Electroconvulsive therapy is equally effective in unipolar and bipolar depression.
Acta Psychiatr Scand
; 121(6): 431-6, 2010 Jun.
Article
en En
| MEDLINE
| ID: mdl-19895623
ABSTRACT
OBJECTIVE:
To determine the relative efficacy of electroconvulsive therapy (ECT) in the treatment of bipolar (BP) and unipolar (UP) depressive illness and clarify its role in BP depression.METHOD:
Patients referred for ECT with both UP and BP depressions. [classified by Structured Clinical Interview for DSM (SCID-I) criteria for history of mania] were included in a multi-site collaborative, double-masked, randomized controlled trial of three electrode placements - right unilateral, bifrontal or bitemporal - in a permutated block randomization scheme.RESULTS:
Of 220 patients, 170 patients (77.3%) were classified as UP and 50 (22.7%) as BP depression in the intent-to-treat sample. The remission and response rates and numbers of ECT for both groups were equivalent.CONCLUSION:
Both UP and BP depressions remit with ECT. Polarity is not a factor in the response rate. In this sample ECT did not precipitate mania in depressed patients. Treatment algorithms for UP and BP depression warrant re-evaluation.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Trastorno Bipolar
/
Trastorno Depresivo Mayor
/
Terapia Electroconvulsiva
Tipo de estudio:
Clinical_trials
/
Diagnostic_studies
/
Etiology_studies
/
Qualitative_research
Límite:
Adult
/
Female
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Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Acta Psychiatr Scand
Año:
2010
Tipo del documento:
Article
País de afiliación:
Estados Unidos