Exercise-induced acute renal failure with renal hypouricemia: a case report and a review of the literature.
Clin Nephrol
; 58(4): 313-6, 2002 Oct.
Article
en En
| MEDLINE
| ID: mdl-12400848
ABSTRACT
A previously healthy 16-year-old boy developed acute renal failure following a track race at a local athletic meeting. Several hours after the run, he expressed pain in the loins with nausea and vomiting. After 3 sessions of hemodialysis, he was referred to our hospital. On admission, serum creatinine was elevated to 2.3 mg/dl without an increase in serum uric acid level. After recovery from acute renal failure (ARF), hypouricemia (0.7 mg/dl) became evident in the patient. One year later, he suffered from ARF after a track race with the highest creatinine levels of 1.1 mg/dl. In order to clarify the cause and prognosis of ARF with renal hypouricemia, we summarized the clinical features in 18 patients previously described and our patient. Serum uric acid levels after recovery from ARF were below 1.0 mg/dl in all patients. Renal biopsy in 9 patients showed acute tubular necrosis in 8 patients and uric acid nephropathy in 1. The short-term prognosis of these patients seemed good, although 5 patients needed to undergo hemodialysis in their ARF courses. However, the recurrence of ARF episodes occurred in 6 patients (31.6%) including our patient, indicating that prevention of ARF might be necessary in these patients. More information is required to establish guidance for prevention of ARF.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Ácido Úrico
/
Ejercicio Físico
/
Lesión Renal Aguda
Tipo de estudio:
Guideline
/
Prognostic_studies
Límite:
Adolescent
/
Humans
/
Male
Idioma:
En
Revista:
Clin Nephrol
Año:
2002
Tipo del documento:
Article
País de afiliación:
Japón