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Clin Appl Thromb Hemost ; 29: 10760296231152898, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37069796

RESUMEN

Deep vein thrombosis (DVT) and the associated possible complication of pulmonary artery embolism (LAE) represent a recognized reason for significant perioperative morbidity and mortality. There is a risk of pulmonary artery embolism through embolization. The aim of the study was to investigate the influence of various risk factors on the clinical outcome of the therapy, particularly regarding whether maintenance therapy offers a benefit in terms of the frequency of bleeding and thrombotic events. 80 patients were included, some of them retrospectively from July 2018. The observational period was set to 12 months after the DVT event. In the present sample with n = 80, with 57.5% men and 42.5% women (after 12 months of observation: n = 78), a success rate of the therapies administered of 89.7% was recorded. Only 8.9% showed partial recanalization. 3.8% of the patients had a relapse (also beyond the localization of the leg and pelvic veins) and 8.8% had a residual thrombus during the first 12 months of observation. In this study, BARC (Bleeding Academic Research Consortium) and HAS-BLED (Hypertension, Abnormal renal and liver function, Stroke, Bleeding, Labile INR, Elderly, Drugs or alcohol) scores for identifying the risk of bleeding and Wells scores for assessing the risk of having a thrombosis were used. The Villalta score tested in this study showed significant correlations with residual thrombus (P < .001), recurrence within 12 months (P < .001), and the risk of bleeding (P < .001) and is capable to provide an assessment of the variables mentioned not only at the possible end of therapy but also at the start of anticoagulant therapy.


Asunto(s)
Embolia Pulmonar , Accidente Cerebrovascular , Trombofilia , Trombosis de la Vena , Anciano , Femenino , Humanos , Masculino , Anticoagulantes/uso terapéutico , Hemorragia/inducido químicamente , Embolia Pulmonar/tratamiento farmacológico , Estudios Retrospectivos , Factores de Riesgo , Accidente Cerebrovascular/tratamiento farmacológico , Trombofilia/tratamiento farmacológico , Trombosis de la Vena/tratamiento farmacológico , Estudios Prospectivos
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