The impact of comorbidity on the survival of postmenopausal women with breast cancer.
J Cancer Res Clin Oncol
; 130(11): 664-70, 2004 Nov.
Article
en En
| MEDLINE
| ID: mdl-15300426
ABSTRACT
PURPOSE:
The aim was to assess the impact of comorbidity on survival of postmenopausal women with breast cancer diagnosis in the period 1995-1997.METHODS:
The level of comorbidity was described by the methods suggested by Satariano and Charlson. Cox's proportional hazard models were used to explore the impact of comorbidity on all-cause mortality.RESULTS:
After a median follow-up time of 52 months, an increasing level of comorbidity was associated with a higher all-cause mortality. Compared to patients with-out comorbid conditions, the hazard ration of death (HR) was 1.2 (95% CI 0.8-1.7) for Satariano index 1 and HR 2.3 (95% CI 1.5-3.5) for Satariano index >or=2, and HR 1.6 and 2.1 for the Charlson comorbidity index, respectively. Independent of comorbidity, the treatment pattern had a strong impact on survival. The level of comorbidity has an influence on the 3-year survival of postmenopausal women with breast cancer.CONCLUSIONS:
Long-term follow-up is required to appraise these findings in relation to treatment strategies.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Neoplasias de la Mama
/
Posmenopausia
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Aged
/
Aged80
/
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
J Cancer Res Clin Oncol
Año:
2004
Tipo del documento:
Article
País de afiliación:
Alemania