Youth Perceived Social Support and Symptom Distress: A Random-Intercept Cross-Lagged Panel Model.

Although social support and mental health associations have been extensively investigated, their reciprocal relations in vulnerable youth remain understudied. This study investigated the relations between perceived social support and symptom distress over time whilst differentiating between support from caregivers and significant others. The sample included 257 youth (79% self-identified women, Mage = 19.2, SD = 2.5) who were receiving mental health treatment. Using a Random-Intercept Cross-Lagged Panel Model, results revealed no significant concurrent associations, between-person effects, or cross-lagged effects. The autoregressive effects suggested that perceived social support from caregivers was relatively stable over time, while symptom distress and support from a significant other were not. In all, this study challenged the validity of the social causation and social erosion models in the context of perceived social support and symptom distress among vulnerable youth, revealing an absence of significant reciprocal associations. The stable nature of perceived social support from caregivers compared to support from significant others was highlighted. The study design, hypotheses, and target analyses were preregistered under https://osf.io/f4qpg .

Behavioral inhibition, negative parenting, and social withdrawal: Longitudinal associations with loneliness during early, middle, and late adolescence.

Adolescent loneliness can have detrimental effects on physical and mental health, but there is limited understanding of its antecedents in infancy and childhood. A 20-year longitudinal, multi-informant, and multi-methods study (first data collection in 1998) was conducted to examine mechanisms underlying adolescent loneliness (N = 128, 52% boys, Mage_baseline  = 1.23, SD = 0.02, 99% White, recruitment in Dutch urban, healthcare centers). Structural equation modeling showed that high infant behavioral inhibition (BI) was indirectly associated with high loneliness during adolescence via high childhood social withdrawal. This indirect effect was equally strong during early, middle, and late adolescence. Contrary to expectations, infant parenting did not moderate the relation between BI and social withdrawal. The results suggest a developmental cascade with infant BI showing long-lasting indirect effects on adolescent loneliness up to 20 years later via childhood social withdrawal.

A longitudinal study on changes in food parenting practices during COVID-19 and the role of parental well-being.

The COVID-19 pandemic may negatively influence food parenting practices, also among parents of adolescents. Parental well-being (stress and depressive symptoms) may explain these COVID-19 related changes in food parenting practices (snack structure, healthy structure, modeling, autonomy support, and coercive control). However, most previous studies performed before or during the COVID-19 pandemic have been limited by cross-sectional designs. The aim of the current study among parents of adolescent children was twofold. First, we aimed to examine prospective differences in food parenting practices comparing the situation before and during COVID-19. Second, we aimed to examine both cross-sectional and longitudinal associations between parental well-being and the dimensions of food parenting, while additionally examining whether these prospective associations were more pronounced in parents who had experienced more COVID-19 stressful life events. Parents (N = 290; 74.9% female; at baseline: Mage = 46.9; SDage = 4.3) of adolescent children (at baseline: Mage = 14.3; SDage = 0.6) completed online surveys about parental well-being and food parenting twice: One year before the COVID-19 pandemic (spring 2019) and during the COVID-19 pandemic, 1.5 years after the first measurement (autumn 2020). In general, we found consistent evidence for an average decrease in food autonomy support and an increase in coercive control during COVID-19. However, parental well-being did not seem to explain (changes in) food parenting practices during COVID-19, also not in combination with stressful life events. Our findings suggest that, regardless of parental well-being, the general COVID-19 situation had some small negative influences on autonomy support and coercive control among parents of adolescents. These findings might be explained by parents being more often confronted with unhealthy eating occasions in the COVID-19 home context, triggering these negative parental responses.

Examining food intake similarities in adolescent best friend dyads using longitudinal Actor-Partner Interdependence Models.

