watch Their Cholesterol!

Epidermal sensing of oxygen is essential for systemic hypoxic response.

Hypoxia-Inducible Factor Signaling in Macrophages Promotes Lymphangiogenesis in Leishmania major Infection.

Dysregulated mTORC1 renders cells critically dependent on desaturated lipids for survival under tumor-like stress.

Endothelial Hypoxia-Inducible Factor-2α Is Required for the Maintenance of Airway Microvasculature.

The role of oxygen availability in embryonic development and stem cell function.

Fructose-1,6-bisphosphatase opposes renal carcinoma progression.

Intratumoral oxygen gradients mediate sarcoma cell invasion.

Oxygen availability and metabolic reprogramming in cancer.

HIF modulation of Wnt signaling regulates skeletal myogenesis in vivo.

Hypoxia-inducible factors and the response to hypoxic stress.

Deregulation of the Hippo pathway in soft-tissue sarcoma promotes FOXM1 expression and tumorigenesis.