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1.
Environ Sci Technol ; 51(12): 7286-7294, 2017 Jun 20.
Artículo en Inglés | MEDLINE | ID: mdl-28548824

RESUMEN

Divergence in recent oil and gas related methane emission estimates between aircraft studies (basin total for a midday window) and emissions inventories (annualized regional and national statistics) indicate the need for better understanding the experimental design, including temporal and spatial alignment and interpretation of results. Our aircraft-based methane emission estimates in a major U.S. shale gas basin resolved from west to east show (i) similar spatial distributions for 2 days, (ii) strong spatial correlations with reported NG production (R2 = 0.75) and active gas well pad count (R2 = 0.81), and (iii) 2× higher emissions in the western half (normalized by gas production) despite relatively homogeneous dry gas and well characteristics. Operator reported hourly activity data show that midday episodic emissions from manual liquid unloadings (a routine operation in this basin and elsewhere) could explain ∼1/3 of the total emissions detected midday by the aircraft and ∼2/3 of the west-east difference in emissions. The 22% emission difference between both days further emphasizes that episodic sources can substantially impact midday methane emissions and that aircraft may detect daily peak emissions rather than daily averages that are generally employed in emissions inventories. While the aircraft approach is valid, quantitative, and independent, our study sheds new light on the interpretation of previous basin scale aircraft studies, and provides an improved mechanistic understanding of oil and gas related methane emissions.


Asunto(s)
Contaminantes Atmosféricos/análisis , Metano/análisis , Aeronaves , Gas Natural , Proyectos de Investigación
2.
J Am Coll Cardiol ; 41(1): 73-80, 2003 Jan 01.
Artículo en Inglés | MEDLINE | ID: mdl-12570948

RESUMEN

OBJECTIVES: This study evaluated the long-term reliability of an implantable cardioverter defibrillator (ICD) lead to determine the incidence, clinical presentation, and management of lead failure. BACKGROUND: Despite recent advances in ICD technology, the long-term reliability of ICD leads remains a significant problem. METHODS: Concern about long-term reliability of coaxial polyurethane ICD leads caused us to systematically study all patients implanted with Medtronic (Minneapolis, Minnesota) 6936 lead at our institution. We performed follow-up of 74 patients with 76 ICD leads that were implanted from February 28, 1995 to September 8, 1997. Thirty-seven patients underwent routine clinical ICD follow-up testing and ventricular fibrillation induction to determine the status of their ICD lead after a mean follow-up of 68.6 +/- 8.2 months. RESULTS: The lead survival analysis shows a cumulative failure probability of 37% (confidence interval, 24% to 54%) at 68.6 months. Six patients demonstrated a previously undescribed mode of ICD lead failure: prolonged oversensing immediately after shock therapy. The use of short interval counters to monitor nonphysiologic R-R intervals and the measurement of ring-to-coil impedance detected early lead failures in five patients. CONCLUSIONS: This analysis shows: 1) problems with ICD leads may not become apparent until late during follow-up and may become a significant late problem, 2) a "signature" mode of lead failure for the 6936 consisting of oversensing of electrical noise following shocks, 3) early detection of lead failure with a short interval counter algorithm or measurement of ring-to-coil impedance may be clinically useful.


Asunto(s)
Desfibriladores Implantables/efectos adversos , Anciano , Técnicas de Diagnóstico Cardiovascular , Electrocardiografía , Técnicas Electrofisiológicas Cardíacas/métodos , Falla de Equipo/estadística & datos numéricos , Femenino , Humanos , Incidencia , Masculino , Persona de Mediana Edad , Poliuretanos/efectos adversos , Valor Predictivo de las Pruebas , Taquicardia Ventricular/terapia , Factores de Tiempo
3.
J Interv Card Electrophysiol ; 7(2): 181-4, 2002 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-12397229

RESUMEN

Implantable cardioverter defibrillators (ICDs) are now an accepted and effective therapy for treatment of survivors of sudden cardiac death (SCD) and prevention of SCD in high-risk patients. Normal ICD function and delivery of therapy depends on appropriate sensing and detection of myocardial electrical potentials. Electromagnetic interference resulting in ICD malfunction is a well-documented phenomenon, however, there are less well-known external sources of interference, which may cause life threatening ICD malfunction. We report a unique case of repeated inappropriate ICD shocks in a ten-year old boy caused by the ICD sensing alternating current from an unexpected external source.


Asunto(s)
Desfibriladores Implantables/efectos adversos , Disfunción Ventricular Izquierda/terapia , Niño , Electricidad , Diseño de Equipo , Falla de Equipo , Humanos , Masculino , Disfunción Ventricular Izquierda/congénito
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