Hydraulic optimalization of surgical flow drainage in physical model.

In the present study, the flow in deep, closed wound with various types and position of drain was studied. A physical model of regular geometrical wound was designed to investigate the events occurring in the wound from the standpoint of hydraulics. Results of the study showed that the commonly used method of drain application could be improved. The results may also prove helpful for improvement of the existing drains and their more favorable positioning.

Histopathologic features of T-cell mediated colonic injury induced with 2,4-dinitrofluorobenzene in BALB/c mice.

The aim of the study was to reveal the histopathologic features of intestinal inflammation as demonstrated in BALB/c mice, using the challenge of 2,4-dinitrofluorobenzene (DNFB) with or without previous sensitization. Forty mice were randomized into 5 groups. Two groups of animals were treated with rectal enema of 0.2% or 1.0% of 2,4-dinitrofluorobenzene solution. Third group was pretreated with 2 sensitizing doses of DNFB. Two control groups were treated with PBS or acetone and vehicle enema only (acetone and olive oil). In order to assess the extent of colonic inflammation and damage, a histopathologic score scale was developed. In contrast to scanty superficial ulcerations and mild edema observed in the control group of animals, edema, ulcerations, hemorrhage, necrosis and infiltration of inflammatory cells were observed in experiment groups treated with enema of DNFB. Total score of lesion as well almost all inflammatory parameters of injury observed were highest in previously sensitized animals. The results of this study clearly demonstrated the pattern of colonic inflammation induced with DNFB using the histopathologic scoring scale system.

[The Budd-Chiari syndrome--case report of a patient with hepatic vein occlusion and adenocarcinoma of the lung]. / Budd-Chiarijev sindrom--prikaz bolesnika s okluzijom hepatalnih vena i adenokarcinomom pluca.

The case of a patient with sudden onset of abdominal pain, hepatomegaly and laboratory findings which indicated necrosis of a parenchymal organ is reported. Patient died soon after the admission to hospital after fulminant disease development. At the time of admission diagnosis of hepatic vein occlusion, i.e., Budd-Chiari syndrome was made based on ultrasonographic finding. Obduction confirmed this finding showing lung adenocarcinoma with liver metastases as well as occlusion of all hepatic vein branches with thrombi. This report emphasizes the role of ultrasonographic diagnostics in the early diagnosis of Budd-Chiari syndrome.

[Reconstruction of the cervical esophagus with free autotransplantation of the jejunum--direct monitoring of viability]. / Rekonstrukcija vratnog jednjaka slobodnim autotransplantatom jejunuma--izravno pracenje vitalnosti.

Although free jejunum transfer has become an accepted form of hypopharyngeal reconstruction, an ideal method of monitoring the viability of the graft has not been devised yet. The method of direct visualisation through the incision in the skin above the transferred jejunum has proven very reliable and easy to perform, especially for the nursing staff. This reliable method of monitoring free vascularised jejunum to the neck region has been used in two patients. After two days of direct monitoring, the incision in the skin healed without additional sutures. No failures of the graft occurred, and 12 days later the patients were able to swallow fluids without difficulty. The effectiveness of this technique has surpassed that of all previously published methods.

[Current approaches in surgical treatment of ulcerative colitis (reports of our results)]. / Suvremeni pristupi kirurskom lijecenju ulceroznog kolitisa (prikaz vlastitih rezultata).

The results of surgical treatment of ulcerative colitis in 19 patients in the period from 1989 to 1997 are presented. Of surgical techniques, in 17 patients a pouch was formed, namely, in six patients W pouch, in four patients S pouch, and in seven patients J pouch, while in two patients the pouch was not formed due to the incontinence of anal sphincter. In these patients the stool derivation was achieved by permanent terminal ileostomy. Fifteen patients were operated in elective program, while in four patients emergency surgery was indicated. In emergency surgery the first step was subtotal colectomy, with ileostomy and sigmoidostomy. In further treatment we introduced corticosteroid clyster in the opening of sigmoidostoma, with good results. The quality of life of persons with the pouch is higher compared to patients with permanent ileostomy. In patients who require surgical treatment of ulcerative colitis, the operation of forming an ileal pouch and anal anastomosis should be done.

[Mathematical model of hydrodynamic flow in irrigation-suction drainage]. / Mathematisches Modell von Strömungsverhältnissen bei Spül-Saug-Drainagen.

The aim of this study was to evaluate the flow of fluid between closed drains in deep wounds and osteomyelitic and abscess cavities. For the purposes of this study we created a numerical wound model. This model had a symmetric geometrical shape and we simulated flow of fluid between the drains in four variants of distance between these drains. The results of this model showed that the distance often used between drains in clinical practice is not effective. Better drainage could be achieved by spacing the drains more. These results can be used for more functional and better drainage if drains are placed properly in osteomyelitic or wound cavities.

[Osteosynthesis revision in war fractures]. / Osteosynthesenwechsel bei Kriegsfrakturen.

The results of early conversion of war fractures by the application of AO osteosynthesis in A group (n = 32) of the injured, were compared with B group (n = 187) of injured, treated definitely with external fixator. There were statistical evaluations and X-ray observations of healing in both groups, as well as the appearances of the most frequent complications such as: Pintract infection, osteitis, pseudoarthrosis and reoperation. Statistically less significant appearance of complications in A group during 2nd and 6th month (p < 0.001) was observed. In 12th month of observation, these differences statistically disappeared. Healing observed by X-ray in 2nd, 6th and 12th month of observation were no statistically significant differences between the two observed groups.