Increased chemosensitivity via targeting testicular nuclear receptor 4 (TR4)-Oct4-interleukin 1 receptor antagonist (IL1Ra) axis in prostate cancer CD133+ stem/progenitor cells to battle prostate cancer.

Yang, Dong-Rong; Ding, Xian-Fan; Luo, Jie; Shan, Yu-Xi; Wang, Ronghao; Lin, Shin-Jen; Li, Gonghui; Huang, Chiung-Kuei; Zhu, Jin; Chen, Yuhchyau; Lee, Soo Ok; Chang, Chawnshang

Yang, Dong-Rong; Ding, Xian-Fan; Luo, Jie; Shan, Yu-Xi; Wang, Ronghao; Lin, Shin-Jen; Li, Gonghui; Huang, Chiung-Kuei; Zhu, Jin; Chen, Yuhchyau; Lee, Soo Ok; Chang, Chawnshang.

Afiliación

Yang DR; George Whipple Laboratory for Cancer Research, Departments of Pathology, Urology, and Radiation Oncology and the Wilmot Cancer Center. University of Rochester Medical Center, Rochester, New York 14642; Department of Urology, Second Affiliated Hospital of Soochow University, Suzhou, 215004 China.
Ding XF; George Whipple Laboratory for Cancer Research, Departments of Pathology, Urology, and Radiation Oncology and the Wilmot Cancer Center. University of Rochester Medical Center, Rochester, New York 14642; Department of Urology, Sir Run Run Shaw Hospital of Zhejiang University, Hangzhou, 310016 China.
Luo J; George Whipple Laboratory for Cancer Research, Departments of Pathology, Urology, and Radiation Oncology and the Wilmot Cancer Center. University of Rochester Medical Center, Rochester, New York 14642.
Shan YX; Department of Urology, Second Affiliated Hospital of Soochow University, Suzhou, 215004 China.
Wang R; George Whipple Laboratory for Cancer Research, Departments of Pathology, Urology, and Radiation Oncology and the Wilmot Cancer Center. University of Rochester Medical Center, Rochester, New York 14642.
Lin SJ; George Whipple Laboratory for Cancer Research, Departments of Pathology, Urology, and Radiation Oncology and the Wilmot Cancer Center. University of Rochester Medical Center, Rochester, New York 14642.
Li G; Department of Urology, Sir Run Run Shaw Hospital of Zhejiang University, Hangzhou, 310016 China.
Huang CK; George Whipple Laboratory for Cancer Research, Departments of Pathology, Urology, and Radiation Oncology and the Wilmot Cancer Center. University of Rochester Medical Center, Rochester, New York 14642.
Zhu J; George Whipple Laboratory for Cancer Research, Departments of Pathology, Urology, and Radiation Oncology and the Wilmot Cancer Center. University of Rochester Medical Center, Rochester, New York 14642; Department of Urology, Second Affiliated Hospital of Soochow University, Suzhou, 215004 China.
Chen Y; George Whipple Laboratory for Cancer Research, Departments of Pathology, Urology, and Radiation Oncology and the Wilmot Cancer Center. University of Rochester Medical Center, Rochester, New York 14642.
Lee SO; Department of Urology, Second Affiliated Hospital of Soochow University, Suzhou, 215004 China. Electronic address: soook_lee@urmc.rochester.edu.
Chang C; George Whipple Laboratory for Cancer Research, Departments of Pathology, Urology, and Radiation Oncology and the Wilmot Cancer Center. University of Rochester Medical Center, Rochester, New York 14642; Sex Hormone Research Center, China Medical University/Hospital, Taichung 404, Taiwan. Electronic a

J Biol Chem ; 288(23): 16476-16483, 2013 Jun 07.

Article en En | MEDLINE | ID: mdl-23609451

Asunto(s)

Antígenos CD; Antineoplásicos Fitogénicos/farmacología; Resistencia a Antineoplásicos/efectos de los fármacos; Etopósido/farmacología; Glicoproteínas; Proteína Antagonista del Receptor de Interleucina 1/metabolismo; Células Madre Neoplásicas/metabolismo; Factor 3 de Transcripción de Unión a Octámeros/metabolismo; Péptidos; Neoplasias de la Próstata; Receptores de Esteroides/metabolismo; Receptores de Hormona Tiroidea/metabolismo; Taxoides/farmacología; Antígeno AC133; Línea Celular Tumoral; Docetaxel; Resistencia a Antineoplásicos/genética; Regulación Neoplásica de la Expresión Génica/efectos de los fármacos; Regulación Neoplásica de la Expresión Génica/genética; Técnicas de Silenciamiento del Gen; Humanos; Proteína Antagonista del Receptor de Interleucina 1/genética; Masculino; Células Madre Neoplásicas/patología; Factor 3 de Transcripción de Unión a Octámeros/genética; Neoplasias de la Próstata/tratamiento farmacológico; Neoplasias de la Próstata/genética; Neoplasias de la Próstata/metabolismo; Neoplasias de la Próstata/patología; Receptores de Esteroides/genética; Receptores de Hormona Tiroidea/genética

Palabras clave

Cancer Stem Cells; Chemoresistance; Drug Resistance; Nuclear Receptors; Oct4; Prostate Cancer; Testicular Orphan Nuclear Receptor 4

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Péptidos / Neoplasias de la Próstata / Células Madre Neoplásicas / Receptores de Hormona Tiroidea / Glicoproteínas / Receptores de Esteroides / Antígenos CD / Resistencia a Antineoplásicos / Taxoides / Factor 3 de Transcripción de Unión a Octámeros Límite: Humans / Male Idioma: En Revista: J Biol Chem Año: 2013 Tipo del documento: Article

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