[Study on the healing effect of pneumoconiosis with tetrandrine and massive whole-lung lavage].
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
; 30(1): 68-70, 2012 Jan.
Article
en Zh
| MEDLINE
| ID: mdl-22730694
ABSTRACT
OBJECTIVE:
To study the healing effect of pneumoconiosis with tetrandrine and massive whole-lung lavage.METHODS:
Choose 34 confirmed pneumoconiosis patients as drug treatment group and complex treatment group, and 17 tested workers as control group. Collected the content of TGF-beta1 and P III P which in these three investigated groups.RESULTS:
Drug treatment group and complex treatment group of patients improved the clinical symptoms and lung function Compared with Pretreatment, the FVC, FEV1.0, FEV1.0/FVC, MVV was obviously higher than those before treatment (P < 0.05). Complex treatment group than in the drug treatment group increased more significantly (P < 0.05). The level of TGF-beta1 and P III P was reduced after complex treatment (P < 0.05). Moreover,the level of TGF-beta1 and P III P in these patients are lower than in those patients treated with tetrandrine combined with whole lung lavage (P < 0.05).CONCLUSION:
Tetrandrine combined with whole-lung lavage could significantly retard the development of pneumoconiosis by lessening the TGF-beta1 and P III P in serum.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Neumoconiosis
/
Bencilisoquinolinas
Tipo de estudio:
Clinical_trials
Límite:
Adult
/
Humans
/
Male
/
Middle aged
Idioma:
Zh
Revista:
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
Asunto de la revista:
MEDICINA OCUPACIONAL
Año:
2012
Tipo del documento:
Article
País de afiliación:
China