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1.
Bioinformation ; 20(3): 297-300, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38712006

RESUMEN

The effect of different cavity liners on the shear bond strength of nanocomposite to dentin is of interest. A total of sixty extracted caries-free maxillary, mandibular molars were randomly assigned to four groups in the following manner Group 1: control (no cavity liner), group 2: Biodentin, group 3: Apacal ART and Group 4: Giomer. Following the application of different cavity liners based on the groups, restoration was carried out using nanocomposite resin using the total-etch Tetric N bond adhesive. The samples were thereafter subjected to a shear bond strength test at a cross-head speed of 1 mm/min until bond failure occurred, utilizing the universal testing machine. The one-way ANOVA test and the post hoc test were used to evaluate the data for pairwise group comparisons. Compared to the control group, all groups showed lower shear bond strength to dentin, irrespective of the type of liner. Apacal ART showed higher shear bond strength followed by giomer and biodentin. However, there's no apparent statistical difference between the groups.

2.
J Pharm Bioallied Sci ; 16(Suppl 2): S1690-S1694, 2024 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-38882763

RESUMEN

Background: To assess and contrast the depth of penetration of conventional calcium hydroxide, nanoparticle calcium hydroxide, silver nanoparticles, and combination of nanoparticle calcium hydroxide and silver nanoparticles into dentinal tubules using confocal laser scanning microscope. Materials and Methods: Eighty human single-rooted teeth were decoronated and instrumented up to Protaper Universal F3. Teeth were separated into four groups at random (n = 20) following chemomechanical preparation. Group 1: Control Conventional Calcium Hydroxide; Group 2: Nanoparticle Calcium Hydroxide; group 3: Silver Nanoparticles; group 4: Combination of Nanoparticle Calcium Hydroxide and Silver Nanoparticles. With the use of lentulo spirals, medications were injected into the canals, stirred up with ultrasound, and then kept at 37°C for 24 hours. A 1 mm thick slice was obtained at 5 mm from the root apex by sectioning the root perpendicular to the long axis of the tooth and then put on a glass slide to measure the depth of penetration using a confocal laser microscope. Statistical Analysis: To quantify the depth of penetration among the four groups, a one-way ANOVA was used and post hoc-Tukey's test was used to compare between groups. Results: All of the groups were statistically significant, with group 4 showing the greatest depth of penetration, followed by group 2 and group 3. In contrast, all other groups in the intergroup comparison were statistically significant (P value 0.05) aside from the comparison of group 2 to group 3. Conclusion: Silver nanoparticles and nanoparticle calcium hydroxide together demonstrated greater penetration than calcium hydroxide, silver nanoparticles, and nanoparticle calcium hydroxide alone.

3.
J Pharm Bioallied Sci ; 15(Suppl 1): S582-S587, 2023 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-37654348

RESUMEN

Background and Aims: For endodontic therapy to be successful, the smear layer produced by the root canal instruments must be removed. The study's objective is to evaluate the effectiveness of radicular dentin microhardness modification and smear layer removal utilizing various chelating agents. Materials and Methods: Extracted human mandibular single-rooted premolar teeth were selected for the study. The specimens were sectioned to obtain a standard root length and, working length determination was done. Cleaning and shaping were done in all the samples till the size F3 (Protaper universal). Based on the chelating agents using samples were randomly divided into four groups, Group-I: Saline (negative control), Group-II: 17% EDTA (DeSmear, Ahmedabad, Gujarat) (positive control), Group-III: 0.2% Chitosan (Everest-Biotech, Bengaluru), Group-IV: 20% N-Acetyl cysteine (NAC) (Sisco Research Laboratories, Mumbai), Group-V: 5% Pentetic acid (New Alliance Fine chem Pvt Ltd, Mumbai). All the samples were prepared for smear layer removal and surface roughness evaluation using an atomic force microscope. Results: It was observed that significantly (P = 0.000) the mean roughness average was higher among group II EDTA (148 ± 8.5) followed by group III 0.2% Chitosan (92.5 ± 3.42), group IV 20% NAC (85.2 ± 2.17), and group V 5% Pentetic acid (73.3 ± 3.39) and least by group I Saline (59.3 ± 3.31). The highest smear layer removal was seen with group II (EDTA) followed by group III (0.2% Chitosan), group IV (20% NAC), and group V (Pentetic acid). Conclusion: All the chelating agents removed smear layer in coronal third, middle third whereas none of them were able to entirely eliminate from the apical third. Chitosan with smear layer removal capacity equal to EDTA with limited roughness can be considered as a valid alternative as final irrigant.

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