Little is known about how adolescent best friends may affect each other's food intake. This study explored whether friendship selection and socialization mechanisms explained potential food intake similarities in adolescent reciprocated best friend dyads. We also tested whether socialization processes were moderated by dyad member's relative zBMI. Members of 145 same-gender best friendship dyads (56% female; Mage = 12.79; SDage = 0.61) reported on their intake of food obtained from home and from outside the home at the beginning and the end of the school year through food frequency questionnaires. Longitudinal Actor-Partner Interdependence Models results showed no indication of selection or socialization, and very limited evidence for the moderation of socialization processes by relative zBMI. These findings indicate that focusing on adolescent reciprocated best friends in dietary interventions may not be valuable.

A SNP, Gene, and Polygenic Risk Score Approach of Oxytocin-Vasopressin Genes in Adolescents' Loneliness.

Not much is known regarding underlying biological pathways to adolescents' loneliness. Insight in underlying molecular mechanisms could inform intervention efforts aimed at reducing loneliness. Using latent growth curve modeling, baseline levels and development of loneliness were studied in two longitudinal adolescent samples. Genes (OXTR, OXT, AVPR1A, AVPR1B) were examined using SNP-based, gene-based, and polygenic risk score (PRS) approaches. In both samples, SNP- and gene-based tests showed involvement of the OXTR gene in development of loneliness, though, significance levels did not survive correction for multiple testing. The PRS approach provided no evidence for relations with loneliness. We recommend alternative phenotyping methods, including environmental factors, to consider epigenetic studies, and to examine possible endophenotypes in relation to adolescents' loneliness.

Oxytocin Receptor Gene (OXTR) and Deviant Peer Affiliation: A Gene-Environment Interaction in Adolescent Antisocial Behavior.

Although the oxytocin receptor gene (OXTR) is involved in aggression and social affiliation, it has not been examined in gene-environment interaction studies. This longitudinal study examined the effect of genetic variants in OXTR and its gene-environment interaction with perceived deviant peer affiliation in the trajectories of antisocial behavior in 323 adolescents (182 males) from 13 to 18 years. Annual assessments of reactive and proactive aggression, delinquency, and friends' delinquency, as well as DNA at age 17 were collected. Gene-based tests yielded no main effect of OXTR, but revealed a significant gene-environment interaction in proactive aggression and delinquency. Variation in the OXTR might affect the influence of deviant peer affiliation on antisocial behavior, contributing to a better understanding of individual differences in antisocial behavior.

Unmet belongingness needs but not high belongingness needs alone predict adverse well-being: A response surface modeling approach.

OBJECTIVE: Previous work has linked high levels of belongingness needs to low well-being, suggesting that high desire for social connection causes problems. Against that view, we hypothesized that problems stem especially from unmet belongingness needs. To examine this, discrepancies between belongingness needs and relationship satisfaction were measured. METHOD: A total of 1,342 adolescents (Mage = 13.94 years, 48.6% boys) completed questionnaires about belongingness needs, relationship satisfaction, loneliness, depressive symptoms, and self-esteem. A combination of polynomial regression analyses with response surface modeling examined the effects of both fulfilled and unmet belongingness needs on well-being. RESULTS: Fulfilled belongingness needs did not affect adolescents' well-being. However, larger discrepancies between high belongingness needs and low relationship satisfaction were related to higher loneliness, more depressive symptoms, and lower self-esteem. Thus, well-being was most strongly affected among adolescents reporting an unmet need to belong. CONCLUSIONS: We add to the current knowledge by emphasizing that especially belongingness needs that exceed relationship satisfaction, regardless of the actual levels of both, contribute to actual health outcomes. Thus, high need to belong is not detrimental per se, but only in combination with low relationship satisfaction. Implications for clinical practice could be to prevent unmet belongingness needs to ultimately alleviate negative affect and self-esteem.

The longitudinal link between mothers' and adolescents' snacking: The moderating role of television viewing.

