Reed-Sternberg-like cells in nodular lymphoma involving the bone marrow.
Am J Clin Pathol
; 63(6): 779-85, 1975 Jun.
Article
en En
| MEDLINE
| ID: mdl-1173738
ABSTRACT
McKenna, Robert W., and Brunning, Richard D. Reed-Sternberg-like cells in nodular lymphoma involving the bone marrow. Am JClin Pathol 63 779-785, 1975. Two patients with cells indistinguishable from Reed-Sternberg cells in bone marrow lesions of nodular poorly differentiated lymphocytic lymphoma are described. Both patients had lymph node biopsies showing nodular lymphoma. Bone marrow and blood involvement with the lymphoma was demonstrated at the time of initial diagnosis. Reed-Sternberg-like cells were not demonstrated in either case until later in the course of the disease, after the patients had been treated with numerous chemotherapeutic agents. Other similarities of bone marrow involvement with nodular lymphoma to Hodgkin's disease of the bone marrow are noted. The origin of the Reed-Sternberg-like cells in nodular lymphoma is not clear, but they could result from morphologicalteration of lymphoma cells by chemotherapy. The finding of Reed-Sternberg cells in bone marrow lesions should be interpreted with caution unless diagnostic biopsy material from other sites is available for study. (Key words Bone marrow lymphoma' nodular lymphoma; Reed-Sternberg cells).
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Médula Ósea
/
Linfoma no Hodgkin
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Células de la Médula Ósea
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Histiocitos
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Ganglios Linfáticos
Tipo de estudio:
Diagnostic_studies
Límite:
Adult
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Am J Clin Pathol
Año:
1975
Tipo del documento:
Article