On the mechanism underlying (23S)-25-dehydro-1alpha(OH)-vitamin D3-26,23-lactone antagonism of hVDRwt gene activation and its switch to a superagonist.

Mizwicki, Mathew T; Bula, Craig M; Mahinthichaichan, Paween; Henry, Helen L; Ishizuka, Seiichi; Norman, Anthony W

Mizwicki, Mathew T; Bula, Craig M; Mahinthichaichan, Paween; Henry, Helen L; Ishizuka, Seiichi; Norman, Anthony W.

Afiliación

Mizwicki MT; Department of Biochemistry, University of California, Riverside, California 92521. Electronic address: mathew.mizwicki@ucr.edu.
Bula CM; Department of Biochemistry, University of California, Riverside, California 92521.
Mahinthichaichan P; Department of Biochemistry, University of California, Riverside, California 92521.
Henry HL; Department of Biochemistry, University of California, Riverside, California 92521.
Ishizuka S; Department of Bone and Calcium Metabolism, Teijin Institute for Biomedical Research, 4-3-2 Asahigaoka, Hino, Tokyo 191-8512, Japan.
Norman AW; Department of Biochemistry, University of California, Riverside, California 92521.

J Biol Chem ; 284(52): 36292-36301, 2009 Dec 25.

Article en En | MEDLINE | ID: mdl-19801650

Asunto(s)

Calcitriol/antagonistas & inhibidores; Calcitriol/química; Modelos Moleculares; Receptores de Calcitriol/antagonistas & inhibidores; Receptores de Calcitriol/química; Sitios de Unión; Calcitriol/metabolismo; Humanos; Mutación; Estructura Secundaria de Proteína/genética; Receptores de Calcitriol/genética; Receptores de Calcitriol/metabolismo; Relación Estructura-Actividad

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Calcitriol / Modelos Moleculares / Receptores de Calcitriol Límite: Humans Idioma: En Revista: J Biol Chem Año: 2009 Tipo del documento: Article

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