Y chromosome sequence variation and the history of human populations.
Nat Genet
; 26(3): 358-61, 2000 Nov.
Article
en En
| MEDLINE
| ID: mdl-11062480
ABSTRACT
Binary polymorphisms associated with the non-recombining region of the human Y chromosome (NRY) preserve the paternal genetic legacy of our species that has persisted to the present, permitting inference of human evolution, population affinity and demographic history. We used denaturing high-performance liquid chromatography (DHPLC; ref. 2) to identify 160 of the 166 bi-allelic and 1 tri-allelic site that formed a parsimonious genealogy of 116 haplotypes, several of which display distinct population affinities based on the analysis of 1062 globally representative individuals. A minority of contemporary East Africans and Khoisan represent the descendants of the most ancestral patrilineages of anatomically modern humans that left Africa between 35,000 and 89,000 years ago.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Filogenia
/
Cromosoma Y
/
Hominidae
/
Etnicidad
/
Evolución Molecular
Tipo de estudio:
Prognostic_studies
Límite:
Animals
/
Humans
/
Male
País/Región como asunto:
Africa
Idioma:
En
Revista:
Nat Genet
Asunto de la revista:
GENETICA MEDICA
Año:
2000
Tipo del documento:
Article