Betaine in wine: answer to the French paradox?
Med Hypotheses
; 53(5): 383-5, 1999 Nov.
Article
en En
| MEDLINE
| ID: mdl-10616037
ABSTRACT
In France, a diet high in saturated fat and cholesterol is associated with low coronary artery disease mortality and it may be that drinking wine is protective against ischemic heart disease. Recent studies suggest that high plasma homocysteine concentrations are an independent risk factor for coronary, cerebral and peripheral arterial occlusive diseases. One of several routes for metabolism of homocysteine involves methylation using betaine as the methyl donor. Betaine is often added to less expensive wine when beet sugar is used to increase alcohol content. We found that many commercial wines contain betaine; an average glass of wine contains approximately 3 mg betaine. This small amount is less than the dose used to lower homocysteine in patients with genetic forms of hyperhomocysteinemia, but we do not know whether humans with modest elevations of homocysteine would be influenced by this dose.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Arteriopatías Oclusivas
/
Vino
/
Betaína
Tipo de estudio:
Risk_factors_studies
Límite:
Humans
Idioma:
En
Revista:
Med Hypotheses
Año:
1999
Tipo del documento:
Article
País de afiliación:
Estados Unidos