A large proportion of adolescents eats too many energy-dense snacks, which is detrimental for their current and future health. To understand how to promote healthy dietary behaviors in adolescents, we need to identify factors that affect their snacking. While previous cross-sectional work has shown mother-child similarities in eating behavior, longitudinal studies are lacking. Hence, the first aim of this study was to examine whether maternal snacking predicted changes in adolescents' snacking over time. A second aim was to examine whether adolescents' television viewing magnified the strength of this longitudinal association. Television viewing may increase the motivation to eat the snacks consumed by mothers later on, for example through food advertisement exposure and mindless eating. To address both aims, 2051 adolescents (Mage baseline = 13.81; 51.5% boys) were asked to report on their snacking and television viewing three times, with intervals of one year. Moreover, a subsample of mothers of adolescents (N = 1080) reported on their snacking at baseline as well. The results indicate that maternal snacking indeed predicts adolescents' snacking over time and that this effect is more pronounced among adolescents who watch a great amount of television. These findings attest to the importance of mothers in forming adolescents' snacking, not only concurrently but also prospectively. Additionally, this study highlights the relevance of assessing other home environmental factors that may influence maternal effects on their children's snacking.

Trait and State Levels of Loneliness in Early and Late Adolescents: Examining the Differential Reactivity Hypothesis.

According to the differential reactivity hypothesis, lonely individuals respond differently to their environment compared to nonlonely individuals, which may sustain their loneliness levels. However, this interesting hypothesis has not yet been explored in daily life: Do lonely individuals feel lonely all the time, or do they feel more or less lonely in specific social contexts? The main aim of the present study was to test the differential reactivity hypothesis in daily life by examining in three samples whether trait levels of loneliness affected the levels of state loneliness in different social contexts. We used baseline questionnaires to measure trait loneliness and the Experience Sampling Method to collect data on state loneliness, in early adolescents (N = 269, Mage = 14.49, 59% female) and late adolescents (N = 223, Mage = 19.60, 91% female) from the Netherlands and late adolescents from the United States (N = 126, Mage = 19.20, 51% female). Results provided evidence for the differential reactivity hypothesis in the total sample, as high lonely adolescents experienced higher levels of state loneliness in situations in which they were alone than low lonely adolescents, but also benefited more from being with intimate company than low lonely adolescents. In sum, the present study provided evidence for the differential reactivity hypothesis and showed that the experience of loneliness in daily life was remarkably similar across age and culture. Our findings provide important insights into the daily experiences of trait lonely people, which may provide starting points for interventions.

Loneliness in Early Adolescence: Friendship Quantity, Friendship Quality, and Dyadic Processes.

Friendship quantity and quality are related to adolescent loneliness, but the exact link between these constructs is not well understood. The present study aimed to examine whether adolescents' perception of friendship quantity and quality, and the perceptions of their peers, were related to loneliness. We examined the relation between loneliness and the number of unilateral and reciprocal friendships and compared the views of best friendship quality. Overall, 1,172 Dutch adolescents (49.1% male, M age = 12.81, SD = .43) nominated their friends and rated their friendship quality. Friendship quantity was measured using sociometrics to distinguish reciprocated and unilateral (i.e., one-sided) friendships. The analyses indicated that loneliness was related to fewer reciprocal and unilateral-received friendships (i.e., the adolescent received a friendship nomination but did not reciprocate that nomination) and a lower quality of best friendship. Actor-partner interdependence analyses revealed that adolescents' loneliness was related to a less positive evaluation of their friendship, as reported by adolescents themselves (i.e., a significant actor effect) but not by their friends (i.e., nonsignificant partner effect). These findings (a) indicate that loneliness is negatively related to the number of friends adolescents have, as perceived by themselves and their peers and (b) suggest that, once a friendship is established, lonely adolescents may interpret the friendship quality less positively compared to their friends. Implications of these findings for our current understanding of adolescent loneliness are discussed, and suggestions for future research are outlined.

Adolescents' Loneliness and Depression Associated with Friendship Experiences and Well-Being: A Person-Centered Approach.

