Depletion of neuroendocrine cells in rectal biopsy specimens from HIV positive patients.
J Clin Pathol
; 45(6): 524-7, 1992 Jun.
Article
en En
| MEDLINE
| ID: mdl-1624601
ABSTRACT
AIMS:
To compare the density of neuroendocrine cells in rectal biopsy specimens from human immunodeficiency virus (HIV) infected individuals with that of a control group.METHODS:
Neuroendocrine cells in rectal biopsies were identified using an immunohistochemical stain for chromogranin and subsequently quantified using a method of linear intercept.RESULTS:
Neuroendocrine cells were found to be significantly decreased in the HIV positive group.CONCLUSIONS:
Loss of neuroendocrine cells may contribute to apoptotic bodies seen in this condition. This could be related to infection of these cells with HIV and could contribute to diarrhoeal disease in HIV infection.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Recto
/
Infecciones por VIH
/
Sistemas Neurosecretores
Límite:
Humans
/
Male
Idioma:
En
Revista:
J Clin Pathol
Año:
1992
Tipo del documento:
Article