Contrast agent derived determination of the total circulating blood volume using magnetic resonance.
MAGMA
; 25(3): 215-22, 2012 Jun.
Article
en En
| MEDLINE
| ID: mdl-21928062
ABSTRACT
OBJECT Knowledge of the total circulating blood volume (TCBV) is essential for the treatment of a variety of medical conditions and blood disorders. To date, blood volume analysis is rarely carried out due to the disadvantages of available methods. Our aim was to develop a widely available, simple, fast, yet accurate method for the determination of the total circulating blood volume. MATERIALS AND METHODS:
Magnetic resonance (MR) is a well-established, non-invasive technique. In this article, we present a method that uses MR contrast agents for the determination of the blood volume. The dependence of MR relaxation times on the concentration of MR contrast agents allows the calculation of the volume the contrast agent has been diluted in.RESULTS:
In phantom and in vivo experiments we could demonstrate that TCBV can be determined with high accuracy and precision.CONCLUSION:
This work introduces a novel method for the determination of the total circulating blood volume using magnetic resonance contrast agents as tracers.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Volumen Sanguíneo
/
Determinación del Volumen Sanguíneo
/
Algoritmos
/
Imagen por Resonancia Magnética
/
Interpretación de Imagen Asistida por Computador
/
Gadolinio DTPA
/
Modelos Cardiovasculares
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Animals
Idioma:
En
Revista:
MAGMA
Asunto de la revista:
DIAGNOSTICO POR IMAGEM
Año:
2012
Tipo del documento:
Article
País de afiliación:
Alemania