Alveolar proteinosis with hypersensitivity pneumonitis: a new clinical phenotype.
Respirology
; 15(8): 1197-202, 2010 Nov.
Article
en En
| MEDLINE
| ID: mdl-20920129
ABSTRACT
BACKGROUND AND OBJECTIVE:
The aim of the present study was to report the features of five patients with concurrent histopathological features of pulmonary alveolar proteinosis (PAP) and hypersensitivity pneumonitis (HP) and their high-resolution CT (HRCT) appearances.METHODS:
Patients with histopathological features of both HP and PAP on surgical lung biopsy referred for tertiary review were retrospectively identified. The pathology and HRCT images were semi-quantitatively scored to evaluate the relative contribution to HP and PAP.RESULTS:
Five patients had histopathological features of HP and PAP but had varied HRCT appearances. All had imaging features of PAP to a varying degree with two patients also showing characteristics of HP but three patients had ill-defined thickened interlobular septa, not typical of either disease.CONCLUSIONS:
We describe the coexistence of PAP and HP in five patients and discuss possible linkages between these two distinct pathologies.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Proteinosis Alveolar Pulmonar
/
Alveolitis Alérgica Extrínseca
Tipo de estudio:
Observational_studies
/
Prognostic_studies
Límite:
Adult
/
Aged
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Respirology
Año:
2010
Tipo del documento:
Article
País de afiliación:
Reino Unido