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Clin Transplant ; 23(5): 692-9, 2009.
Artículo en Inglés | MEDLINE | ID: mdl-19473203

RESUMEN

Hepatic hemodynamic changes in grafts after living donor liver transplantation (LDLT) are complicated. In this study, computed tomography (CT) perfusion parameter values, especially portal vein perfusion (PVP), was retrospectively analyzed in recipients both with and without small-for-size syndrome (SFSS). PVP was significantly higher in non-SFSS recipients on post-operative day (POD) 14 or 28 than in normal donors before donation (p < 0.001 and p = 0.008, respectively), but it significantly decreased between 14 and 28 days post-operatively (p = 0.007). There was a significant inverse correlation between graft-to-recipient spleen size ratio and PVP on POD 14 in non-SFSS group (r = -0.545, p = 0.002). Furthermore, PVP in the SFSS group was significantly greater than in the non-SFSS group on POD 14 (p = 0.042). In conclusion, we successfully evaluated normal hemodynamic changes in grafts without SFSS by CT perfusion examination. To our knowledge, this is the first study on hemodynamic changes of living donor liver grafts using CT technique.


Asunto(s)
Trasplante de Hígado , Hígado/irrigación sanguínea , Hígado/diagnóstico por imagen , Donadores Vivos , Tomografía Computarizada por Rayos X , Adulto , Anciano , Ensayo de Inmunoadsorción Enzimática , Femenino , Supervivencia de Injerto , Hemodinámica , Humanos , Masculino , Persona de Mediana Edad , Perfusión , Reacción en Cadena de la Polimerasa , Pronóstico , Estudios Retrospectivos , Resultado del Tratamiento , Adulto Joven
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