Improved incidental memory with nicotine after semantic processing, but not after phonological processing.
Psychopharmacology (Berl)
; 153(2): 258-63, 2001 Jan 01.
Article
en En
| MEDLINE
| ID: mdl-11205428
ABSTRACT
RATIONALE A number of lines of evidence suggest that a nicotinic cholinergic system is mediating attentional processing. However, the evidence is less clear for a nicotinic system being involved in mnemonic processing. OBJECTIVES:
The present study investigated the effects of nicotine on memory using a depth of processing paradigm.METHODS:
A double-blind design was used with participants (n = 40) smoking either a nicotine containing cigarette (n = 20) and a denicotinized cigarette (n = 20). After smoking, each set of these participants was further subdivided into two groups (n = 10 for each). One group were presented with a series of trials each beginning with the presentation of a "decision word" which they had to say whether it represented something which was living or non-living (semantic-orienting). The second group had to say whether the word had one syllable or two syllables (phonological or non-semantic orienting condition). This decision was followed by a word in coloured ink whose colour participants were required to name as quickly as possible. On completion of the whole task the participants were given an unexpected free recall test.RESULTS:
The nicotine-containing cigarette reduced the latencies for decision-making and colour naming in comparison with the denicotinized cigarette. The free recall test showed that nicotine-containing cigarette increased the number of words remembered, but only for the semantic-orienting condition and not the non-semantic condition.CONCLUSIONS:
There is a nicotinic cholinergic system that mediates effortful processing. It can be deployed for attentional processing, including the associative processing required for memory encoding.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Semántica
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Percepción del Habla
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Agonistas Nicotínicos
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Memoria
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Procesos Mentales
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Nicotina
Tipo de estudio:
Clinical_trials
/
Prognostic_studies
Límite:
Adolescent
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Adult
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Female
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Humans
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Male
Idioma:
En
Revista:
Psychopharmacology (Berl)
Año:
2001
Tipo del documento:
Article
País de afiliación:
Reino Unido