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Exp Cell Res ; 441(2): 114172, 2024 Aug 15.
Artículo en Inglés | MEDLINE | ID: mdl-39053869

RESUMEN

In recent years, the impact of age-related diseases on human health has become increasingly severe, and developing effective drugs to deal with these diseases has become an urgent task. Considering the essential regulatory role of hydrogen sulfide (H2S) in these diseases, it is regarded as a promising target for treatment. H2S is a novel gaseous transmitter involved in many critical physiological activities, including anti-oxidation, anti-inflammation, and angiogenesis. H2S also regulates cell activities such as cell proliferation, migration, invasion, apoptosis, and autophagy. These regulatory effects of H2S contribute to relieving and treating age-related diseases. In this review, we mainly focus on the pathogenesis and treatment prospects of H2S in regulating age-related diseases.


Asunto(s)
Envejecimiento , Sulfuro de Hidrógeno , Sulfuro de Hidrógeno/metabolismo , Sulfuro de Hidrógeno/farmacología , Humanos , Envejecimiento/metabolismo , Animales , Autofagia/efectos de los fármacos , Apoptosis/efectos de los fármacos , Proliferación Celular/efectos de los fármacos
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