Association analysis of NOTCH4 loci in schizophrenia using family and population-based controls.
Nat Genet
; 28(2): 126-8, 2001 Jun.
Article
en En
| MEDLINE
| ID: mdl-11381257
ABSTRACT
A genetic association between NOTCH4 and schizophrenia has previously been proposed. Unsing all markers previously shown to be associated, we found no evidence for such in three independent family-based samples (n=519 parent-offspring trios), and a case-control sample derived from the same ethnic background as the original observation. These data strongly suggest that NOTCH4 is not a significant susceptibility allele for schizophrenia.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Esquizofrenia
/
Desequilibrio de Ligamiento
/
Proteínas Proto-Oncogénicas
/
Receptores de Superficie Celular
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Humans
País/Región como asunto:
Europa
Idioma:
En
Revista:
Nat Genet
Asunto de la revista:
GENETICA MEDICA
Año:
2001
Tipo del documento:
Article
País de afiliación:
Estados Unidos