Depressed baroreflex sensitivity in patients with Alzheimer's and Parkinson's disease.
Neurobiol Aging
; 22(3): 435-8, 2001.
Article
en En
| MEDLINE
| ID: mdl-11378250
ABSTRACT
Parkinson's disease (PD) and Alzheimer's dementia (AD) are often associated with an autonomic neuropathy. The extent of autonomic involvement, however is poorly defined and unpredictable. In order to assess the autonomic cardiovascular regulation baroreflex sensitivity (BRS) was determined non-invasively in 23 patients (age 65 +/- 9.3 years) with PD and 24 patients with AD (age 72.3 +/- 7.2 years). The results were compared with those on 22 healthy age- and sex-matched volunteers. Patients with PD and AD exhibited marked abnormalities in cardiovascular autonomic reflex regulation showed by markedly depressed BRS. The possible predictive value of centrally based depression of baroreflex sensitivity necessitates further studies.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Enfermedad de Parkinson
/
Barorreflejo
/
Enfermedad de Alzheimer
Tipo de estudio:
Diagnostic_studies
Límite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Neurobiol Aging
Año:
2001
Tipo del documento:
Article
País de afiliación:
Hungria