Dengue virus envelope domain III immunization elicits predominantly cross-reactive, poorly neutralizing antibodies localized to the AB loop: implications for dengue vaccine design.

Li, Xiao-Quan; Qiu, Li-Wen; Chen, Yue; Wen, Kun; Cai, Jian-Piao; Chen, Jing; Pan, Yu-Xian; Li, Jie; Hu, Dong-Mei; Huang, Yan-Fen; Liu, Li-Dong; Ding, Xi-Xia; Guo, Yong-Hui; Che, Xiao-Yan

Li, Xiao-Quan; Qiu, Li-Wen; Chen, Yue; Wen, Kun; Cai, Jian-Piao; Chen, Jing; Pan, Yu-Xian; Li, Jie; Hu, Dong-Mei; Huang, Yan-Fen; Liu, Li-Dong; Ding, Xi-Xia; Guo, Yong-Hui; Che, Xiao-Yan.

Afiliación

Li XQ; Laboratory of Emerging Infectious Diseases, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, PR China.
Qiu LW; Division of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, PR China.
Chen Y; Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, PR China.
Wen K; Division of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, PR China.
Cai JP; Laboratory of Emerging Infectious Diseases, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, PR China.
Chen J; Division of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, PR China.
Pan YX; Laboratory of Emerging Infectious Diseases, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, PR China.
Li J; Division of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, PR China.
Hu DM; Laboratory of Emerging Infectious Diseases, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, PR China.
Huang YF; Division of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, PR China.
Liu LD; Laboratory of Emerging Infectious Diseases, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, PR China.
Ding XX; Division of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, PR China.
Guo YH; Laboratory of Emerging Infectious Diseases, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, PR China.
Che XY; Division of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, PR China.

J Gen Virol ; 94(Pt 10): 2191-2201, 2013 Oct.

Article en En | MEDLINE | ID: mdl-23851440

Asunto(s)

Anticuerpos Neutralizantes/inmunología; Anticuerpos Antivirales/inmunología; Vacunas contra el Dengue/inmunología; Virus del Dengue/inmunología; Proteínas del Envoltorio Viral/inmunología; Secuencia de Aminoácidos; Sustitución de Aminoácidos; Anticuerpos Monoclonales/inmunología; Reacciones Cruzadas; Vacunas contra el Dengue/química; Virus del Dengue/metabolismo; Mapeo Epitopo; Epítopos/química; Epítopos/inmunología; Modelos Moleculares; Pichia/metabolismo; Estructura Terciaria de Proteína; Proteínas del Envoltorio Viral/química; Proteínas del Envoltorio Viral/metabolismo

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas del Envoltorio Viral / Virus del Dengue / Vacunas contra el Dengue / Anticuerpos Neutralizantes / Anticuerpos Antivirales Idioma: En Revista: J Gen Virol Año: 2013 Tipo del documento: Article

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