[Epidemiology of infections associated to "Burkholderia cepacia complex" in the course of cystic fibrosis]. / Epidémiologie des infections provoquées par les bactéries du "complexe Burkholderia cepacia" au course de la mucoviscidose.
Arch Pediatr
; 11(4): 360-6, 2004 Apr.
Article
en Fr
| MEDLINE
| ID: mdl-15139322
ABSTRACT
Within a few years bacteriological knowledge on Burkholderia cepacia species has progressed considerably. Within bacterial classification (taxonomy), B. cepacia gathers eight species and one species on standby of nomenclature (genomovar VI); the whole of these species constitutes the "B. cepacia complex" or B. cepacia "sensu lato" and the denomination B. cepacia "sensu stricto" is attributed to the genomovar I. These new data call into question the knowledge on the clinic and the epidemiology of B. cepacia "sensu lato" infection in the course of cystic fibrosis. Among these newly described species, B. cenocepacia (formerly genomovar III) and B. multivorans (formerly genomovar II) are the most frequent species and together they represent more than 90% of infections associated to "B. cepacia complex" in the course of cystic fibrosis. B. cenocepacia is often associated to the "cepacia syndrome" which is characterized as a fatal necrotizing pneumonia with bacteremia. The progress of molecular epidemiology allowed the description of bacterial clones of which some are highly transmissible from person-to-person. Their distribution varies according to the species and the geography. The identification of these new species appears particularly difficult and, by the fact, the data on taxonomy and molecular epidemiology can be provided only by highly specialized reference centers.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Infecciones por Burkholderia
/
Fibrosis Quística
/
Complejo Burkholderia cepacia
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
/
Screening_studies
Límite:
Humans
Idioma:
Fr
Revista:
Arch Pediatr
Año:
2004
Tipo del documento:
Article
País de afiliación:
Francia