Unusual insertion and deletion at codon 67 and 69 of HIV type 1 subtype C reverse transcriptase among first-line highly active antiretroviral treatment-failing South Indian patients: association with other resistance mutations.
AIDS Res Hum Retroviruses
; 28(12): 1763-5, 2012 Dec.
Article
en En
| MEDLINE
| ID: mdl-22404052
ABSTRACT
We report a high frequency of drug resistance mutations among patients with unusual insertions or deletions at the ß(3)-ß(4) hairpin-loop-coding region of HIV-1 subtype C reverse transcriptase, during failure of first-line antiretroviral therapy containing only reverse transcriptase inhibitors in Chennai, India.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Infecciones por VIH
/
Mutagénesis Insercional
/
VIH-1
/
Eliminación de Secuencia
/
Fármacos Anti-VIH
/
Terapia Antirretroviral Altamente Activa
/
Transcriptasa Inversa del VIH
Tipo de estudio:
Risk_factors_studies
Límite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
Asia
Idioma:
En
Revista:
AIDS Res Hum Retroviruses
Asunto de la revista:
SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS)
Año:
2012
Tipo del documento:
Article
País de afiliación:
India