X-ray imaging of tumor growth in live mice by detecting gold-nanoparticle-loaded cells.
Sci Rep
; 2: 610, 2012.
Article
en En
| MEDLINE
| ID: mdl-22934133
ABSTRACT
We show that sufficient concentrations of gold nanoparticles produced by an original synthesis method in EMT-6 and CT-26 cancer cells make it possible to detect the presence, necrosis and proliferation of such cells after inoculation in live mice. We first demonstrated that the nanoparticles do not interfere with the proliferation process. Then, we observed significant differences in the tumor evolution and the angiogenesis process after shallow and deep inoculation. A direct comparison with pathology optical images illustrates the effectiveness of this approach.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Nanopartículas del Metal
/
Rastreo Celular
/
Oro
/
Neoplasias
Tipo de estudio:
Diagnostic_studies
Límite:
Animals
Idioma:
En
Revista:
Sci Rep
Año:
2012
Tipo del documento:
Article
País de afiliación:
Taiwán