1.
Org Lett
; 9(1): 45-8, 2007 Jan 04.
Artículo
en Inglés
| MEDLINE
| ID: mdl-17192081
RESUMEN
[reaction: see text] A key structural feature of the Neocarzinostatin chromophore is a reactive epoxydiyne. We present here a new method for the preparation of epoxydiynes by the addition of an allenyl zinc bromide to a propargylic ketone.