Loneliness and depressive symptoms are distinct, but partly overlapping constructs. The current study examined whether clusters of loneliness and depressive symptoms could be identified through latent profile analysis in two samples of 417 and 1140 adolescents (48.40 and 48.68 % male, respectively), on average 12.47 and 12.81 years old, respectively. Four clusters were identified, (1) low on loneliness and depressive symptoms, (2) low on loneliness and high on depressive symptoms, (3) high on loneliness and low on depressive symptoms, and (4) high on loneliness and depressive symptoms. We found that these four clusters were differentially related to friendship quantity and quality as well as to happiness and self-esteem. The current study stresses the importance of assessing both loneliness and depressive symptoms, as their mutual relation within individuals is differentially related to various aspects of adjustment.

Co-development of early adolescent alcohol use and depressive feelings: The role of the mu-opioid receptor A118G polymorphism.

Alcohol use and depressive feelings are often related among early adolescents. However, the nature and underlying mechanisms of this association are not yet clear. The aim of this study was to investigate the co-development of alcohol use and depressive feelings over time and to examine the effects of the mu-opioid receptor (OPRM1) A118G genotype on such co-development. Data from a five-wave longitudinal, genetically informed survey study, with intervals of 4 months among a group of 739 normative early adolescents (12-13 years of age at baseline), were analyzed using a dual latent growth curve approach. OPRM1 status was evaluated from saliva-derived DNA samples. The results indicated a positive association between alcohol use and depressive feelings both at the initial levels and over time, indicating co-development in early adolescence. Compared to OPRM1 118G carriers, homozygous 118A carriers showed a greater increase in frequency of alcohol use and higher levels of depressive feelings over time. Evidence for co-development was only found within the group of homozygous 118A carriers, whereas in OPRM1 118G carriers the development of alcohol use and depressive feelings over time were not significantly associated. These results highlight the potential of OPRM1 as a common etiological factor for the development of alcohol use and depressive feelings in early adolescence.

Social stress in early adolescents' daily lives: Associations with affect and loneliness.

Adolescence is characterized by increased social stress due to changes in interpersonal relationships, but little is known about daily experiences of social stress. The aim of the present study was to examine daily life predictors of increases in social stress, how these increases affected adolescents' mood, and whether loneliness moderated these relations. The Experience Sampling Method was used to measure positive and negative affect and increases in social stress in 278 early adolescents from the Netherlands. Results showed that adolescents were most likely to experience increases in social stress when they were with classmates, during week days, and in the morning. Lonely adolescents showed higher increases in social stress and responded more negatively to increases in social stress, compared to non-lonely adolescents.

A theory-informed emotion regulation variability index: Bray-Curtis dissimilarity.

Emotion regulation (ER) variability refers to how individuals vary their use of ER strategies across time. It helps individuals to meet contextual needs, underscoring its importance in well-being. The theoretical foundation of ER variability recognizes two constituent processes: strategy switching (e.g., moving from distraction to social sharing) and endorsement change (e.g., decreasing the intensity of both distraction and social sharing). ER variability is commonly operationalized as the SD between strategies per observation (between-strategy SD) or within a strategy across time (within-strategy SD). In this article, we show that these SD-based approaches cannot sufficiently capture strategy switching and endorsement change, leading to ER variability indices with poor validity. We propose Bray-Curtis dissimilarity, a measure used in ecology to quantify biodiversity variability, as a theory-informed ER variability index. First, we demonstrate how Bray-Curtis dissimilarity is more sensitive than SD-based approaches in detecting ER variability through two simulation studies. Second, assuming that higher ER variability is adaptive in daily life, we test the relation between ER variability and negative affect in three experience sampling method data sets (total N = [70, 95, 200], number of moment-level observations = [5,040, 6,329, 14,098]). At both the moment level and person level, higher Bray-Curtis dissimilarity predicted lower negative affect more consistently than SD-based indices. We conclude that Bray-Curtis dissimilarity may better capture moment-level within-person ER variability and could have implications for studying variability in other multivariate dynamic processes. The article is accompanied by an R tutorial and practical recommendations for using Bray-Curtis dissimilarity with experience sampling method data. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Dual growth of adolescent smoking and drinking: evidence for an interaction between the mu-opioid receptor (OPRM1) A118G polymorphism and sex.

