Response of Aedes aegypti (Diptera: Culicidae) larvae to three xenobiotic exposures: larval tolerance and detoxifying enzyme activities.
Environ Toxicol Chem
; 25(2): 470-6, 2006 Feb.
Article
en En
| MEDLINE
| ID: mdl-16519308
ABSTRACT
The ability of mosquito larvae to tolerate toxic compounds (temephos, Bacillus thuringiensis var. israelensis, toxic vegetable leaf litter) was examined on a laboratory larval strain of Aedes aegypti L. Bioassays and detoxifying enzyme activity measurements were performed to compare tolerance/resistance capacities. The possibility of a functional plasticity of detoxifying equipment was investigated through experimental determination of the inductive effect of each xenobiotic within a given generation. In the same way, the selective effect of a toxic leaf litter was also investigated along successive generations. Results revealed that differential cytochrome P450 monooxygenase, esterase, and glutathione S-transferase activity levels correlated with the bioassay results. Both induction and selection increased larval tolerance to the xenobiotics used and increased the levels of larval detoxifying enzyme activities.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Xenobióticos
/
Aedes
/
Tolerancia a Medicamentos
Límite:
Animals
Idioma:
En
Revista:
Environ Toxicol Chem
Año:
2006
Tipo del documento:
Article
País de afiliación:
Francia