Carcinogenic effects of different nitroso-compounds in chinese hamsters: N-dibutylnitrosamine and N-nitrosomethylurea.
Cancer Lett
; 1(4): 183-8, 1976 Mar.
Article
en En
| MEDLINE
| ID: mdl-1016942
ABSTRACT
Three hundred and twenty Chinese hamsters (Cricetulus griseus) (CH) were subcutaneously (s.c.) treated with 1/5, 1/10 or 1/20 the mean lethal dose (LD50) of N-dibutylnitrosamine (DBN) or N-nitrosomethylurea (NMU). In several respects these two substances produced the same organotropy in the CH as in the Syrian golden (SGH) and European hamsters (EH). DBN prolonged lung tumours and neoplasms of the injection site. NMU induced tumours of the injection site only.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Neoplasias Pulmonares
/
Metilnitrosourea
/
Neoplasias Experimentales
/
Nitrosaminas
/
Compuestos de Nitrosourea
Límite:
Animals
Idioma:
En
Revista:
Cancer Lett
Año:
1976
Tipo del documento:
Article