Smoking and alcohol use often co-occur during adolescence, but little is known about the codevelopment of these substances. In the search for etiological factors that help to explain the development of adolescent substance use patterns, studies have revealed substantial heritability for both alcohol use and smoking. In this regard, the µ-opioid receptor gene (OPRM1, chromosome 6q24-q25) has been linked to both substances. This study examined the predictive relationships between initial level and growth of smoking and drinking in 311 early adolescents (13-15 years old) over a 4-year period. In addition, the effects of the A118G polymorphism of the OPRM1 gene on the initial values and the development over time of alcohol use and smoking were assessed. Finally, as prevalence and heritability estimates for both alcohol- and smoking-related behaviors differ between males and females, OPRM1 by sex interactions were tested. We found that high initial levels of early adolescent alcohol consumption were related to a stronger increase in smoking levels over time. In contrast, high initial levels of smoking were not related to growth of alcohol use. No main OPRM1 effects were found, but sex-specificity of the gene was found for smoking development. Male A-allele carriers showed a faster development in smoking behavior, whereas in females, the G-allele led to a faster development in smoking. Thus, in addition to high levels of alcohol as a risk factor for the development of smoking behavior, sex-specific effects exist for OPRM1, which may additionally have consequences for the development of adolescent smoking.

Adolescents' food intake changes during the COVID-19 pandemic: The moderating role of pre-pandemic susceptibility, COVID-19 related stressors, and the social food context.

Although insight in how adolescents' food intake is affected by the COVID-19 pandemic is critical, knowledge is limited. Hence, this longitudinal study (N = 691, Mage = 14.30, SDage = 0.62; 52.5% female) investigated changes in adolescents' unhealthy (sugar-sweetened beverages, sweet snacks, savoury snacks) and healthy (fruit and vegetables) food intake (in total, obtained from home, and from outside the home) from pre-pandemic (Spring 2019) to the first lockdown (Spring 2020) and to six months later (Fall 2020). Moreover, several moderating factors were assessed. Results showed that the intake of unhealthy and healthy food in total and obtained from outside the home decreased during the lockdown. Six months later, unhealthy food intake returned to pre-pandemic levels, while healthy food intake remained lower. COVID-19 stressful life events and maternal food intake further qualified these longer-term changes in intake of sugar-sweetened beverages and fruit and vegetables, respectively. Future work is warranted to elucidate longer-term COVID-19 effects on adolescents' food intake.

University students' (binge) drinking during COVID-19 lockdowns: An investigation of depression, social context, resilience, and changes in alcohol use.

RATIONALE: The first COVID-19 lockdown impacted the social life and behaviors of university students, such as alcohol use. While previous studies have reported changes in students' alcohol use during the lockdown, knowledge of risk groups like binge drinkers is limited. OBJECTIVE: The purpose of this study is to investigate how the first lockdown impacted the alcohol use of university students who were regular binge drinkers before the lockdown. METHODS: Cross-sectional data were used to explore self-reported changes in alcohol use and associated psychosocial effects in regular binge drinking versus regular drinking university students (N = 7355) during the first COVID-19 lockdown (Spring 2020) in the Netherlands. RESULTS: University students generally drank less alcohol and reduced binge drinking behaviors during the lockdown. Being a binge drinker who increased/maintained alcohol use, or a regular drinker who increased, was associated with older age, fewer servings of alcohol per week before COVID-19, higher contact with friends, and not living with parents. Among regular binge drinkers, men increased their alcohol use during the lockdown significantly more than women. Among regular drinkers, those with high depressive symptoms and low resilience had increased alcohol use. CONCLUSIONS: These findings give insight into significant changes in drinking behaviors among university students during the first COVID-19 lockdown. More importantly, it underscores the need to reckon vulnerable students considering drinking type and associated psychosocial variables for increasing or maintaining higher alcohol use during societal stress periods. In the present study, an unexpected at-risk group emerged among regular drinkers who increased alcohol use during the lockdown in association with their mental state (i.e., depression and resilience). As the COVID-19 pandemic, and the possibility of similar scenarios in the future, is still present in the current student life, specific preventive strategies and interventions should be targeted accordingly.

