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1.
Micromachines (Basel) ; 12(1)2021 Jan 05.
Artículo en Inglés | MEDLINE | ID: mdl-33466564

RESUMEN

The photoelectric hybrid network has been proposed to achieve the ultrahigh bandwidth, lower delay, and less power consumption for chip multiprocessor (CMP) systems. However, a large number of optical elements used in optical networks-on-chip (ONoCs) generate high transmission loss which will influence network performance severely and increase power consumption. In this paper, the Dijkstra algorithm is adopted to realize adaptive routing with minimum transmission loss of link and reduce the output power of the link transmitter in mesh-based ONoCs. The numerical simulation results demonstrate that the transmission loss of a link in optimized power control based on the Dijkstra algorithm could be maximally reduced compared with traditional power control based on the dimensional routing algorithm. Additionally, it has a greater advantage in saving the average output power of optical transmitter compared to the adaptive power control in previous studies, while the network size expands. With the aid of simulation software OPNET, the network performance simulations in an optimized network revealed that the end-to-end (ETE) latency and throughput are not vastly reduced in regard to a traditional network. Hence, the optimized power control proposed in this paper can greatly reduce the power consumption of s network without having a big impact on network performance.

2.
Micromachines (Basel) ; 11(11)2020 Nov 09.
Artículo en Inglés | MEDLINE | ID: mdl-33182518

RESUMEN

Optical networks-on-chips (ONoCs) is an effective and extensible on-chip communication technology, which has the characteristics of high bandwidth, low consumption, and low delay. In the design process of ONoCs, power loss is an important factor for limiting the scalability of ONoCs. Additionally, the optical signal-to-noise ratio (OSNR) is an index to measure the quality of ONoCs. Nowadays, the routing algorithm commonly used in ONoCs is the dimension-order routing algorithm, but the routing paths selected by the algorithm have high power loss and crosstalk noise. In this paper, we propose a 5×5 all-pass optical router model for two-dimensional (2-D) mesh-based ONoCs. Based on the general optical router model and the calculation models of power loss and crosstalk noise, a novel algorithm is proposed in ordder to select the routing paths with the minimum power loss. At the same time, it can ensure that the routing paths have the approximately optimal OSNR. Finally, we employ the Cygnus optical router to verify the proposed routing algorithm. The results show that the algorithm can effectively reduce the power loss and improve the OSNR in the case of network sizes of 5×5 and 6×6. With the increase of the optical network scale, the algorithm can perform better in reducing the power loss and raising the OSNR.

3.
Zhongguo Ying Yong Sheng Li Xue Za Zhi ; 33(1): 51-55, 2017 Jan 08.
Artículo en Zh | MEDLINE | ID: mdl-29926607

RESUMEN

OBJECTIVE: To investigate the effects of Shiquanyuzhentang (Traditional Chinese Medicine) on the immunologic function of tu-mor-bearing mice and its mechanism of antitumor. METHODS: Thirty SPF grade male Kunming mice transplanted with H22 hepatocellular carci-noma were divided into three groups randomly:model group,positive control group and Shiquanyuzhentang group(n=10). Another 10 mice were selected as normal control group. Normal control group and model group received normal saline and distilled water supplementation by 10 mL/kg everyday. Positive control group and Shiquanyuzhentang group received Shengyi(80 mg/ml)and Shiquanyuzhentang decoction at the doses of 8 g/kg and 18 g/kg respectively everyday. After 14 days of continuous administration, the mice were killed and the thymus, spleen index, tumor inhibition rate,peripheral blood leukocytes,lymphocyte content,cell percentage of T cell subsets CD3, CD4, CD8,interleukin 2 (IL-2)in serum,tumor necrosis factor-α(TNF-α),interferon ß(IFN-ß) content,lymphocyte proliferation ability and NK cell were measured. RESULTS: Compared with normal control group, the weight of mice and thymus and spleen index of the Shiquanyuzhentang group were increased significantly(P<0.05);leukocyte and lymphocyte CD3、CD4、CD8 and TNF-α were increased greatly(P<0. 05),IL-2 and IFN-ß were de-creased significantly(P<0.05). Compared with model group,thymus and spleen index of Shiquanyuzhentang group were increased significant-ly(P<0.05);leukocyte and lymphocyte CD3、CD4、IL-2、IFN-ß and TNF-α of Shiquanyuzhentang group were increased significantly(P<0. 05),CD8 content was decreased significantly(P<0.05);NK cell and lymphocyte proliferation were increased significantly(P<0.05). CONCLUSIONS: Shiquanyuzhentang can promote the growth of immune organs in mice bearing H22, enhance immune function and is beneficial to the recovery of tumor body.


Asunto(s)
Carcinoma Hepatocelular/inmunología , Medicamentos Herbarios Chinos/farmacología , Neoplasias Experimentales/inmunología , Animales , Carcinoma Hepatocelular/tratamiento farmacológico , Interferón gamma/inmunología , Interleucina-2/inmunología , Células Asesinas Naturales/inmunología , Masculino , Ratones , Neoplasias Experimentales/tratamiento farmacológico , Bazo/inmunología , Subgrupos de Linfocitos T/inmunología , Timo/inmunología , Factor de Necrosis Tumoral alfa/inmunología
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