Evaluation of giant-cell deposits on foldable intraocular lenses after combined cataract and glaucoma surgery.
J Cataract Refract Surg
; 26(6): 817-23, 2000 Jun.
Article
en En
| MEDLINE
| ID: mdl-10889425
ABSTRACT
PURPOSE:
To compare the incidence of inflammatory giant-cell deposits (IGCDs) on various foldable intraocular lenses (IOLs) after combined cataract and glaucoma surgery.SETTING:
The Phillips Eye Institute, Minneapolis, Minnesota, USA.METHODS:
In this prospective randomized clinical trial, 128 patients were randomized to receive a single-piece, first-generation silicone lens (n = 36); a 3-piece acrylic lens (n = 40); or 3-piece, second-generation silicone lens (n = 52). All patients had combined phacoemulsification and trabeculectomy with mitomycin-C by 1 surgeon using a standardized technique. Dilated biomicroscopy was used to identify and quantitate IGCDs on the surface of the IOLs using a 6-point grading scale.RESULTS:
Inflammatory giant-cell deposits were identified on 21 of 128 IOLs. Lens design was the most significant risk factor for deposit formation (P =.004). Inflammatory giant-cell deposits were most common in the first-generation silicone plate lens group (33%), less common in the acrylic lens group (15%), and least common in the 3-piece, second-generation silicone group (5.8%). Density of the deposits was significantly greater on the plate lens than the acrylic or the 3-piece silicone lenses (P <.0001). Although IOL design was the most significant risk factor for IGCD formation, other significant risk factors included intraoperative pupil stretch (P =.02) and preoperative miotic use (P =.04).CONCLUSION:
Inflammatory giant-cell deposit formation was significantly greater on first-generation silicone plate IOLs than on acrylic or second-generation silicone IOLs. The deposits were somewhat more common on acrylic IOLs than on second-generation silicone IOLs. However, this difference was not clinically or statistically significant.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Catarata
/
Trabeculectomía
/
Células Gigantes de Cuerpo Extraño
/
Glaucoma
/
Reacción a Cuerpo Extraño
/
Facoemulsificación
/
Lentes Intraoculares
Tipo de estudio:
Clinical_trials
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
En
Revista:
J Cataract Refract Surg
Asunto de la revista:
OFTALMOLOGIA
Año:
2000
Tipo del documento:
Article
País de afiliación:
Estados Unidos