Genome-wide association uncovers shared genetic effects among personality traits and mood states.

Measures of personality and psychological distress are correlated and exhibit genetic covariance. We conducted univariate genome-wide SNP (~2.5 million) and gene-based association analyses of these traits and examined the overlap in results across traits, including a prediction analysis of mood states using genetic polygenic scores for personality. Measures of neuroticism, extraversion, and symptoms of anxiety, depression, and general psychological distress were collected in eight European cohorts (n ranged 546-1,338; maximum total n = 6,268) whose mean age ranged from 55 to 79 years. Meta-analysis of the cohort results was performed, with follow-up associations of the top SNPs and genes investigated in independent cohorts (n = 527-6,032). Suggestive association (P = 8 × 10(-8)) of rs1079196 in the FHIT gene was observed with symptoms of anxiety. Other notable associations (P < 6.09 × 10(-6)) included SNPs in five genes for neuroticism (LCE3C, POLR3A, LMAN1L, ULK3, SCAMP2), KIAA0802 for extraversion, and NOS1 for general psychological distress. An association between symptoms of depression and rs7582472 (near to MGAT5 and NCKAP5) was replicated in two independent samples, but other replication findings were less consistent. Gene-based tests identified a significant locus on chromosome 15 (spanning five genes) associated with neuroticism which replicated (P < 0.05) in an independent cohort. Support for common genetic effects among personality and mood (particularly neuroticism and depressive symptoms) was found in terms of SNP association overlap and polygenic score prediction. The variance explained by individual SNPs was very small (up to 1%) confirming that there are no moderate/large effects of common SNPs on personality and related traits.

[A cohort-comparison of food intake, lifestyle and social-emotional health of adolescents before and during the corona crisis]. / Een cohortvergelijking van eetgedrag, leefstijl en sociaal-emotionele gezondheid bij jongeren vóór en tijdens de coronacrisis.

The corona crisis can be considered a 'natural experiment', in which the social context has changed dramatically. It is largely unknown how adolescents respond to this, and which behaviors change. We have compared a cohort of ninth graders (N = 177, M age = 15.00) from secondary schools before the corona crisis (Spring 2019) with a demographically comparable group of ninth graders (N = 188, M age = 14.95) during the first lockdown (Spring 2020). We compared the domains food intake, lifestyle, and social-emotional health between both cohorts, and we examined the associations within and between the domains for both cohorts. Sweet snack intake from home, alcohol use, and loneliness were higher in the corona cohort compared to before the corona crisis (non-significant after correction). The intake of fruit from home, of sugar-sweetened beverages and unhealthy snacks from outside the home, and of moderate and vigorous physical activity occurred less frequently during the lockdown. Relationship satisfaction with parents, happiness, and stress from school were lower compared to before the lockdown. Smoking, stress at home, and relationship satisfaction with their best friend were equal in both cohorts. The pattern of associations within and between domains differed. More research is needed to delineate how resilient youth are on the long-term, and which youth need support to bounce back.

The dopamine D2 receptor gene, perceived parental support, and adolescent loneliness: longitudinal evidence for gene-environment interactions.

BACKGROUND: Loneliness is a common problem in adolescence. Earlier research focused on genes within the serotonin and oxytocin systems, but no studies have examined the role of dopamine-related genes in loneliness. In the present study, we focused on the dopamine D2 receptor gene (DRD2). METHODS: Associations among the DRD2, sex, parental support, and loneliness were examined in a longitudinal study spanning five annual waves (N = 307). RESULTS: Using Latent Growth Curve Modeling, DRD2 genotype was not directly related to loneliness. Interactions were found between parental support and DRD2 genotype, showing that adolescents with the A2A2 genotype who perceived little support from their parents had the highest baseline levels of loneliness. Adolescents with an A1 allele were not susceptible to the rewarding effect of parental support. CONCLUSIONS: The present study is the first to examine the role of the DRD2 genotype in loneliness. Our results contribute to a further understanding of the environmental and genetic basis of loneliness in adolescence.